• Circulating concentrations of biomarkers and metabolites related to Vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations 

      Midttun, Øivind; Theofylaktopoulou, Despoina; Mccann, Adrian; Fanidi, Anouar; Muller, David C.; Meyer, Klaus; Ulvik, Arve; Zheng, Wei; Shu, Xiao-Ou; Xiang, Yong-Bing; Prentice, Ross; Thomson, Cynthia A.; Pettinger, Mary; Giles, Graham G.; Hodge, Allison; Cai, Qiuyin; Blot, William J.; Wu, Jie; Johansson, Mikael; Hultdin, Johan; Grankvist, Kjell; Stevens, Victoria L.; McCullough, Marjorie L.; Weinstein, Stephanie J.; Albanes, Demetrius; Langhammer, Arnulf; Hveem, Kristian; Næss, Marit; Sesso, Howard D.; Gaziano, J. Michael; Buring, Julie E.; Lee, I-Min; Severi, Gianluca; Zhang, Xuehong; Han, Jiali; Stampfer, Meir J.; Smith-Warner, Stephanie A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loic; Yuan, Jian-Min; Butler, Lesley M.; Koh, Woon-Puay; Wang, Renwei; Gao, Yu-Tang; Ericson, Ulrika; Sonestedt, Emily; Ziegler, Regina G.; Freedman, Neal D.; Visvanathan, Kala; Jones, Miranda R.; Relton, Caroline; Brennan, Paul; Johansson, Mattias; Ueland, Per Magne (Journal article; Peer reviewed, 2017)
      Background: Circulating concentrations of biomarkers that are related to vitamin status vary by factors such as diet, fortification, and supplement use. Published biomarker concentrations have also been influenced by the ...
    • Circulating cotinine concentrations and lung cancer risk in the Lung Cancer Cohort Consortium (LC3) 

      Larose, Tricia L; Guida, Florence; Anouar, Fanidi; Langhammer, Arnulf; Hveem, Kristian; Stevens, Victoria L.; Jacobs, Eric J.; Smith-Warner, Stephanie A.; Giovannucci, Edward; Albanes, Demetrius; Weinstein, Stephanie J.; Freedman, Neal D.; Prentice, Ross; Pettinger, Mary; Thomson, Cynthia A.; Cai, Qiuyin; Wu, Jie; Blot, William J; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loic; Wilkens, Lynne R.; Haiman, Christopher A.; Zhang, Xuehong; Stampfer, Meir J; Hodge, Allison M.; Giles, Graham G.; Severi, Gianluca; Johansson, Mikael; Grankvist, Kjell; Wang, Renwei; Yuan, Jian-Min; Gao, Yu-Tang; Koh, Woon-Puay; Shu, Xiao-Ou; Zheng, Wei; Xiang, Yong-Bing; Li, Honglan; Lan, Qing; Visvanathan, Kala; Hoffman Bolton, Judith; Ueland, Per Magne; Midttun, Øivind; Caporaso, Neil; Purdue, Mark; Sesso, Howard D.; Buring, Julie E.; Lee, I-Min; Gaziano, J. Michael; Manjer, Jonas; Brunnström, Hans; Brennan, Paul; Johansson, Mattias (Journal article; Peer reviewed, 2018)
      Background Self-reported smoking is the principal measure used to assess lung cancer risk in epidemiological studies. We evaluated if circulating cotinine—a nicotine metabolite and biomarker of recent tobacco exposure—provides ...
    • Circulating markers of cellular immune activation in pre-diagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3) 

      Huang, Joyce Yongxu; Larose, Tricia L; Luu, Hung N; Wang, Renwei; Fanidi, Anouar; Alcala, Karine; Stevens, Victoria L.; Weinstein, Stephanie J.; Albanes, Demetrius; Caporaso, Neil E.; Purdue, Mark P.; Ziegler, Regina G.; Freedman, Neal D.; Lan, Qing; Prentice, Ross L.; Pettinger, Mary; Thomson, Cynthia A.; Cai, Qiuyin; Wu, Jie; Blot, William J.; Shu, Xiao-Ou; Zheng, Wei; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loïc; Wilkens, Lynn R; Haiman, Christopher A.; Zhang, Xuehong; Stampfer, Meir J.; Han, Jiali; Giles, Graham G.; Hodge, Allison M.; Severi, Gianluca; Johansson, Mikael; Grankvist, Kjell; Langhammer, Arnulf; Hveem, Kristian; Xiang, Yong-Bing; Li, Hong-Lan; Gao, Yu-Tang; Visvanathan, Kala; Ueland, Per Magne; Midttun, Øivind; Ulvik, Arve; Buring, Julie E.; Lee, I-Min; Sesso, Howard D.; Gaziano, J. Michael; Manjer, Jonas; Relton, Caroline; Koh, Woon-Puay; Brennan, Paul; Johansson, Mattias; Yuan, Jian-Min (Journal article; Peer reviewed, 2019)
      Cell‐mediated immune suppression may play an important role in lung carcinogenesis. We investigated the associations for circulating levels of tryptophan, kynurenine, kynurenine:tryptophan ratio (KTR), quinolinic acid (QA) ...
    • Genome-wide association study identifies multiple risk loci for renal cell carcinoma 

