Blar i NTNU Open på forfatter "Fladvad, Torill"

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    • Is there a genetic cause of appetite loss? - An explorative study in 1853 cancer patients 

      Solheim, Tora Skeidsvoll; Fayers, Peter; Fladvad, Torill; Tan, Ben; Skorpen, Frank; Fearon, Kenneth C.; Baracos, Vickie; Klepstad, Pål; Strasser, Florian; Kaasa, Stein (Journal article; Peer reviewed, 2012)
      Background Appetite loss has a major impact on cancer patients. It is exceedingly prevalent, is a prognostic indicator and is associated with inferior quality of life. Cachexia is a multi‐factorial syndrome defined by a ...

    • P-selectin genotype is associated with the development of cancer cachexia 

      Tan, Benjamin HL; Fladvad, Torill; Braun, TP; Vigano, Antonio A.L.; Strasser, Florian; Deans, DAC; Skipworth, R.J.; Skeidsvoll, Tora Lång; Damaraju, S; Ross, JA; Kaasa, Stein; Marks, DL; Baracos, Vickie; Skorpen, Frank; Fearon, Kenneth C. (Journal article; Peer reviewed, 2012)
      The variable predisposition to cachexia may, in part, be due to the interaction of host genotype. We analyzed 129 single nucleotide polymorphisms (SNPs) in 80 genes for association with cachexia based on degree of weight ...

    • Pain treatment in patients with advanced cancer disease:the impact of genetic variability 

      Fladvad, Torill (Doktoravhandlinger ved NTNU, 1503-8181; 2013:301, Doctoral thesis, 2013)
      Smertebehandling hos pasienter med avansert kreftsykdom kan være utfordrende. Pasientgruppen kjennetegnes ved relativt høy gjennomsnittsalder, pasientene har gjerne flere sykdommer og symptomer som må behandles samtidig, ...

    • The N-Terminally Truncated µ3 and µ3-Like Opioid Receptors Are Transcribed from a Novel Promoter Upstream of Exon 2 in the Human OPRM1 Gene 

      Andersen, Sonja; Baar, Cecilie Christensen; Fladvad, Torill; Laugsand, Eivor Alette; Skorpen, Frank (Journal article; Peer reviewed, 2013)
      The human µ opioid receptor gene, OPRM1, produces a multitude of alternatively spliced transcripts encoding full-length or truncated receptor variants with distinct pharmacological properties. The majority of these transcripts ...