• Ancient and modern stickleback genomes reveal the demographic constraints on adaptation 

      Kirch, Melanie; Romundset, Anders; Gilbert, Marcus Thomas Pius; Jones, Felicity C.; Foote, Andrew (Peer reviewed; Journal article, 2021)
      Adaptation is typically studied by comparing modern populations with contrasting environments. Individuals persisting in the ancestral habitat are typically used to represent the ancestral founding population; however, it ...
    • Ancient dolphin genomes reveal rapid repeated adaptation to coastal waters 

      Louis, Marie; Korlević, Petra; Nykänen, Milaja; Archer, Frederick; Berrow, Simon; Brownlow, Andrew; Lorenzen, Eline D.; O’Brien, Joanne; Post, Klaas; Racimo, Fernando; Rogan, Emer; Rosel, Patricia E.; Sinding, Mikkel Holger Strander; van der Es, Henry; Wales, Nathan; Fontaine, Michael C.; Gaggiotti, Oscar E.; Foote, Andrew (Peer reviewed; Journal article, 2023)
      Parallel evolution provides strong evidence of adaptation by natural selection due to local environmental variation. Yet, the chronology, and mode of the process of parallel evolution remains debated. Here, we harness the ...
    • Building genomic infrastructure: Sequencing platinum-standard reference-quality genomes of all cetacean species. 

      Morin, Phillip A.; Alexander, Alana; Blaxter, Mark; Caballero, Susana; Fedrigo, Olivier; Fontaine, Michaël C.; Foote, Andrew; Kuraku, Shigehiro; Maloney, Brigid; McCarthy, Morgan; McGowen, Michael; Mountcastle, Jacquelyn; Nery, Mariana; Olsen, Morten Tange; Rosel, Patricia; Jarvis, Erich D. (Journal article; Peer reviewed, 2020)
    • The genome sequence of the killer whale, Orcinus orca (Linnaeus, 1758) 

      Foote, Andrew; Bunskoek, Paulien; Sanger, Wellcome (Peer reviewed; Journal article, 2022)
      We present a genome assembly from an individual female Orcinus orca (the killer whale; Chordata; Mammalia; Artiodactyla; Delphinidae). The genome sequence is 2.65 gigabases in span. The majority of the assembly (93.76%) ...
    • Inference of natural selection from ancient DNA 

      Dehasque, Marianne; Ávila-Arcos, María C; Díez-del-Molino, David; Fumagalli, Matteo; Guschanski, Katerina; Lorenzen, Eline D.; Malaspinas, Anna-Sapfo; Marques-Bonet, Tomas; Martin, Michael David; Murray, Gemma G.R.; Papadopulos, Alexander; Therkildsen, Nina Overgaard; Wegmann, Daniel; Dalén, Love; Foote, Andrew (Peer reviewed; Journal article, 2020)
      Evolutionary processes, including selection, can be indirectly inferred based on patterns of genomic variation among contemporary populations or species. However, this often requires unrealistic assumptions of ancestral ...
    • Phylogenomics and species delimitation for effective conservation of manta and devil rays 

      Hosegood, Jane; Humble, Emily; Ogden, Rob; de Bruyn, Mark; Creer, Simon; Stevens, Guy; Abudaya, Mohammed; Bassos-Hull, Kim; Bonfil, Ramon; Fernando, Daniel; Foote, Andrew; Hipperson, Helen; Jabado, Rima; Kaden, Jennifer; Moazzam, Muhammad; Peel, Lauren; Pollett, Stephen; Ponzo, Alessandro; Poortvliet, Marloes; Salah, Jehad; Senn, Helen; Stewart, Joshua; Witner, Sabine; Wintner, Sabine; Carvalho, Gary (Peer reviewed; Journal article, 2020)
      Practical biodiversity conservation relies on delineation of biologically meaningful units. Manta and devil rays (Mobulidae) are threatened worldwide, yet morphological similarities and a succession of recent taxonomic ...
    • Rapid Parallel Adaptation to Anthropogenic Heavy Metal Pollution 

      Papadopulos, Alexander; Helmstetter, A.; Osborne, Owen; Comeault, Aaron; Wood, Daniel; Straw, Edward; Mason, Laurence; Fay, Michael F; Foote, Andrew; Parker, Joe; Dunning, Luke; Smith, Rhian; Lighten, Jackie (Peer reviewed; Journal article, 2021)
      The impact of human-mediated environmental change on the evolutionary trajectories of wild organisms is poorly understood. In particular, species’ capacities to adapt rapidly (in hundreds of generations or less), reproducibly ...
    • Runs of homozygosity in killer whale genomes provide a global record of demographic histories 

      Foote, Andrew; Hooper, Rebecca; Alexander, Alana; Baird, Robin; Baker, Scott; Ballance, Lisa; Barlow, Jay; Brownlow, Andrew; Collins, Tim; Constantine, Rochelle; Rosa, Luciano Dalla; Davison, Nicholas J.; Durban, John; Esteban, Ruth; Excoffier, Laurent; Forney, Karin A.; Gerrodette, Tim; Gilbert, Marcus Thomas Pius; Guinet, Christophe; Hanson, M. Bradley; Li, Songhai; Martin, Sarah; Martin, Michael David; Robertson, Kelly M.; Samarra, Filipa I.P.; de Stephanis, Renaud; Tavares, Sara B.; Tixier, Paul; Totterdell, John A.; Wade, Paul; Wolf, Jochen B.W.; Fan, Guangyi; Zhang, Yaolei; Morin, Phillip A. (Peer reviewed; Journal article, 2021)
      Runs of homozygosity (ROH) occur when offspring inherit haplotypes that are identical by descent from each parent. Length distributions of ROH are informative about population history; specifically, the probability of ...