• Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M 

      Hansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Stiberg, Kim Andre Ha; Sherstova, Tatyana; Wakita, Takaji; Richard, Gabriel Mary; Kandasamy, Richard Kumaran; Meurs, Eliane F.; Anthonsen, Marit Walbye (Journal article; Peer reviewed, 2017)
      Positive-stranded RNA viruses, such as hepatitis C virus (HCV), assemble their viral replication complexes by remodeling host intracellular membranes to a membranous web. The precise composition of these replication complexes ...
    • Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT 

      Dabo, Stephanie; Maillard, Patrick; Rodriguez, Milagros Collados; Hansen, Marianne Dore; Mazouz, Sabrina; Bigot, Donna-Joe; Tible, Marion; Janvier, Geneviève; Helynck, Oliver; Cassonnet, Patricia; Jacob, Yves; Bellalou, Jacques; Gatignol, Anne; Patel, Rekha C; Hugon, Jacques; Munier-Lehmann, Hélène; Meurs, Eliane F. (Journal article; Peer reviewed, 2017)
      PKR is a cellular kinase involved in the regulation of the integrative stress response (ISR) and pro-inflammatory pathways. Two N-terminal dsRNA Binding Domains (DRBD) are required for activation of PKR, by interaction ...