• Alcohol‐attributed disease burden in four Nordic countries between 2000 and 2017: Are the gender gaps narrowing? A comparison using the Global Burden of Disease, Injury and Risk Factor 2017 study 

      Agardh, Emilie, E.; Allebeck, Peter; Flodin, Pär; Wenneberg, Peter; Ramstedt, Mats; Knudsen, Ann Kristin; Øverland, Simon Nygaard; Kinge, Jonas Minet; Tollånes, Mette C.; Eikemo, Terje Andreas; Skogen, Jens Christoffer; Mäkelä, Pia; Gissler, Mika; Juel, Knud; Iburg, Kim Moesgaard; McGrath, John J.; Naghavi, Mohsen; Vollset, Stein Emil; Gakidou, Emmanuela; Danielsson, Anna-Karin (Peer reviewed; Journal article, 2020)
      Introduction and Aims The gender difference in alcohol use seems to have narrowed in the Nordic countries, but it is not clear to what extent this may have affected differences in levels of harm. We compared gender ...
    • Antenatal corticosteroid treatment and infectious diseases in children: a nationwide observational study 

      Räikkönen, Katri; Gissler, Mika; Kajantie, Eero Olavi; Tapiainen, Terhi (Peer reviewed; Journal article, 2023)
      Background Antenatal Corticosteroid Treatment (ACT) improves the outcome of preterm infants, but may influence immune system development and risk of immune-related diseases. We investigated whether ACT is associated ...
    • Associations between Maternal Antenatal Corticosteroid Treatment and Psychological Developmental and Neurosensory Disorders in Children 

      Räikkönen, Katri; Gissler, Mika; Tapiainen, Terhi; Kajantie, Eero Olavi (Peer reviewed; Journal article, 2022)
      Importance Corticosteroids administered to women at risk of imminent preterm birth is one of the most effective ways to improve the prognosis of infants born preterm. Scant data about long-term neurodevelopmental and ...
    • Associations of low sex hormone-binding globulin and androgen excess in early pregnancy with fasting and post-prandial hyperglycaemia, gestational diabetes, and its severity 

      Mustaniemi, Sanna; Morin-Papunen, Laure; Keikkala, Elina; Öhman, Hanna; Surcel, Heljä-Marja; Kaaja, Risto; Gissler, Mika; Eriksson, Johan G.; Laivuori, Hannele; Kajantie, Eero Olavi; Vääräsmäki, Marja (Peer reviewed; Journal article, 2022)
      Aims We studied whether androgen excess and low sex hormone-binding globulin (SHBG) measured in early pregnancy are independently associated with fasting and post-prandial hyperglycaemia, gestational diabetes (GDM), and ...
    • Burden of non-communicable disease studies in Europe: a systematic review of data sources and methodological choices 

      Charalampous, Periklis; Gorasso, Vanessa; Plass, Dietrich; Pires, Sara M.; von der Lippe, Elena; Mereke, Alibek; Idavain, Jane; Kissimova-Skarbek, Katarzyna; Nazaré Morgado, Joana; Ngwa, Che Henry; Noguer, Isabel; Padrón, Alicia; José Santi-Cano, María; Sarmiento, Rodrigo; Devleesschauwer, Brecht; Haagsma, Juanita; Balázs, Ádám; Alkerwi, Ala'a; Bikbov, Boris; Bølling, Anette Kocbach; Breitner, Susanne; Cuschieri, Sarah; Dahm, Christina Catherine; Eikemo, Terje Andreas; Fischer, Florian; Freitas, Alberto; García-González, Juan Manuel; Gazzelloni, Federica; Gissler, Mika; Hengl, Brigita; D Hynds, Paul; Isola, Gaetano; Sletting Jakobsen, Lea; Kabir, Zubair; Knudsen, Ann Kristin Skrindo; Meric Konar, Naime; Ladeira, Carina; Liew, Aaron; Majer, Marjeta; Aggelos Mechili, Enkeleint; Mevsim, Vildan; Santric Milicevic, Milena; Mitchell, Louise; Monasta, Lorenzo; Mondello, Stefania; Nena, Evangelia; Ng, Edmond S. W.; Niranjan, Vikram; O'Caoimh, Rónán; O'Donovan, Mark R; Ortiz, Alberto; Pallari, Elena; Petrou, Panagiotis; Reina Ortiz, Miguel; Riva, Silvia; Samouda, Hanen; Vasco Santos, João; Santoso, Cornelia; Schmitt, Tugce; Skempes, Dimitrios; Sousa, Ana Catarina; Stevanović, Aleksandar; Sulo, Gerhard; Terzic, Natasa; Terzic-Supic, Zorica; Todorovic, Jovana; Tozija, Fimka; Unim, Brigid; Van Wilder, Lisa; Varga, Orsolya; Saverio Violante, Francesco; Wyper, Grant M. A. (Peer reviewed; Journal article, 2022)
      Background Assessment of disability-adjusted life years (DALYs) resulting from non-communicable diseases (NCDs) requires specific calculation methods and input data. The aims of this study were to (i) identify existing ...
    • Cancer in children born after frozen-thawed embryo transfer: A cohort study 

