• Nanoscale Structure and Spectroscopic Probing of Aβ1-40 Fibril Bundle Formation 

      Psonka-Antonczyk, Katarzyna Maria; Hammarström, Per; Johansson, Leif B. G.; Lindgren, Mikael; Stokke, Bjørn Torger; Nilsson, K. Peter R.; Nyström, Sofie (Peer reviewed; Journal article, 2016)
      Amyloid plaques composed of fibrillar Amyloid-β (Aβ) are hallmarks of Alzheimer's disease. However, Aβ fibrils are morphologically heterogeneous. Conformation sensitive luminescent conjugated oligothiophenes (LCOs) are ...
    • Nanoscopic and Photonic Ultrastructural Characterization of Two Distinct Insulin Amyloid States 

      Psonka-Antonczyk, Katarzyna Maria; Duboisset, Julien; Stokke, Bjørn Torger; Zako, Tamotsu; Kobayashi, Takahiro; Maeda, Mizuo; Nyström, Sofie; Mason, Jeffrey; Hammarström, Per; Nilsson, K. Peter R.; Lindgren, Mikael (Journal article; Peer reviewed, 2012)
      Two different conformational isoforms or amyloid strains of insulin with different cytotoxic capacity have been described previously. Herein these filamentous and fibrillar amyloid states of insulin were investigated using ...
    • trans-Stilbenoids with Extended Fluorescence Lifetimes for the Characterization of Amyloid Fibrils 

      Zhang, Jun; Sandberg, Alexander; Wu, Xiongyu; Nyström, Sofie; Lindgren, Mikael; Konradsson, Peter; Hammarström, Per (Journal article; Peer reviewed, 2017)
      It was previously reported that two naphthyl-based trans-stilbene probes, (E)-4-(2-(naphthalen-1-yl)vinyl)benzene-1,2-diol (1) and (E)-4-(2-(naphthalen-2-yl)vinyl)benzene-1,2-diol (3), can bind to both native transthyretin ...