• Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses 

      Islam, Rakibul; Islam, Mohammad Mirazul; Nilsson, Per H.; Mohlin, Camilla; Hagen, Kjersti Thorvaldsen; Paschalis, Eleftherios I.; Woods, Russell L.; Bhowmick, Sabuj Chandra; Dohlman, Claes H.; Espevik, Terje; Chodosh, James; Gonzalez-Andrades, Miguel; Mollnes, Tom Eirik (Peer reviewed; Journal article, 2021)
      Inadequate supplies of donor corneas have evoked an escalating interest in corneal xenotransplantation. However, innate immune responses contribute significantly to the mechanism of xenograft rejection. We hypothesized ...
    • Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts 

      Islam, Mohammad Mirazul; Sharifi, Roholah; Mamodaly, Shamina; Islam, Rakibul; Nahra, Daniel; Abusamra, Dina B.; Hui, Pui Chuen; Adibnia, Yashar; Goulamaly, Mehdi; Paschalis, Eleftherios I.; Cruzat, Andrea; Kong, Jing; Nilsson, Per; Argüeso, Pablo; Mollnes, Tom Eirik; Chodosh, James; Dohlman, Claes H.; Gonzalez-Andrades, Miguel (Journal article; Peer reviewed, 2019)
      To address the shortcomings associated with corneal transplants, substantial efforts have been focused on developing new modalities such as xenotransplantion. Xenogeneic corneas are anatomically and biomechanically similar ...
    • Tuning gelatin-based hydrogel towards bioadhesive ocular tissue engineering applications 

      Sharifi, Sina; Islam, Mohammad Mirazul; Sharifi, Hannah; Islam, Rakibul; Koza, Darrell; Reyes-Ortega, Felisa; Alba-Molina, David; Nilsson, Per; Dohlman, Claes H.; Mollnes, Tom Eirik; Chodosh, James; Gonzalez-Andrades, Miguel (Peer reviewed; Journal article, 2021)
      Gelatin based adhesives have been used in the last decades in different biomedical applications due to the excellent biocompatibility, easy processability, transparency, non-toxicity, and reasonable mechanical properties ...