Browsing NTNU Open by Author "Gulati, Sasha"
Now showing items 1-20 of 76
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Accuracy and Complication Rates of External Ventricular Drain Placement With Twist Drill and Bolt System Versus Standard Trephine and Tunnelation: A Retrospective Population-Based Study
Mansoor, Nadia Mauland; Madsbu, Mattis Aleksander; Mansoor, Nina M.; Trønnes, Andreas; Fredriksli, Oddrun; Salvesen, Øyvind; Jakola, Asgeir S; Solheim, Ole; Gulati, Sasha (Peer reviewed; Journal article, 2020)Background: An external ventricular drain (EVD) is typically indicated in the presence of hydrocephalus and increased intracranial pressure (ICP). Procedural challenges have prompted the development of different methods ... -
Advancements in predicting outcomes in patients with glioma: a surgical perspective
Jakola, Asgeir S; Sagberg, Lisa Millgård; Gulati, Sasha; Solheim, Ole (Peer reviewed; Journal article, 2020)Introduction: Diffuse glioma is a challenging neurosurgical entity. Although surgery does not provide a cure, it may greatly influence survival, brain function, and quality of life. Surgical treatment is by nature highly ... -
Brain infarctions after glioma surgery: prevalence, radiological characteristics and risk factors
Strand, Per Sveino; Berntsen, Erik Magnus; Fyllingen, Even Hovig; Sagberg, Lisa Millgård; Reinertsen, Ingerid; Gulati, Sasha; Bouget, David; Solheim, Ole (Peer reviewed; Journal article, 2021)Background: Prevalence, radiological characteristics, and risk factors for peritumoral infarctions after glioma surgery are not much studied. In this study, we assessed shape, volume, and prevalence of peritumoral infarctions ... -
Brain infarctions following intracranial tumor surgery - incidence, risk factors, and clinical consequences
Strand, Per Sveino (Doctoral theses at NTNU;2023:164, Doctoral thesis, 2023)Norsk sammendrag Hjernesvulstkirurgi er ein balansegang mellom å fjerne mest mogleg av svulsten samstundes som ein ikkje skadar friskt, kringliggande hjernevev. Komplikasjonar i samband med kirurgi er ikkje til å kome ... -
Can a Successful Outcome After Surgery for Lumbar Disc Herniation Be Defined by the Oswestry Disability Index Raw Score?
Werner, David Andreas Thomas; Grotle, Margreth; Gulati, Sasha; Austevoll, Ivar Magne; Madsbu, Mattis Aleksander; Lønne, Greger; Solberg, Tore (Journal article; Peer reviewed, 2019)Study Design: Prospective multicenter cohort study. Objective: To investigate (1) the discriminative ability and cutoff estimates for success 12 months after surgery for lumbar disc herniation on the Oswestry Disability ... -
Clinical outcomes after surgery for cervical radiculopathy performed in public and private hospitals : a nationwide relative effectiveness study
Danielsen, Elisabet; Gulati, Sasha; Salvesen, Øyvind Olav; Ingebrigtsen, Tor; Nygaard, Øystein Petter; Solberg, Tore (Peer reviewed; Journal article, 2023)Aims The number of patients undergoing surgery for degenerative cervical radiculopathy has increased. In many countries, public hospitals have limited capacity. This has resulted in long waiting times for elective ... -
Comparative effectiveness of microdecompression and laminectomy for central lumbar spinal stenosis: Study protocol for an observational study
Nerland, Ulf Skule; Jakola, Asgeir Store; Solheim, Ole; Weber, Clemens; Rao, Vidar; Lønne, Greger; Solberg, Tore; Salvesen, Øyvind; Carlsen, Sven Magnus; Nygaard, Øystein Petter; Gulati, Sasha (Journal article; Peer reviewed, 2014)Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis. Lumbar spinal ... -
Cranial autonomic ganglia in headache disorders
Vidal, Joan Crespi (Doctoral theses at NTNU;2021:98, Doctoral thesis, 2021)Headache disorders are amongst the most prevalent causes of disability worldwide. Most of the effort to develop new therapeutics has focused on migraine. Patients suffering from less common headache disorders such as ... -
Depression and ability to work after vestibular schwannoma surgery: a nationwide registry-based matched cohort study on antidepressants, sedatives, and sick leave
Thurin, Erik; Förander, Petter; bartek, Jiri Jr.; Gulati, Sasha; Rydén, Isabelle; Smits, Anja; Hesselager, Göran; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2021)Background In patients with vestibular schwannomas (VS), tumor control is often achieved, and life expectancy is relatively good. The main risks of surgical treatment are hearing loss and facial nerve function. The occurrence ... -
Disulfiram repurposing combined with nutritional copper supplement as add-on to chemotherapy in recurrent glioblastoma (DIRECT): Study protocol for a randomized controlled trial
Jakola, Asgeir S.; Werlenius, Katja; Mudaisi, Munila; Hylin, Sofia; Kinhult, Sara; bartek, Jiri Jr.; Salvesen, Øyvind; Carlsen, Sven Magnus; Strandeus, Michael; Lindskog, Magnus; Lofgren, David; Rydenhaug, Bertil; Carstam, Louise; Gulati, Sasha; Solheim, Ole; Bartek, Jiri; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2018)Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to treat alcoholism since the 1950s. There is now independent preclinical data that supports DSF as an anticancer agent, and ... -