      Sargisian, Nona; Lannering, Birgitta; Petzold, Max; Opdahl, Signe; Gissler, Mika; Pinborg, Anja; Henningsen, Anna-Karina Aaris; Tiitinen, Aila; Romundstad, Liv Bente Bergem; Spangmose, Anne Lærke; Bergh, Christina; Wennerholm, Ulla-Britt (Journal article; Peer reviewed, 2022)
    • Cardiovascular disease, obesity, and type 2 diabetes in children born after assisted reproductive technology: A population-based cohort study 

      Norrman, Emma; Petzold, Max; Gissler, Mika; Spangmose, Anne Lærke; Opdahl, Signe; Henningsen, Anna-Karina; Pinborg, Anja; Tiitinen, Aila; Rosengren, Annika; Romundstad, Liv Bente; Wennerholm, Ulla-Britt; Bergh, Christina (Peer reviewed; Journal article, 2021)
      Background Some earlier studies have found indications of significant changes in cardiometabolic risk factors in children born after assisted reproductive technology (ART). Most of these studies are based on small cohorts ...
    • The challenges of selective fertility and carryover effects in within-sibship analyses: the effect of assisted reproductive technology on perinatal mortality as an example 

      Westvik-Johari, Kjersti; Håberg, Siri Eldevik; Lawlor, Deborah A.; Romundstad, Liv Bente Bergem; Bergh, Christina; Wennerholm, Ulla-Britt; Gissler, Mika; Henningsen, Anna-Karina A.; Tiitinen, Aila; Pinborg, Anja; Opdahl, Signe (Peer reviewed; Journal article, 2023)
      Background Within-sibship analyses show lower perinatal mortality after assisted reproductive technology (ART) compared with natural conception (NC), a finding that appears biologically unlikely. We investigated whether ...
    • Characteristics of preeclampsia in donor cell gestations 

      Ervaala, Attina; Laivuori, Hannele; Gissler, Mika; Kere, Juha; Kivinen, Katja; Pouta, Anneli; Kajantie, Eero Olavi; Heinonen, Seppo; Wedenoja, Satu (Peer reviewed; Journal article, 2022)
      Pregnancies conceived through donor oocytes or sperm show increased risk for preeclampsia. We studied this issue in a preeclampsia case-control cohort (n = 2778), and found overrepresentation of donor cell gestations among ...
    • Data resource profile: the Committee of Nordic Assisted Reproductive Technology and Safety (CoNARTaS) cohort 

      Opdahl, Signe; Henningsen, Anna-Karina Aaris; Bergh, Christina; Gissler, Mika; Romundstad, Liv Bente Bergem; Petzold, Max; Tiitinen, Aila; Wennerholm, Ulla-Britt; Pinborg, Anja (Journal article; Peer reviewed, 2019)
    • Disease Burden Attributed to Drug use in the Nordic Countries: a Systematic Analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 