      Scelo, Ghislaine; Purdue, Mark P.; Brown, Kevin M.; Johansson, Mattias; Wang, Zhaoming; Eckel-Passow, Jeanette E.; Ye, Yuanqing; Hofmann, Jonathan N.; Choi, Jiyeon; Foll, Matthieu; Gaborieau, Valerie; Machiela, Mitchell J.; Colli, Leandro M.; Li, Peng; Sampson, Joshua N.; Abedi-Ardekani, Behnoush; Besse, Celine; Blanche, Helene; Boland, Anne; Burdette, Laurie; Chabrier, Amelie; Durand, Geoffroy; Le Calvez-Kelm, Florence; Prokhortchouk, Egor; Robinot, Nivonirina; Skryabin, Konstantin G.; Wozniak, Magdalena B.; Yeager, Meredith; Basta-Jovanovic, Gordana; Dzamic, Zoran; Foretova, Lenka; Holcatova, Ivana; Janout, Vladimir; Mates, Dana; Mukeriya, Anush; Rascu, Stefan; Zaridze, David; Bencko, Vladimir; Cybulski, Cezary; Fabianova, Eleonora; Jinga, Viorel; Lissowska, Jolanta; Lubinski, Jan; Navratilova, Marie; Rudnai, Peter; Szeszenia-Dabrowska, Neonila; Benhamou, Simone; Cancel-Tassin, Geraldine; Cussenot, Olivier; Baglietto, Laura; Boeing, Heiner; Khaw, Kay-Tee; Weiderpass, Elisabete; Ljungberg, Börje; Sitaram, Raviprakash T.; Bruinsma, Fiona; Jordan, Susan J.; Severi, Gianluca; Winship, Ingrid; Hveem, Kristian; Vatten, Lars Johan; Fletcher, Tony; Koppova, Kvetoslava; Larsson, Susanna C.; Wolk, Alicja; Banks, Rosamonde E.; Selby, Peter J.; Easton, Douglas F.; Pharoah, Paul; Andreotti, Gabriella; Freeman, Laura E Beane; Koutros, Stella; Albanes, Demetrius; Männistö, Satu; Weinstein, Stephanie; Clark, Peter E.; Edwards, Todd L.; Lipworth, Loren; Gapstur, Susan M.; Stevens, Victoria L.; Carol, Hallie; Freedman, Matthew L.; Pomerantz, Mark M.; Cho, Eunyoung; Kraft, Peter; Preston, Mark A.; Wilson, Kathryn M.; Gaziano, J. Michael; Sesso, Howard D.; Black, Amanda; Freedman, Neal D.; Huang, Wen-Yi; Anema, John G.; Kahnoski, Richard J.; Lane, Brian R.; Noyes, Sabrina L.; Petillo, David; Teh, Bin Tean; Peters, Ulrike; White, Emily; Anderson, Garnet L.; Johnson, Lisa; Luo, Juhua; Buring, Julie; Lee, I-Min; Chow, Wong-Ho; Moore, Lee E.; Wood, Christopher; Eisen, Timothy; Henrion, Marc; Larkin, James; Barman, Poulami; Leibovich, Bradley C.; Choueiri, Toni K.; Lathrop, G. Mark; Rothman, Nathaniel; Deleuze, Jean-Francois; McKay, James D.; Parker, Alexander S.; Wu, Xifeng; Houlston, Richard S.; Brennan, Paul; Chanock, Stephen J. (Journal article; Peer reviewed, 2017)
      Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing ...
    • Low free testosterone and prostate cancer risk: A collaborative analysis of 20 prospective studies 

      Watts, Eleanor L.; Appleby, Paul N.; Perez-Cornago, Aurora; Bueno-De-Mesquita, Hendrik Bastiaan; Chan, June M.; Chen, Chu; Cohn, Barbara A.; Cook, Michael B.; Flicker, Leon; Freedman, Neal D.; Giles, Graham G.; Giovannucci, Edward; Gislefoss, Randi Elin; Hankey, Graeme J.; Kaaks, Rudolf; Knekt, Paul; Kolonel, Laurence N.; Kubo, Tatsuhiko; Le Marchand, Loïc; Luben, Robert N.; Luostarinen, Tapio; Männistö, Satu; Metter, E. Jeffrey; Mikami, Kazuya; Milne, Roger L.; Ozasa, Kotaro; Platz, Elizabeth A.; Quirós, José Ramón; Rissanen, Harri; Sawada, Norie; Stampfer, Meir; Stanczyk, Frank Z.; Stattin, Pär; Tamakoshi, Akiko; Tangen, Catherine M.; Thompson, Ian M.; Tsilidis, Konstantinos K.; Tsugane, Shoichiro; Ursin, Giske; Vatten, Lars Johan; Weiss, Noel S.; Yeap, Bu B.; Allen, Naomi E.; Key, Timothy J.; Travis, Ruth C. (Journal article; Peer reviewed, 2018)
      Background Experimental and clinical evidence implicates testosterone in the aetiology of prostate cancer. Variation across the normal range of circulating free testosterone concentrations may not lead to changes in ...
    • The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study 

