Blar i NTNU Open på forfatter "Gulati, Sasha"
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Can a Successful Outcome After Surgery for Lumbar Disc Herniation Be Defined by the Oswestry Disability Index Raw Score?
Werner, David Andreas Thomas; Grotle, Margreth; Gulati, Sasha; Austevoll, Ivar Magne; Madsbu, Mattis Aleksander; Lønne, Greger; Solberg, Tore (Journal article; Peer reviewed, 2019)Study Design: Prospective multicenter cohort study. Objective: To investigate (1) the discriminative ability and cutoff estimates for success 12 months after surgery for lumbar disc herniation on the Oswestry Disability ... -
Comparative effectiveness of microdecompression and laminectomy for central lumbar spinal stenosis: Study protocol for an observational study
Nerland, Ulf Skule; Jakola, Asgeir Store; Solheim, Ole; Weber, Clemens; Rao, Vidar; Lønne, Greger; Solberg, Tore; Salvesen, Øyvind; Carlsen, Sven Magnus; Nygaard, Øystein Petter; Gulati, Sasha (Journal article; Peer reviewed, 2014)Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis. Lumbar spinal ... -
Disulfiram repurposing combined with nutritional copper supplement as add-on to chemotherapy in recurrent glioblastoma (DIRECT): Study protocol for a randomized controlled trial
Jakola, Asgeir S.; Werlenius, Katja; Mudaisi, Munila; Hylin, Sofia; Kinhult, Sara; bartek, Jiri Jr.; Salvesen, Øyvind; Carlsen, Sven Magnus; Strandeus, Michael; Lindskog, Magnus; Lofgren, David; Rydenhaug, Bertil; Carstam, Louise; Gulati, Sasha; Solheim, Ole; Bartek, Jiri; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2018)Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to treat alcoholism since the 1950s. There is now independent preclinical data that supports DSF as an anticancer agent, and ... -
ErbB receptors in human meningiomas
Arnli, Magnus Bossum (Doctoral theses at NTNU;2019:183, Doctoral thesis, 2019)Background: Meningiomas are the most common intracranial tumors in adults. They originate in the meninges, can grow to substantial size, and are in most cases benign. Recurrence; however, frequently occurs regardless of ... -
Evaluation of the proliferation markers Ki-67/MIB-1, mitosin, survivin, pHH3, and DNA topoisomerase II alpha in human anaplastic astrocytomas - an immunohistochemical study
Habberstad, Andreas Hanssønn; Gulati, Sasha; Torp, Sverre Helge (Journal article; Peer reviewed, 2011)Background Histological malignancy grading of astrocytomas can be challenging despite criteria given by the World Health Organisation (WHO). Grading is fundamental for optimal prognostication and treatment, and additional ... -
Expression and clinical value of EGFR in human meningiomas
Arnli, Magnus B.; Backer-Grøndahl, Thomas; Ytterhus, Borgny; Granli, Unn S.; Lydersen, Stian; Gulati, Sasha; Torp, Sverre Helge (Journal article; Peer reviewed, 2017)Background Meningiomas are common intracranial tumors in humans that frequently recur despite having a predominantly benign nature. Even though these tumors have been shown to commonly express EGFR/c-erbB1 (epidermal ... -
Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population-based study
Øie, Lise Rystad; Madsbu, Mattis Aleksander; Solheim, Ole; Jakola, Asgeir Store; Giannadakis, Charalampis; Vorhaug, Anders; Padayachy, Llewellyn; Jensberg, Heidi; Dodick, David W.; Salvesen, Øyvind; Gulati, Sasha (Journal article; Peer reviewed, 2018)Background Accurate and reliable clinical and radiological predictors of intracerebral hemorrhage (ICH) outcomes are needed to optimize treatment of ICH. The aim of this study was to investigate functional outcome and ... -
Inter-and Intraobserver Agreement of Morphological Grading for Central Lumbar Spinal Stenosis on Magnetic Resonance Imaging
Weber, Clemens; Rao, Vidar; Gulati, Sasha; Kvistad, Kjell Arne; Nygaard, Øystein Petter; Lønne, Greger (Journal article; Peer reviewed, 2015)Study Design Validation study of a morphological grading system for central lumbar spinal stenosis. Objective To evaluate and validate the inter- and intraobserver agreement of a morphological grading system for central ... -
Metabolic profiles of brain metastases
Sjøbakk, Torill Eidhammer; Vettukattil, Riyas M; Gulati, Michel; Gulati, Sasha; Lundgren, Steinar; Gribbestad, Ingrid S; Torp, Sverre Helge; Bathen, Tone Frost (Journal article; Peer reviewed, 2013)Metastasis to the brain is a feared complication of systemic cancer, associated with significant morbidity and poor prognosis. A better understanding of the tumor metabolism might help us meet the challenges in controlling ... -
Open discectomy vs microdiscectomy for lumbar disc herniation - a protocol for a pragmatic comparative effectiveness study