      Agardh, Emilie, E.; Allebeck, Peter; Knudsen, Ann Kristin Skrindo; Aronsson, Emma Amanda; Flodin, Pär; Eikemo, Terje Andreas; Bangah, Paul R.; Skogen, Jens Christoffer; Gissler, Mika; Rönkä, Sanna; McGrath, John J.; Sigurvinsdottir, Rannveig; Dadras, Omid; Deuba, Keshab; Hedna, Khedidja; Mentis, Alexios‑Fotios A.; Sagoe, Dominic; Shiri, Rahman; Weye, Nanna Ørslev; Hay, Simon I.; Murray, Christopher J. L.; Naghavi, Mohsen; Pasovic, Maja; Vos, Theo; Wennberg, Peter; Danielsson, Anna‑Karin (Peer reviewed; Journal article, 2023)
      The Nordic countries share similarities in many social and welfare domains, but drug policies have varied over time and between countries. We wanted to compare differences in mortality and disease burden attributed to drug ...
    • Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia 

      Wedenoja, Satu; Yoshihara, Masahito; Teder, Hindrek; Sariola, Hannu; Gissler, Mika; Katayama, Shintaro; Wedenoja, Juho; Häkkinen, Inka M.; Ezer, Sini; Linder, Nina; Lundin, Johan; Skoog, Tiina; Sahlin, Ellika; Iwarsson, Erik; Pettersson, Karin; Kajantie, Eero Olavi; Mokkonen, Mikael; Heinonen, Seppo; Laivuori, Hannele; Krjutškov, Kaarel; Kere, Juha (Peer reviewed; Journal article, 2020)
      Background Fetal immune tolerance is crucial for pregnancy success. We studied the link between preeclampsia, a severe pregnancy disorder with uncertain pathogenesis, and fetal human leukocyte antigen G (HLA-G) and other ...
    • Gestational diabetes is associated with the risk of offspring's congenital anomalies: a register-based cohort study 

      Kinnunen, Jenni; Nikkinen, Hilkka; Keikkala, Elina; Mustaniemi, Sanna; Gissler, Mika; Laivuori, Hannele; Eriksson, Johan G.; Kaaja, Risto; Pouta, Anneli; Kajantie, Eero Olavi; Vääräsmäki, Marja (Peer reviewed; Journal article, 2023)
      Background Gestational diabetes mellitus (GDM) is a common pregnancy-related disorder and a well-known risk factor for adverse pregnancy outcomes. There are conflicting findings on the association of GDM with the risk of ...
    • Increased Oral Care Needs and Third Molar Symptoms in Women with Gestational Diabetes Mellitus: A Finnish Gestational Diabetes Case-Control Study 

      Pukkila, Jenni; Mustaniemi, Sanna; Lingaiah, Shilpa; Lappalainen, Olli-Pekka; Kajantie, Eero Olavi; Pouta, Anneli; Kaaja, Risto; Eriksson, Johan G.; Laivuori, Hannele; Gissler, Mika; Vääräsmäki, Marja; Keikkala, Elina (Peer reviewed; Journal article, 2022)
      (1) Hyperglycemia and oral pathology accelerate each other in diabetes. We evaluated whether gestational diabetes mellitus (GDM) is associated with self-reported increased oral health care needs and oral symptoms, including ...
    • Independent and concomitant associations of gestational diabetes and maternal obesity to perinatal outcome: A register-based study 

      Ijas, Hilkka; Koivunen, Sanna; Raudaskoski, Tytti; Kajantie, Eero Olavi; Gissler, Mika; Vaarasmaki, Marja (Peer reviewed; Journal article, 2019)
      Aims Gestational diabetes (GDM) is often accompanied by maternal overweight. Our aim was to evaluate the separate and concomitant effects of GDM and maternal overweight/obesity on perinatal outcomes. Methods We used ...
    • Life expectancy and disease burden in the Nordic countries: results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 