Effect of Arthroplasty vs Fusion for Patients With Cervical Radiculopathy: A Randomized Clinical Trial
Johansen, Tonje Okkenhaug; Sundseth, Jarle Østberg; Fredriksli, Oddrun; Andresen, Hege; Zwart, John-Anker; Kolstad, Frode; Pripp, Are Hugo; Gulati, Sasha; Nygaard, Øystein Petter (Peer reviewed; Journal article, 2021)Surgical treatment for cervical radiculopathy is increasing. Treatment with motion preserving anterior cervical disc arthroplasty was introduced to prevent symptomatic adjacent segment disease, and there is need to evaluate ... -
Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients with Recurrent Glioblastoma: A Randomized Clinical Trial
Werlenius, Katja; Kinhult, Sara; Solheim, Tora S; Magelssen, Henriette; Löfgren, David; Mudaisi, Munila; Hylin, Sofia; Bartek, Jiri; Strandéus, Michael; Lindskog, Magnus; Rashid, Havyan Bahroz; Carstam, Louise; Gulati, Sasha; Solheim, Ole Skeidsvoll; Salvesen, Øyvind Olav; Jakola, Asgeir Store (Peer reviewed; Journal article, 2023)Importance Disulfiram has demonstrated broad antitumoral effect in several preclinical studies. One of the proposed indications is for the treatment of glioblastoma. Objective To evaluate the efficacy and safety of ... -
Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial
Hara, Sozaburo; Andresen, Hege; Solheim, Ole; Carlsen, Sven Magnus; Sundstrøm, Terje; Lønne, Greger; Vangen-Lønne, Vetle; Taraldsen, Kristin; Tronvik, Erling Andreas; Øie, Lise Rystad; Gulati, Agnete Malm; Sagberg, Lisa Millgård; Jakola, Asgeir Store; Solberg, Tore; Nygaard, Øystein Petter; Salvesen, Øyvind; Gulati, Sasha (Peer reviewed; Journal article, 2022)Importance: The use of spinal cord stimulation for chronic pain after lumbar spine surgery is increasing, yet rigorous evidence of its efficacy is lacking. Objective: To investigate the efficacy of spinal cord burst ... -
Epidemiology and practice variations of shunt surgery for hydrocephalus: a nationwide registry-based study
Mansoor, Nadia; Gulati, Sasha; Fredriksli, Oddrun Anita; Salvesen, Øyvind Olav; Solheim, Ole Skeidsvoll (Peer reviewed; Journal article, 2023)OBJECTIVE Indications for surgical treatment of hydrocephalus (HC) can vary across centers. The authors sought to investigate the frequencies of surgically treated HC disorders and to study variations in the practice ... -
Epidemiology of diagnosed cluster headache in Norway
Vidal, Joan Crespi; Gulati, Sasha; Salvesen, Øyvind; Bratbak, Daniel Fossum; Dodick, David W; Matharu, Manjit Singh; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2022)Background: Cluster headache (CH) is one of the most painful conditions in humans and there is limited epidemiological data on this debilitating condition. Objectives: To describe the epidemiology of CH in Norway Methods: We ... -
ErbB receptors in human meningiomas
Arnli, Magnus Bossum (Doctoral theses at NTNU;2019:183, Doctoral thesis, 2019)Background: Meningiomas are the most common intracranial tumors in adults. They originate in the meninges, can grow to substantial size, and are in most cases benign. Recurrence; however, frequently occurs regardless of ... -
Evaluation of the proliferation markers Ki-67/MIB-1, mitosin, survivin, pHH3, and DNA topoisomerase II alpha in human anaplastic astrocytomas - an immunohistochemical study
Habberstad, Andreas Hanssønn; Gulati, Sasha; Torp, Sverre Helge (Journal article; Peer reviewed, 2011)Background Histological malignancy grading of astrocytomas can be challenging despite criteria given by the World Health Organisation (WHO). Grading is fundamental for optimal prognostication and treatment, and additional ... -
Expression and clinical value of EGFR in human meningiomas
Arnli, Magnus B.; Backer-Grøndahl, Thomas; Ytterhus, Borgny; Granli, Unn S.; Lydersen, Stian; Gulati, Sasha; Torp, Sverre Helge (Journal article; Peer reviewed, 2017)Background Meningiomas are common intracranial tumors in humans that frequently recur despite having a predominantly benign nature. Even though these tumors have been shown to commonly express EGFR/c-erbB1 (epidermal ... -
Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population-based study
Øie, Lise Rystad; Madsbu, Mattis Aleksander; Solheim, Ole; Jakola, Asgeir Store; Giannadakis, Charalampis; Vorhaug, Anders; Padayachy, Llewellyn; Jensberg, Heidi; Dodick, David W.; Salvesen, Øyvind; Gulati, Sasha (Journal article; Peer reviewed, 2018)Background Accurate and reliable clinical and radiological predictors of intracerebral hemorrhage (ICH) outcomes are needed to optimize treatment of ICH. The aim of this study was to investigate functional outcome and ... -
Impact of meningioma surgery on use of antiepileptic, antidepressant, and sedative drugs: A Swedish nationwide matched cohort study
Thurin, Erik; Rydén, Isabelle; Skoglund, Thomas; Smits, Anja; Gulati, Sasha; Hesselager, Göran; Bartek, Jiri Jr.; Henriksson, Roger; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2021)Background: Meningioma is the most common primary intracranial tumor and surgery is the main treatment modality. As death from lack of tumor control is rare, other outcome measures like anxiety, depression and post-operative ...