Browsing NTNU Open by Author "Gormley, Padhraig"

Now showing items 1-3 of 3

    • Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles 

      Hautakangas, Heidi; Winsvold, Bendik K S; Ruotsalainen, Sanni; Bjornsdottir, Gyda; Harder, Aster V. E.; Kogelman, Lisette J. A.; Thomas, Laurent; Noordam, Raymond; Benner, Christian; Gormley, Padhraig; Artto, Ville; Banasik, Karina; Bjornsdottir, Anna; Boomsma, Dorret I.; Brumpton, Ben Michael; Burgdorf, Kristoffer Sølvsten; Buring, Julie E.; Chalmer, Mona Ameri; de Boer, Irene; Dichgans, Martin; Erikstrup, Christian; Färkkilä, Markus; Gabrielsen, Maiken Elvestad; Ghanbari, Mohsen; Hagen, Knut; Häppölä, Paavo; Hottenga, Jouke-Jan; Hrafnsdottir, Maria G.; Hveem, Kristian; Johnsen, Marianne Bakke; Kähönen, Mika; Kristoffersen, Espen Saxhaug; Kurth, Tobias; Lehtimäki, Terho; Lighart, Lannie; Magnusson, Sigurdur H.; Malik, Rainer; Pedersen, Ole Birger; Pelzer, Nadine; Penninx, Brenda W. J. H.; Ran, Caroline; Ridker, Paul M.; Rosendaal, Frits Richard; Sigurdardottir, Gudrun R.; Skogholt, Anne Heidi; Sveinsson, Olafur A.; Thorgeirsson, Thorgeir E.; Ullum, Henrik; Zwart, John Anker Henrik (Peer reviewed; Journal article, 2022)
      Migraine affects over a billion individuals worldwide but its genetic underpinning remains largely unknown. Here, we performed a genome-wide association study of 102,084 migraine cases and 771,257 controls and identified ...

    • HMG-CoA reductase is a potential therapeutic target for migraine: a mendelian randomization study 

      Qu, Kang; Li, Ming-Xi; Yu, Peng; Palotie, Aarno; Pressman, Alice; Belin, Andrea C.; Bjornsdottir, Anna; van den Maagdenberg, Arn M. J. M.; Harder, Aster V. E.; Winsvold, Bendik Kristoffer Slagsvold; Müller-Myhsok, Bertram; Cormand, Bru; Ran, Caroline; Northover, Carrie; Kubisch, Christian; van Duijn, Cornelia; Nyholt, Dale R.; Chasman, Daniel I.; Posthuma, Danielle; Lessel, Davor; Boomsma, Dorret I.; Hämäläinen, Eija; Kristoffersen, Espen Saxhaug; Cuenca-Leon, Ester; Davey-Smith, George; Terwindt, Gisela M.; Sigurdardottir, Gudrun R.; Bjornsdottir, Gyda; Hautakangas, Heidi; Stefansson, Hreinn; de Boer, Irene; Kaprio, Jaakko; Olesen, Jes; Zwart, John Anker Henrik; Stefansson, Kari; Ligthart, Lannie; Launer, Lenore; Pedersen, Linda Margareth; Kogelman, Lisette J. A.; Griffiths, Lyn R.; Ikram, M. Arfan; Wessman, Maija; Kaunisto, Mari; Hrafnsdottir, Maria G.; Hiekkala, Marjo; Järvelin, Marjo-Riitta; Dichgans, Martin; Pirinen, Matti; Kallela, Mikko; Kurki, Mitja; Chalmer, Mona A.; Pedersen, Nancy; Sveinsson, Olafur A.; Raitakari, Olli; Gormley, Padhraig; Pozo-Rosich, Patricia; Palta, Priit; Malik, Rainer; Kajanne, Risto; Børte, Sigrid; Magnusson, Sigurdur H.; Lehtimäki, Terho; Hansen, Thomas F; Thorgeirsson, Thorgeir E.; Freilinger, Tobias; Kurth, Tobias; Esko, Tonu; Anttila, Verneri; Artto, Ville; Wu, Bai-Hua; Shi, Miao; Dong, Ming (Peer reviewed; Journal article, 2024)
      Statins are thought to have positive effects on migraine but existing data are inconclusive. We aimed to evaluate the causal effect of such drugs on migraines using Mendelian randomization. We used four types of genetic ...

    • Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants 

      Winsvold, Bendik K S; Bettella, Francesco; Witoelar, A; Anttila, Verneri; Gormley, Padhraig; Kurth, Tobias; Terwindt, Gisela M; Freilinger, Tobias; Frei, Oleksandr; Shadrin, Alexey A.; Wang, Yunpeng; Dale, Anders; Van Den Maagdenberg, Arn M.J.M.; Chasman, Daniel I; Nyholt, Dale R; Palotie, Aarno; Andreassen, Ole Andreas; Zwart, John-Anker (Journal article; Peer reviewed, 2017)
      Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little is known of its vascular basis. In epidemiological studies migraine is associated with an increased risk of cardiovascular ...