Blar i NTNU Open på forfatter "Giampà, Marco"
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Bestemmelse av fosfolipidnivåer i EGF-behandlede brystkreftceller dyrket in vitro med hjelp av MALDI-MSI
With Andreassen, Veronica (Master thesis, 2022)Brystkreft er i dag den vanligste kreftrelaterte dødsårsaken blant kvinner i verden. Til tross for gode prognoser for de fleste molekylære undergruppene av brystkreft, er det også noen grupper som har svært dårlig prognose. ... -
Insight to Functional Conformation and Noncovalent Interactions of Protein-Protein Assembly Using MALDI Mass Spectrometry
Giampà, Marco; Sgobba, Elvira (Peer reviewed; Journal article, 2020)Noncovalent interactions are the keys to the structural organization of biomolecule e.g., proteins, glycans, lipids in the process of molecular recognition processes e.g., enzyme-substrate, antigen-antibody. Protein ... -
Polymerization as a Strategy to Improve Small Organic Matrices for Low-Molecular-Weight Compound Analytics with MALDI MS and MALDI MS Imaging
Horatz, Kilian; Giampà, Marco; Qiao, Zhi; Moestue, Siver A.; Lissel, Franziska (Peer reviewed; Journal article, 2021)Matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) and the corresponding visualizing technique MALDI MS imaging (MSI) are potent and widely used analytical methods in medical and pathological research. ... -
Relative Quantification Studies of Cabazitaxel from Poly(alkyl Cyanoacrylate) Nanoparticles Embedded in Alginate Beads by MALDI-Mass Spectrometry Imaging
Rolfsnes, Andreas Sortland (Master thesis, 2021)Nanopartikler (NP) gir store muligheter i forhold til konvensjonell kjemoterapi som har betydelige bivirkninger på grunn den farmasøytiske formuleringen. Karakterisering av nanomedisin er av stor betydning for å sikre ... -
Reproducible lipid alterations in patient-derived breast cancer xenograft FFPE tissue identified with MALDI MSI for pre-clinical and clinical application
Denti, Vanna; Andersen, Maria Karoline; Smith, Andrew; Bofin, Anna M.; Nordborg, Anna; Magni, Fulvio; Moestue, Siver Andreas; Giampà, Marco (Peer reviewed; Journal article, 2021)The association between lipid metabolism and long-term outcomes is relevant for tumor diagnosis and therapy. Archival material such as formalin-fixed and paraffin embedded (FFPE) tissues is a highly valuable resource for ... -
Unravel the Local Complexity of Biological Environments by MALDI Mass Spectrometry Imaging
Sgobba, Elvira; Daguerre, Yohann; Giampà, Marco (Peer reviewed; Journal article, 2021)Classic metabolomic methods have proven to be very useful to study functional biology and variation in the chemical composition of different tissues. However, they do not provide any information in terms of spatial ...