Browsing NTNU Open by Author "Freilinger, Tobias"

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    • HMG-CoA reductase is a potential therapeutic target for migraine: a mendelian randomization study 

      Qu, Kang; Li, Ming-Xi; Yu, Peng; Palotie, Aarno; Pressman, Alice; Belin, Andrea C.; Bjornsdottir, Anna; van den Maagdenberg, Arn M. J. M.; Harder, Aster V. E.; Winsvold, Bendik Kristoffer Slagsvold; Müller-Myhsok, Bertram; Cormand, Bru; Ran, Caroline; Northover, Carrie; Kubisch, Christian; van Duijn, Cornelia; Nyholt, Dale R.; Chasman, Daniel I.; Posthuma, Danielle; Lessel, Davor; Boomsma, Dorret I.; Hämäläinen, Eija; Kristoffersen, Espen Saxhaug; Cuenca-Leon, Ester; Davey-Smith, George; Terwindt, Gisela M.; Sigurdardottir, Gudrun R.; Bjornsdottir, Gyda; Hautakangas, Heidi; Stefansson, Hreinn; de Boer, Irene; Kaprio, Jaakko; Olesen, Jes; Zwart, John Anker Henrik; Stefansson, Kari; Ligthart, Lannie; Launer, Lenore; Pedersen, Linda Margareth; Kogelman, Lisette J. A.; Griffiths, Lyn R.; Ikram, M. Arfan; Wessman, Maija; Kaunisto, Mari; Hrafnsdottir, Maria G.; Hiekkala, Marjo; Järvelin, Marjo-Riitta; Dichgans, Martin; Pirinen, Matti; Kallela, Mikko; Kurki, Mitja; Chalmer, Mona A.; Pedersen, Nancy; Sveinsson, Olafur A.; Raitakari, Olli; Gormley, Padhraig; Pozo-Rosich, Patricia; Palta, Priit; Malik, Rainer; Kajanne, Risto; Børte, Sigrid; Magnusson, Sigurdur H.; Lehtimäki, Terho; Hansen, Thomas F; Thorgeirsson, Thorgeir E.; Freilinger, Tobias; Kurth, Tobias; Esko, Tonu; Anttila, Verneri; Artto, Ville; Wu, Bai-Hua; Shi, Miao; Dong, Ming (Peer reviewed; Journal article, 2024)
      Statins are thought to have positive effects on migraine but existing data are inconclusive. We aimed to evaluate the causal effect of such drugs on migraines using Mendelian randomization. We used four types of genetic ...

    • Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants 

      Winsvold, Bendik K S; Bettella, Francesco; Witoelar, A; Anttila, Verneri; Gormley, Padhraig; Kurth, Tobias; Terwindt, Gisela M; Freilinger, Tobias; Frei, Oleksandr; Shadrin, Alexey A.; Wang, Yunpeng; Dale, Anders; Van Den Maagdenberg, Arn M.J.M.; Chasman, Daniel I; Nyholt, Dale R; Palotie, Aarno; Andreassen, Ole Andreas; Zwart, John-Anker (Journal article; Peer reviewed, 2017)
      Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little is known of its vascular basis. In epidemiological studies migraine is associated with an increased risk of cardiovascular ...