• A computational pipeline for quantification of mouse myocardial stiffness parameters 

      Nordbø, Øyvind; Lamata, P.; Land, Sander; Niederer, Steven A.; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Martens, Harald; Gjuvsland, Arne Bjørke; Tøndel, Kristin; Torp, Hans; Lohezic, M; Schneider, Jürgen; Remme, Espen W.; Smith, Nicolas P; Omholt, Stig W; Vik, Jon Olav (Journal article; Peer reviewed, 2014)
      The mouse is an important model for theoretical–experimental cardiac research, and biophysically based whole organ models of the mouse heart are now within reach. However, the passive material properties of mouse myocardium ...
    • Ancient Evolutionary Trade-Offs between Yeast Ploidy States 

      Zörgö, Enikö Beatrix; Chwialkowska, Karolina; Gjuvsland, Arne Bjørke; Garre, Elena; Sunnerhagen, Per; Liti, Gianni; Blomberg, Anders; Omholt, Stig W; Warringer, Jonas (Journal article; Peer reviewed, 2013)
      The number of chromosome sets contained within the nucleus of eukaryotic organisms is a fundamental yet evolutionarily poorly characterized genetic variable of life. Here, we mapped the impact of ploidy on the mitotic ...
    • Concerted Evolution of Life Stage Performances Signals Recent Selection on Yeast Nitrogen Use 

      Ibstedt, Sebastian; Stenberg, Simon; Bages, Sara; Gjuvsland, Arne Bjørke; Salinas, Francisco; Kourtchenko, Olga; Samy, Jeevan K.A.; Blomberg, Anders; Omholt, Stig William; Liti, Gianni; Beltran, Gemma; Warringer, Jonas (Journal article; Peer reviewed, 2015)
      Exposing natural selection driving phenotypic and genotypic adaptive differentiation is an extraordinary challenge. Given that an organism’s life stages are exposed to the same environmental variations, we reasoned that ...
    • Disentangling genetic and epigenetic determinants of ultrafast adaptation 

      Gjuvsland, Arne Bjørke; Zörgö, Enikö Beatrix; Antony Samy, Jeevan Karloss; Stenberg, Simon; Demirsoy, Ibrahim H; Roque, Francisco; Maciaszczyk-Dziubinska, Ewa; Migocka, Magdalena; Alonso-Perez, Elisa; Zackrisson, Martin; Wysocki, Robert; Tamas, Markus J; Jonassen, Inge; Omholt, Stig William; Warringer, Jonas (Journal article; Peer reviewed, 2016)
      A major rationale for the advocacy of epigenetically mediated adaptive responses is that they facilitate faster adaptation to environmental challenges. This motivated us to develop a theoretical–experimental framework for ...
    • Effect of regulatory architecture on broad versus narrow sense heritability 

      Wang, Yunpeng; Vik, Jon Olav; Omholt, Stig W; Gjuvsland, Arne Bjørke (Journal article; Peer reviewed, 2013)
      Additive genetic variance (VA) and total genetic variance (VG) are core concepts in biomedical, evolutionary and production-biology genetics. What determines the large variation in reported VA/VG ratios from line-cross ...
    • Life-stage associated remodeling of lipid metabolism regulation in Atlantic salmon 

      Gillard, Gareth Benjamin; Harvey, Thomas Nelson; Gjuvsland, Arne Bjørke; Jin, Yang; Thomassen, Magny Sissel S.; Lien, Sigbjørn; Leaver, Michael; Torgersen, Jacob Seilø; Hvidsten, Torgeir Rhoden; Vik, Jon Olav; Sandve, Simen Rød (Journal article; Peer reviewed, 2018)
      Atlantic salmon migrates from rivers to sea to feed, grow and develop gonads before returning to spawn in freshwater. The transition to marine habitats is associated with dramatic changes in the environment, including water ...
    • Monotonicity is a key feature of genotype-phenotype maps 

      Gjuvsland, Arne Bjørke; Wang, Yunpeng; Plahte, Erik; Omholt, Stig W (Journal article; Peer reviewed, 2013)
      It was recently shown that monotone gene action, i.e., order-preservation between allele content and corresponding genotypic values in the mapping from genotypes to phenotypes, is a prerequisite for achieving a predictable ...
    • Propagation of genetic variation in gene regulatory networks 

      Plahte, Erik; Gjuvsland, Arne Bjørke; Omholt, Stig W (Journal article; Peer reviewed, 2013)
      A future quantitative genetics theory should link genetic variation to phenotypic variation in a causally cohesive way based on how genes actually work and interact. We provide a theoretical framework for predicting and ...
    • The Atlantic salmon genome provides insights into rediploidization 

      Lien, Sigbjørn; Koop, Ben F; Sandve, Simen Rød; Miller, Jason R.; Kent, Matthew Peter; Nome, Torfinn; Hvidsten, Torgeir Rhoden; Leong, Jong; Minkley, David R.; Zimin, Aleksey; Grammes, Fabian; Grove, Harald; Gjuvsland, Arne Bjørke; Walenz, Brian; Hermansen, Russell A.; von Schalburg, Kristian R.; Rondeau, Eric; Genova, Alex Di; Antony Samy, Jeevan Karloss; Vik, Jon Olav; Vigeland, Magnus Dehli; Caler, Lis; Grimholt, Unni; Jentoft, Sissel; Våge, Dag Inge; de Jong, Pieter J.; Moen, Thomas; Baranski, Matthew; Palti, Yniv; Smith, Douglas W.; Yorke, James A.; Nederbragt, Alexander J.; Tooming-Klunderud, Ave; Jakobsen, Kjetill Sigurd; Jiang, Xuanting; Fan, Dingding; Hu, Yan; Liberles, David A.; Vidal, Rodrigo; Iturra, Patricia; Jones, Steven J.M.; Jonassen, Inge; Maass, Alejandro; Omholt, Stig William; Davidson, William S (Journal article; Peer reviewed, 2016)
      The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique opportunities to learn about the evolutionary fate ...
    • Transcriptional development of phospholipid and lipoprotein metabolism in different intestinal regions of Atlantic salmon (Salmo salar) fry 

      Jin, Yang; Olsen, Rolf Erik; Østensen, Mari-Ann; Gillard, Gareth Benjamin; Korsvoll, Sven Arild; Santi, Nina; Gjuvsland, Arne Bjørke; Vik, Jon Olav; Torgersen, Jacob Seilø; Sandve, Simen Rød; Olsen, Yngvar (Journal article; Peer reviewed, 2018)
      Background It has been suggested that the high phospholipid (PL) requirement in Atlantic salmon (Salmo salar) fry is due to insufficient intestinal de-novo synthesis causing low lipoprotein (LP) production and reduced ...