      Johansson, Mattias; Carreras-Torres, Robert; Scelo, Ghislaine; Purdue, Mark P.; Mariosa, Daniela; Muller, David C.; Timpson, Nicholas J.; Haycock, Philip C.; Brown, Kevin M.; Wang, Zhaoming; Ye, Yuanqing; Hofmann, Jonathan N.; Foll, Matthieu; Gaborieau, Valerie; Machiela, Mitchell J.; Colli, Leandro M.; Li, Peng; Garnier, Jean-Guillaume; Blanche, Helene; Boland, Anne; Burdette, Laurie; Prokhortchouk, Egor; Skryabin, Konstantin G.; Yeager, Meredith; Radojevic-Skodric, Sanja; Ognjanovic, Simona; Foretova, Lenka; Holcatova, Ivana; Janout, Vladimir; Mates, Dana; Mukeriya, Anush; Rascu, Stefan; Zaridze, David; Bencko, Vladimir; Cybulski, Cezary; Fabianova, Eleonora; Jinga, Viorel; Lissowska, Jolanta; Lubinski, Jan; Navratilova, Marie; Rudnai, Peter; Benhamou, Simone; Cancel-Tassin, Geraldine; Cussenot, Olivier; Weiderpass, Elisabete; Ljungberg, Börje; Tumkur Sitaram, Raviprakash; Häggström, Christel; Bruinsma, Fiona; Jordan, Susan J.; Severi, Gianluca; Winship, Ingrid; Hveem, Kristian; Vatten, Lars Johan; Fletcher, Tony; Larsson, Susanna C.; Wolk, Alicja; Banks, Rosamonde E.; Selby, Peter J.; Easton, Douglas F.; Andreotti, Gabriella; Beane Freeman, Laura E.; Koutros, Stella; Männistö, Satu; Weinstein, Stephanie; Clark, Peter E.; Edwards, Todd L.; Lipworth, Loren; Gapstur, Susan M.; Stevens, Victoria L.; Carol, Hallie; Freedman, Matthew L.; Pomerantz, Mark M.; Cho, Eunyoung; Wilson, Kathryn M.; Gaziano, J. Michael; Sesso, Howard D.; Freedman, Neal D.; Parker, Alexander S.; Eckel-Passow, Jeanette E.; Huang, Wen-Yi; Kahnoski, Richard J.; Lane, Brian R.; Noyes, Sabrina L.; Petillo, David; Teh, Bin Tean; Peters, Ulrike; White, Emily; Anderson, Garnet L.; Johnson, Lisa; Luo, Juhua; Buring, Julie; Lee, I-Min; Chow, Wong-Ho; Moore, Lee E.; Eisen, Timothy; Henrion, Marc; Larkin, James; Barman, Poulami; Leibovich, Bradley C.; Choueiri, Toni K.; Lathrop, G. Mark; Deleuze, Jean-François; Gunter, Marc; McKay, James D.; Wu, Xifeng; Houlston, Richard S.; Chanock, Stephen J.; Relton, Caroline; Richards, J. Brent; Martin, Richard M.; Davey Smith, George; Brennan, Paul (Journal article; Peer reviewed, 2019)
      Background Several obesity-related factors have been associated with renal cell carcinoma (RCC), but it is unclear which individual factors directly influence risk. We addressed this question using genetic markers as ...
    • Timing of HPV16-E6 antibody seroconversion before OPSCC: Findings from the HPVC3 consortium 

      Kreimer, Aimée R.; Ferreiro-Iglesias, Aida; Nygård, Mari; Bender, Noemi; Schroeder, Lea; Hildesheim, Alan; Robbins, Hilary A.; Pawlita, Michael; Langseth, Hilde; Schlecht, Nicolas F.; Tinker, Lesley Fels; Agalliu, Ilir; Smoller, Sylvia W.; Ness-Jensen, Eivind; Hveem, Kristian; D'Souza, Gypsyamber; Visvanathan, Kala; May, Betty; Ursin, Giske; Weiderpass, Elisabete; Giles, Graham G.; Milne, Roger L.; Cai, Qiuyin; Blot, William J.; Zheng, Wei; Weinstein, Stephanie J.; Albanes, Demetrius; Brenner, Nicole; Hoffman-Bolton, Judith; Kaaks, Rudolf; Barricarte, Aurelio; Tjønneland, Anne; Sacerdote, Carlotta; Trichopoulou, Antonia; Vermeulen, Roel C.H.; Huang, Wen-Yi; Freedman, Neal D.; Brennan, Paul J.; Waterboer, Tim; Johansson, Mattias (Journal article; Peer reviewed, 2019)
      Background Human papillomavirus type 16 (HPV16)-E6 antibodies are detectable in peripheral blood before diagnosis in the majority of HPV16-driven oropharyngeal squamous cell carcinoma (OPSCC), but the timing of seroconversion ...