• A 4-year follow-up of patients with medication-overuse headache previously included in a randomized multicentre study 

      Hagen, Knut; Albretsen, Claus; Vilming, Steinar; Salvesen, Rolf; Grønning, Marit; Helde, Grethe; Gravdahl, Gøril Bruvik; Zwart, John-Anker; Stovner, Lars Jacob (Journal article; Peer reviewed, 2011)
    • A biofeedback app for migraine: Development and usability study 

      Ingvaldsen, Sigrid Hegna; Tronvik, Erling Andreas; Brenner, Eiliv; Winnberg, Ingunn; Olsen, Alexander; Gravdahl, Gøril Bruvik; Stubberud, Anker (Peer reviewed; Journal article, 2021)
      Background: Biofeedback is effective in treating migraines. It is believed to have a beneficial effect on autonomous nervous system activity and render individuals resilient to stressors that may trigger a migraine. However, ...
    • Biofeedback Treatment App for Pediatric Migraine: Development and Usability Study 

      Stubberud, Anker; Tronvik, Erling Andreas; Olsen, Alexander; Gravdahl, Gøril Bruvik; Linde, Mattias (Peer reviewed; Journal article, 2020)
      Objective The objective of this study was to develop and investigate the usability of a biofeedback treatment smartphone app for adolescent migraine sufferers. Background Biofeedback is effective in treating pediatric ...
    • Clinical and vascular responses to propranolol and candesartan in migraine patients: A randomized controlled clinical trial 

      Barzenje, Aros D; Gjesdal, Knut; Winsvold, Bendik K S; Småstuen, Milada Cvancarova; Stovner, Lars Jacob; Gravdahl, Gøril Bruvik; Nilsen, Kristian Bernhard (Journal article, 2020)
      Background: Both propranolol and candesartan are prophylactic drugs for migraine, but with unknown mechanisms of action. The objectives of the present study were to investigate these drugs’ effects on arterial wall dynamics ...
    • Continuous positive airway pressure in cluster headache: A randomized, placebo-controlled, triple-blind, crossover study 

      Gravdahl, Gøril Bruvik; Aakerøy, Lars; Stovner, Lars Jacob; Engstrøm, Morten; Müller, Kai Ivar; Bjørk, Marte-Helene; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2023)
      Abstract Background Oxygen inhalation aborts cluster headache attacks, and case reports show the effect of continuous positive airway pressure. The aim of this study was to investigate the prophylactic effect of continuous ...
    • FollowTheSutures: Piloting a new way to administer onabotulinumtoxinA for chronic migraine. 

      Stovner, Lars Jacob; Hagen, Knut; Tronvik, Erling Andreas; Gravdahl, Gøril Bruvik; Burstein, Rami; Dodick, David W. (Peer reviewed; Journal article, 2022)
      Background Anatomical and experimental data indicate that onabotulinimtoxin A could be more efficient and cost-effective for treating chronic migraine with injections targeting the cranial sutures, where collaterals from ...
    • Forecasting migraine with machine learning based on mobile phone diary and wearable data 

      Stubberud, Anker; Ingvaldsen, Sigrid Hegna; Brenner, Eiliv; Winnberg, Ingunn Grøntveit; Olsen, Alexander; Gravdahl, Gøril Bruvik; Matharu, Manjit Singh; Nachev, Parashkev; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2023)
      Introduction Triggers, premonitory symptoms and physiological changes occur in the preictal migraine phase and may be used in models for forecasting attacks. Machine learning is a promising option for such predictive ...
    • Habituation of laser-evoked potentials by migraine phase: a blinded longitudinal study. 

      Uglem, Martin; Omland, Petter Moe; Stjern, Marit; Gravdahl, Gøril Bruvik; Sand, Trond (Journal article; Peer reviewed, 2017)
      Background Migraineurs seem to have cyclic variations in cortical excitability in several neurophysiological modalities. Laser-evoked potentials (LEP) are of particular interest in migraine because LEP specifically targets ...
    • Headache following head injury: a population-based longitudinal cohort study (HUNT) 

      Nordhaug, Lena Hoem; Hagen, Knut; Vik, Anne; Stovner, Lars Jacob; Follestad, Turid; Pedersen, Torunn; Gravdahl, Gøril Bruvik; Linde, Mattias (Journal article; Peer reviewed, 2018)
      Background Headache is the most frequent symptom following head injury, but long-term follow-up of headache after head injury entails methodological challenges. In a population-based cohort study, we explored whether ...
    • Insufficient sleep may alter cortical excitability near the migraine attack: A blinded TMS crossover study 

      Mykland, Martin Syvertsen; Uglem, Martin; Stovner, Lars Jacob; Brenner, Eiliv; Snoen, Mari Storli; Gravdahl, Gøril Bruvik; Sand, Trond Halfdan; Omland, Petter Moe (Peer reviewed; Journal article, 2023)
      Background Migraine is a brain disorder with a multifaceted and unexplained association to sleep. Brain excitability likely changes periodically throughout the migraine cycle. In this study we examine the effect of ...
    • Non-invasive cortical modulation of experimental pain in migraine 

