• A miniaturized ball-lensed fiber optic NIR transmission spectroscopy-based glucose sensor 

      Fuglerud, Silje Skeide; Milenko, Karolina Barbara; Larsen Jernelv, Ine; Ellingsen, Reinold; Aksnes, Astrid; Hjelme, Dag Roar (Chapter, 2018)
      A novel ball-lensed fiber transmission sensor is presented aimed at in vivo continuous glucose monitoring of diabetics. Preliminary results yield 20 mM RMSE, limited by mechanical instability. The design enables flexibility ...
    • A Review of Optical Methods for Continuous Glucose Monitoring 

      Jernelv, Ine Larsen; Milenko, Karolina Barbara; Fuglerud, Silje Skeide; Hjelme, Dag Roar; Ellingsen, Reinold; Aksnes, Astrid (Journal article; Peer reviewed, 2018)
      Frequent glucose monitoring is a fundamental part of diabetes management, and good glucose control is important for long-term health outcomes. New types of electrochemical sensors that allow for continuous glucose monitoring ...
    • Evanescent light field trapping and transport of micro- and nanocrystals of biological macromolecules on a waveguide for serial crystallography. 

      Fuglerud, Silje Skeide (Master thesis, 2016)
      A microfluidic evanescent field optical tweezer system was tested and developed for sample delivery of micro- and nanocrystals in serial crystallography. The fluid line was enforced, and the setup changed from vacuum ...
    • Feasibility of supercontinuum sources for use in glucose sensing by absorption spectroscopy 

      Fuglerud, Silje Skeide; Milenko, Karolina Barbara; Ellingsen, Reinold; Aksnes, Astrid; Hjelme, Dag Roar (Journal article; Peer reviewed, 2019)
      Diabetes mellitus 1 requires tight control of the blood glucose levels to avoid harmful effects of either too high (hyperglycemia) or too low (hypoglycemia) blood sugar. Due to the availability of low-cost components, ...
    • Glucose sensing by absorption spectroscopy using lensed optical fibers 

      Fuglerud, Silje Skeide; Milenko, Karolina Barbara; Ellingsen, Reinold; Aksnes, Astrid; Hjelme, Dag Roar (Journal article; Peer reviewed, 2019)
      The bulkiness of common transmission spectroscopy probes prevents applicability at remote locations such as within the body. We present the fabrication and characterization of lensed fibers for transmission spectroscopy ...
    • Investigation of the effect of clinically relevant interferents on glucose monitoring using near‐infrared spectroscopy 

      Fuglerud, Silje Skeide; Ellingsen, Reinold; Aksnes, Astrid; Hjelme, Dag Roar (Peer reviewed; Journal article, 2021)
      Near infrared spectroscopy (NIR) is a promising technique for continuous blood glucose monitoring for diabetic patients. Four interferents, at physiological concentrations, were introduced to study how the glucose predictions ...
    • Micro-lensed optical fibers for a surface-enhanced Raman scattering sensing probe 

      Milenko, Karolina Barbara; Fuglerud, Silje Skeide; Kjeldby, Snorre B; Ellingsen, Reinold; Aksnes, Astrid; Hjelme, Dag Roar (Journal article; Peer reviewed, 2018)
      We present the fabrication and characterization of a novel sensing configuration based on surface-enhanced Raman scattering (SERS) and two micro-lensed optical fibers. The first micro-lensed fiber is used to excite surface ...
    • Mix-and-diffuse serial synchrotron crystallography 

      Beyerlein, Kenneth R.; Dierksmeyer, Dennis; Mariani, Valerio; Kuhn, Manuela; Sarrou, Iosifina; Ottaviano, Angelica; Awel, Salah; Knoska, Juraj; Fuglerud, Silje Skeide; Jönsson, Olof; Stern, Stephan; Wiedorn, Max O.; Yefanov, Oleksandr; Adriano, Luigi; Bean, Richard; Burkhardt, Anja; Fischer, Pontus; Heymann, Michael; Horke, Daniel A.; Jungnickel, Katharina E.J.; Kovaleva, Elena; Lorbeer, Olga; Metz, Markus; Meyer, Jan; Morgan, Andrew; Pande, Kanupriya; Panneerselvam, Saravanan; Seuring, Carolin; Tolstikova, Aleksandra; Lieske, Julia; Aplin, Steve; Roessle, Manfred; White, Thomas A.; Chapman, Henry N.; Meents, Alke; Oberthuer, Dominik (Journal article; Peer reviewed, 2017)
      Unravelling the interaction of biological macromolecules with ligands and substrates at high spatial and temporal resolution remains a major challenge in structural biology. The development of serial crystallography methods ...
    • Optimization of SERS Sensing With Micro-Lensed Optical Fibers and Au Nano-Film 

      Milenko, Karolina Barbara; Fuglerud, Silje Skeide; Aksnes, Astrid; Ellingsen, Reinold; Hjelme, Dag Roar (Peer reviewed; Journal article, 2020)
      We present the fabrication and characterization of optical fiber reflection probes based on surface-enhanced Raman scattering (SERS) and micro-lensed multimode fibers. For the SERS substrate, a nano-sphere lithography ...
    • Surface-Enhanced Absorption Spectroscopy for Optical Fiber Sensing 

      Fuglerud, Silje Skeide; Milenko, Karolina Barbara; Aksnes, Astrid; Hjelme, Dag Roar (Peer reviewed; Journal article, 2020)
      Visible and near-infrared spectroscopy are widely used for sensing applications but suffer from poor signal-to-noise ratios for the detection of compounds with low concentrations. Enhancement by surface plasmon resonance ...
    • Towards Fiber-Optic Raman Spectroscopy for Glucose Sensing 

      Milenko, Karolina Barbara; Larsen Jernelv, Ine; Fuglerud, Silje Skeide; Aksnes, Astrid; Ellingsen, Reinold; Hjelme, Dag Roar (Chapter, 2018)
      We demonstrate a multimode optical fiber sensor for spectroscopic Raman measurements of glucose concentration for the application in intraperitoneal glucose detection in diabetic patients. A regression model with a RMSEC ...
    • Visualisation of Limb Movements by Accelerometers in Sedated Patients 

      Harbo, Erlend; Fuglerud, Silje Skeide; Skjaervold, Nils Kristian (Peer reviewed; Journal article, 2020)
      The prognostication of neurological outcome in sedated ICU patients is challenging. Multiple clinical scoring schemes and examinations are used, where different motoric responses are important input variables. Accelerometery ...