• Enantioselective chromatographic separation and lipase catalyzed asymmetric resolution of biologically important chiral amines 

      El-Behairy, Mohammed Farrag; Hassan, Rasha M.; Sundby, Eirik (Peer reviewed; Journal article, 2021)
      Cyanoacetamides are vital synthons in synthetic organic chemistry. However, methods to enantiopure cyanoacetamides have not yet been well explored. In this work, the preparation of cyanoacetamide synthons RS-(1a–4a) or ...
    • Lipase Catalysed Kinetic Resolution of Stiripentol 

      Jacobsen, Elisabeth Egholm; Anthonsen, Thorleif; El-Behairy, Mohammed Farrag; Sundby, Eirik; Aboul-Enein, Mohamed Nabil; Attia, Mohamed Ibrahim; El-Azzouny, Aida Abd El-Sattar; Amin, Kamilia M.; Abdel-Rehim, Mohamed (Journal article; Peer reviewed, 2012)
      Kinetic resolution of rac-Stiripentol, catalysed by lipase A from Candida antarctica by esterification with vinyl butanoate was performed with an E-value of 24. This allowed isolation of (3S)-Stiripentol with an ee of 86 ...
    • One-step lipase-catalysed preparation of eslicarbazepine 

      El-Behairy, Mohammed Farrag; Sundby, Eirik (Peer reviewed; Journal article, 2016)
      The antiepileptic eslicarbazepine (S-licarbazepine) has been prepared in one step from its racemic form RS-licarbazepine via lipase catalysed kinetic resolution. A novel stereoselective simultaneous HPLC separations of ...