• Mechanistic Comparison between Gastric Bypass vs. Duodenal Switch with Sleeve Gastrectomy in Rat Models 

      Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård; Chen, Duan (Journal article; Peer reviewed, 2013)
      Background: Both gastric bypass (GB) and duodenal switch with sleeve gastrectomy (DS) have been widely used as bariatric surgeries, and DS appears to be superior to GB. The aim of this study was to better understand the ...
    • Relevance of TNBS-Colitis in Rats: A Methodological Study with Endoscopic, Historical and Transcripttomic Characterization and Correlation to IBD 

      Brenna, Øystein; Furnes, Marianne Waldum; Drozdov, Ignat; Granlund, Atle Van Beelen; Flatberg, Arnar; Sandvik, Arne Kristian; Zwiggelaar, Rosalie; Mårvik, Ronald; Nordrum, Ivar Skjåk; Kidd, Mark; Gustafsson, Björn (Journal article; Peer reviewed, 2013)
      Background: Rectal instillation of trinitrobenzene sulphonic acid (TNBS) in ethanol is an established model for inflammatory bowel disease (IBD). We aimed to 1) set up a TNBS-colitis protocol resulting in an endoscopic ...
    • The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease 

      Brenna, Øystein; Bruland, Torunn; Furnes, Marianne Waldum; Granlund, Atle Van Beelen; Drozdov, Ignat; Emgård, Johanna; Brønstad, Gunnar; Kidd, Mark; Sandvik, Arne Kristian; Gustafsson, Björn (Journal article; Peer reviewed, 2015)
      Objective. Activation of membrane receptor guanylate cyclase-C (GC-C) is implicated in gastrointestinal fluid and electrolyte balance, preservation of intestinal barrier integrity, anti-trophic effects and inhibition of ...