      Uglem, Martin; Omland, Petter Moe; Engstrøm, Morten; Gravdahl, Gøril Bruvik; Linde, Mattias; Hagen, Knut; Sand, Trond (Journal article; Peer reviewed, 2016)
      Objective: To test the hypothesis that secondary somatosensory cortex (S2) is involved in the migraine pathogenesis, by exploring the effect of navigated repetitive transcranial magnetic stimulation (rTMS) to S2 on ...
    • Pituitary adenoma and headache 

      Gravdahl, Gøril Bruvik (Master thesis, 2015)
      Background: Although headache and pituitary adenoma are two prevalent conditions that may coexist, it has also been postulated that pituitary adenomas may cause secondary headaches that resemble primary headaches. ...
    • Pituitary adenoma and non-acute headache: is there an association, and does treatment help? 

      Gravdahl, Gøril Bruvik; Tronvik, Erling Andreas; Fougner, Stine Lyngvi; Solheim, Ole (Journal article; Peer reviewed, 2016)
      Objective Headache is a controversial indication for treatment of pituitary adenoma. We studied the possible relationship between pituitary adenomas and headache as well as the symptomatic effects of treatment. Met ...
    • Self-administered biofeedback treatment app for pediatric migraine: A randomized pilot study 

      Stubberud, Anker; Linde, Mattias; Brenner, Eiliv; Heier, Martin; Olsen, Alexander; Aamodt, Anne Hege; Gravdahl, Gøril Bruvik; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2020)
      Objective To investigate the effect size, safety, and tolerability of a therapist‐independent biofeedback treatment app among adolescent with migraine. Materials and Methods This was a prospective, 3:1 ratio randomized, ...
    • Sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study 

      Engstrøm, Morten; Hagen, Knut; Bjørk, Marte Helene; Stovner, Lars Jacob; Gravdahl, Gøril Bruvik; Stjern, Marit; Sand, Trond (Journal article; Peer reviewed, 2013)
      Background Our aim was to compare subjective and objective sleep quality and arousal in migraine and to evaluate the relationship between sleep quality and pain thresholds (PT) in controls, interictal, preictal and postictal ...
    • Sleep-related and non-sleep-related migraine: interictal sleep quality, arousals and pain thresholds 

      Engstrøm, Morten; Hagen, Knut; Bjørk, Marte Helene; Gravdahl, Gøril Bruvik; Sand, Trond (Journal article; Peer reviewed, 2013)
      Background The mechanisms associating sleep and migraine are unknown. No previous polysomnographic (PSG) or pain-threshold (PT) study has compared patients with sleep-related migraine attacks (SM), non-sleep related ...
    • The crossover design for migraine preventives: an analyses of four randomized placebo-controlled trials 

      Astrid Bjørke, Jenssen; Stovner, Lars Jacob; Tronvik, Erling Andreas; Sand, Trond; Helde, Grethe; Gravdahl, Gøril Bruvik; Hagen, Knut (Journal article; Peer reviewed, 2019)
      Aims To evaluate the crossover design in migraine preventive treatment trials by assessing dropout rate, and potential period and carryover effect in four placebo-controlled randomized controlled trials (RCTs). Methods In ...
    • The epidemiology of headache disorders: a face-to-face interview of participants in HUNT4 

      Hagen, Knut; Åsberg, Anders Nikolai; Uhlig, Benjamin Langsæter; Tronvik, Erling Andreas; Brenner, Eiliv; Stjern, Marit; Helde, Grethe; Gravdahl, Gøril Bruvik; Sand, Trond (Journal article; Peer reviewed, 2018)
      Background The primary aim of this cross-sectional population-based study was to evaluate the 1-year prevalence of common headache disorders by a face-to-face interview. Methods The fourth wave of Nord-Trøndelag ...
    • The relationship between obstructive sleep apnea and insomnia: a population-based cross-sectional polysomnographic study. 

      Uhlig, Benjamin Langsæter; Hagen, Knut; Engstrøm, Morten; Stjern, Marit; Gravdahl, Gøril Bruvik; Sand, Trond (Journal article; Peer reviewed, 2018)
      Background The relationship between insomnia and objectively measured obstructive sleep apnea (OSA) severity has not previously been investigated in both genders in the general population. The main aim of this population-based ...
    • Validation of questionnaires for restless legs syndrome in the general population: the Trøndelag Health Study (HUNT) 

      Filosa, James; Omland, Petter Moe; Hagen, Knut; Langsrud, Knut; Brenner, Eiliv; Knutsen, Andreas; Drange, Ole Kristian; Gravdahl, Gøril Bruvik; Stjern, Marit; Engstrøm, Morten; Sand, Trond (Peer reviewed; Journal article, 2022)
      Questionnaires for restless legs syndrome have rarely been validated against face-to-face interviews in the general population. We aimed to validate the modified Norwegian, seven-item Cambridge-Hopkins restless legs syndrome ...