      Kisa, Adnan; Knudsen, Ann Kristin; Allebeck, Peter; Tollånes, Mette Christophersen; Skogen, Jens Christoffer; Iburg, Kim Moesgaard; McGrath, John J; Juel, Knud; Agardh, Emilie Elisabet; Arnlöv, Johan; Bjørge, Tone; Carrero, Juan J.; Cederroth, Christopher R; Eggen, Anne Elise; El-Khatib, Ziad; Lycke Ellingsen, Christian; Fereshtehnejad, Seyed-Mohammad; Gissler, Mika; Hadkhale, Kishor; Havmoeller, Rasmus; Johansson, Lars; Juliusson, Petur Benedikt; Kiadaliri, Aliasghar A.; Kisa, Sezer; Lallukka, Tea; Mekonnen, Teferi; Meretoja, Tuomo J.; Meretoja, Atte; Naghavi, Mohsen; Neupane, Subas; Nguyen, Truc Trung; Petzold, Max; Plana-Ripoll, Oleguer; Shiri, Rahman; Sigurvinsdottir, Rannveig; Skirbekk, Vegard; Skou, Søren T; Sigfusdottir, Inga Dora; Steiner, Timothy J.; Sulo, Gerhard; Truelsen, Thomas Clement; Vasankari, Tommi Juhani; Weiderpass, Elisabete; Vollset, Stein Emil; Vos, Theo; Øverland, Simon (Journal article; Peer reviewed, 2019)
      Background The Nordic countries have commonalities in gender equality, economy, welfare, and health care, but differ in culture and lifestyle, which might create country-wise health differences. This study compared life ...
    • The neurodevelopmental morbidity of children born after assisted reproductive technology: a Nordic register study from the Committee of Nordic Assisted Reproductive Technology and Safety group 

      Rönö, Kristiina; Rissanen, Essi; Bergh, Christina; Wennerholm, Ulla-Britt; Opdahl, Signe; Romundstad, Liv Bente Bergem; Henningsen, Anna-Karina Aaris; Spangmose, Anne Lærke; Pinborg, Anja; Gissler, Mika; Tiitinen, Aila (Peer reviewed; Journal article, 2022)
      Objective To assess the risk of neurodevelopmental disorders in singletons born after the use of assisted reproductive technology (ART) compared with singletons born without the use of ART. Design Nordic register-based ...
    • Normal Gestational Weight Gain Protects From Large-for-Gestational-Age Birth Among Women With Obesity and Gestational Diabetes 

      Mustaniemi, Sanna; Nikkinen, Hilkka; Bloigu, Aini; Pouta, Anneli; Kaaja, Risto; Eriksson, Johan G.; Laivuori, Hannele; Gissler, Mika; Kajantie, Eero Olavi; Vääräsmäki, Marja (Peer reviewed; Journal article, 2021)
      Background: Pre-pregnancy obesity, excess gestational weight gain (GWG), and gestational diabetes (GDM) increase fetal growth. Our aim was to assess whether normal GWG is associated with lower risk for a large-for-gestational-age ...
    • Pregnancy outcomes according to the definition of gestational diabetes 

      Koivunen, Sanna; Viljakainen, Matti; Männistö, Tuija; Gissler, Mika; Pouta, Anneli; Kaaja, Risto; Eriksson, Johan G.; Laivuori, Hannele; Kajantie, Eero Olavi; Vääräsmäki, Marja (Peer reviewed; Journal article, 2020)
      Objective To assess the frequency and perinatal outcomes of gestational diabetes mellitus (GDM) defined by the criteria according to the International Association of Diabetes in Pregnancy Study Group (IADPSG) and the ...
    • Preterm birth and the risk of chronic disease multimorbidity in adolescence and early adulthood: A population-based cohort study 

      Heikkilä, Katriina; Pulakka, Anna; Metsälä, Johanna; Alenius, Suvi; Hovi, Petteri; Gissler, Mika; Sandin, Sven; Kajantie, Eero Olavi (Peer reviewed; Journal article, 2021)
      Background People who were born prematurely have high risks of many individual diseases and conditions in the early part of the life course. However, our knowledge of the burden of multiple diseases (multimorbidity) ...