Blar i NTNU Open på forfatter "Grill, Valdemar"
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Alginate Microencapsulation of Human Islets Does Not Increase Susceptibility to Acute Hypoxia
Hals, Ingrid Katrin; Rokstad, Anne Mari; Strand, Berit Løkensgard; Oberholzer, José; Grill, Valdemar (Journal article; Peer reviewed, 2013)Islet transplantation in diabetes is hampered by the need of life-long immunosuppression. Encapsulation provides partial immunoprotection but could possibly limit oxygen supply, a factor that may enhance hypoxia-induced ... -
Associations between the FTO rs9939609 genotypes and insulin sensitivity, glucose tolerance, energy metabolism, appetite hormones, and diet in patients with severe obesity
de Soysa, Ann Kristin Hjelle (Doctoral theses at NTNU;2022:398, Doctoral thesis, 2022) -
Impact of HLA DR3DQ2 and DR4DQ8 haplotypes on autoimmunity, diabetic phenotype, and comorbidity in individuals with LADA: An analysis of data from two clinical trials and the HUNT study
Lønnum, Birte Emilie Ellingsen (Master thesis, 2024)Bakgrunn og hensikt: De viktigste genene assosiert med risiko for autoimmun diabetes er haplotypene HLA-DR3DQ2 og HLA-DR4DQ8. Deres påvirkning på autoimmunitet, diabetisk fenotype og komorbiditet i Latent Autoimmun Diabetes ... -
LADA (latent autoimmune diabetes in adults) in Norway - occurence, risk factors, treatment and complications :
Carlsson, Sofia; Midthjell, Kristian; Grill, Valdemar (Journal article; Peer reviewed, 2013)LADA (latent autoimmune diabetes in adults) may be the most common form of autoimmune diabetes and thus encompasses a significant proportion of the diabetic population. Still, knowledge about this common form of diabetes ... -
Low C-peptide together with a high glutamic acid decarboxylase autoantibody level predicts progression to insulin dependence in latent autoimmune diabetes in adults: The HUNT study
Sørgjerd, Elin P.; Åsvold, Bjørn O.; Grill, Valdemar (Journal article; Peer reviewed, 2021)Aim: To search for risk factors that could predict progression in latent autoimmune diabetes in adults (LADA) and compare them with those for type 2 diabetes. Materials and Methods: This study included 175 participants ... -
On the susceptibility and adaptability of beta cells to stressful conditions: effects of nutrient scarcity, hyperoxia and internalization of amylin
Singh, Rinku (Doctoral theses at NTNU;2018:26, Doctoral thesis, 2018) -
Preconditioning with Associated Blocking of Ca2+ Inflow Alleviates Hypoxia-Induced Damage to Pancreatic β-Cells
Ma, ZH; Moruzzi, N; Catrina, SB; Hals, Ingrid Katrin; Oberholzer, J.; Grill, Valdemar; Björklund, A. (Journal article; Peer reviewed, 2013)Objective: Beta cells of pancreatic islets are susceptible to functional deficits and damage by hypoxia. Here we aimed to characterize such effects and to test for and pharmacological means to alleviate a negative impact ... -
Saving β-Cells from Demise:Effects of in vitro Conditions and Genetic Engineering of UCP-2
Hals, Ingrid Kathrin (Doktoravhandlinger ved NTNU, 1503-8181; 2014:106, Doctoral thesis, 2014)Motverking av skade på β-celler: effekt av endra in vitro-forhold og genetisk manipulering av UCP-2 Beta (β)-cellene, som produserer insulin, ligg samla i såkalla Langerhanske (L) øyer i bukspyttkjertelen. Ved diabetes er ... -
Testing for effects of nicotine on mitochondrial and other functional parameters in insulin-producing ß-cells
Dadadottir, Lovisa Hansen (Master thesis, 2020)Bakgrunn: β-celler inneholder nikotinergiske respetorer, men deres funksjon og potensiell betydning når det kommer til diabetes er imidlertidig ikke fullstendig belyst. Nikotin er det mest aktive stoffet i tobakk og røyking ... -
Testing the flexibility of mitochondrial functioning in insulin-producing β-cells under diabetes like conditions in vitro
Kylling, Mari Slemmen (Master thesis, 2019)Bakgrunn: Kronisk hyperglykemi er skadelig for de insulinproduserende β-cellene i pankreas. Mitokondrienes funksjon i disse cellene er helt essensiell for at β-cellene skal fungere optimalt. Mitokondriene påvirkes trolig ...