Sørlie, Andreas; Gulati, Sasha; Giannadakis, Charalampis; Carlsen, Sven Magnus; Salvesen, Øyvind; Nygaard, Øystein Petter; Solberg, Tore (Journal article; Peer reviewed, 2016)Introduction: Since the introduction of lumbar microdiscectomy in the 1970’s, many studies have attempted to compare the effectiveness of this method with that of standard open discectomy with conflicting results. This ... -
Population-based observational studies on intracranial hemorrhage
Øie, Lise Rystad (Doctoral theses at NTNU;2020:308, Doctoral thesis, 2020)Populasjon- og registerbasert forskning på intrakranielle blødninger Formålet med denne doktorgradsavhandlingen var å studere ulike typer hjerneblødning i Norge. Det finnes allerede mange studier på hjerneblødning, men ... -
Post-traumatic epidural tension pneumocephalus: a case report
Rao, Vidar; Fredriksli, Oddrun; Gulati, Sasha (Journal article; Peer reviewed, 2015)Abstract Introduction: Pneumocephalus is usually a self-limiting condition commonly associated with neurosurgical interventions, head and facial trauma. In contrast, tension pneumocephalus is extremely rare, and considered ... -
Postoperative deterioration in health related quality of life as predictor for survival in patients with glioblastoma: a prospective study
Jakola, Asgeir S; Gulati, Sasha; Weber, Clemens; Unsgård, Geirmund; Solheim, Ole (Journal article; Peer reviewed, 2011)Background: Studies indicate that acquired deficits negatively affect patients' self-reported health related quality of life (HRQOL) and survival, but the impact of HRQOL deterioration after surgery on survival has not ... -
Quantitative texture analysis in the prediction of IDH status in low-grade gliomas
Jakola, Asgeir Store; Zang, YH; Skjulsvik, Anne Jarstein; Solheim, Ole; Bø, Hans Kristian; Berntsen, Erik Magnus; Reinertsen, Ingerid; Gulati, Sasha; Förander, Petter; Brismar, Torkel B. (Journal article; Peer reviewed, 2017)Objectives Molecular markers provide valuable information about treatment response and prognosis in patients with low-grade gliomas (LGG). In order to make this important information available prior to surgery the aim of ... -
Risk of intracranial hemorrhage (RICH) in users of oral antithrombotic drugs: Nationwide pharmacoepidemiological study
Gulati, Sasha; Solheim, Ole; Carlsen, Sven Magnus; Øie, Lise Rystad; Jensberg, Heidi; Gulati, Agnete Malm; Madsbu, Mattis Aleksander; Giannadakis, Charalampis; Jakola, Asgeir Store; Salvesen, Øyvind (Journal article; Peer reviewed, 2018)Background The risks of intracranial haemorrhage (ICH) associated with antithrombotic drugs outside clinical trials are gaining increased attention. The aim of this nationwide study was to investigate the risk of ICH ... -
Spatial distribution of malignant transformation in patients with low-grade glioma
Jakola, Asgeir S; Bouget, David Nicolas Jean-Marie; Reinertsen, Ingerid; Skjulsvik, Anne Jarstein; Sagberg, Lisa Millgård; Bø, Hans Kristian; Gulati, Sasha; Sjåvik, Kristin; Solheim, Ole (Journal article; Peer reviewed, 2020)Background Malignant transformation represents the natural evolution of diffuse low-grade gliomas (LGG). This is a catastrophic event, causing neurocognitive symptoms, intensified treatment and premature death. However, ... -
Surgery for Degenerative Lumbar Spinal Stenosis: Observational Studies Based on Data from the Norwegian Registry for Spine Surgery
Giannadakis, Charalampis (Doctoral thesis at NTNU;2016:258, Doctoral thesis, 2016)The topic of this doctoral thesis is surgery for lumbar spinal stenosis (LSS), a disease in the spinal column. This is a degenerative condition with reduced space in the spinal canal due to age-related changes of the ... -
Surgical management of lumbar spinal stenosis: Observational studies based on the Norwegian registry for spine surgery
Nerland, Ulf Skule (Doctoral thesis at NTNU;2016:50, Doctoral thesis, 2016)SUMMARY: This doctoral thesis deals with the surgical management of lumbar spinal stenosis (LSS), a disease in the spinal column. This is a degenerative condition with reduced space in the spinal canal due to age-related ... -
Surgical Resection of High-Grade Gliomas
Gulati, Sasha (Doktoravhandlinger ved NTNU, 1503-8181; 2012:105, Doctoral thesis, 2012)Reseksjon av høygradige gliomer Høygradige gliomer er den vanligste formen for primær hjernesvulst. Glioblastomer (Verdens Helseorganisasjon grad IV) og anaplastiske astrocytomer (Verdens Helseorganisasjon grad III) utgjør ... -
Surgically acquired deficits and diffusion weighted MRI changes after glioma resection - A matched case-control study with blinded neuroradiological assessment
Jakola, Asgeir S; Berntsen, Erik Magnus; Christensen, Pål; Gulati, Sasha; Unsgård, Geirmund; Kvistad, Kjell Arne; Solheim, Ole (Journal article; Peer reviewed, 2014)Background: Acquired deficits following glioma resection may not only occur due to accidental resection of normal brain tissue. The possible importance of ischemic injuries in causing neurological deficits after brain ...