• Functional Toll-like receptors in primary first-trimester trophoblasts 

      Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Skei, Bente; Vikdal, Anne Jorunn; Ryan, Liv; Steinkjer, Bjørg; Myklebost, Merete; Langaas, Mette; Austgulen, Rigmor; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2014)
      Toll-like receptors (TLRs) are an important part of the body's danger response system and crucial for initiating inflammation in response to cellular stress, tissue damage, and infections. Proper placental development is ...
    • Metabolomic biomarkers in serum and urine in women with preeclampsia 

      Austdal, Marie; Skråstad, Ragnhild; Gundersen, Astrid; Austgulen, Rigmor; Iversen, Ann-Charlotte; Bathen, Tone Frost (Journal article, 2014)
      Objective To explore the potential of magnetic resonance (MR) metabolomics for study of preeclampsia, for improved phenotyping and elucidating potential clues to etiology and pathogenesis. Methods Urine and serum ...
    • The Norwegian preeclampsia family cohort study: a new resource for investigating genetic aspects and heritability of preeclampsia and related phenotypes 

      Roten, Linda Tømmerdal; Thomsen, Liv Cecilie Vestrheim; Gundersen, Astrid; Fenstad, Mona H.; Odland, Maria Lisa; Strand, Kristin Melheim; Solberg, Per; Tappert, Christian; Araya, Elisabeth; Bærheim, Gunhild Marie; Lyslo, Ingvill; Tollaksen, Kjersti; Bjørge, Line; Austgulen, Rigmor (Peer reviewed; Journal article, 2015)
      Background:Preeclampsia is a major pregnancy complication without curative treatment available. A NorwegianPreeclampsia Family Cohort was established to provide a new resource for genetic and molecular studies aiming ...
    • Toll-like receptor profiling of seven trophoblast cell lines warrants caution for translation to primary trophoblasts 

      Gierman, Lobke; Stødle, Guro; Tangerås, Line Haugstad; Austdal, Marie; Olsen, Guro Dalheim; Follestad, Turid; Skei, Bente; Rian, Kristin; Gundersen, Astrid; Austgulen, Rigmor; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2015)
      Introduction Excessive placental inflammation is associated with pregnancy complications. Toll-like receptors (TLRs) are sensors for danger signals from infections and damaged tissue and initiate inflammation. Trophoblasts ...