Blar i NTNU Open på forfatter "Eken, Torsten"
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Biphasic release of the alarmin high mobility group box 1 protein early after trauma predicts poor clinical outcome
Ottestad, William Arne; Rognes, Ingrid Nygren; Pischke, Søren; Mollnes, Tom Eirik; Andersson, Ulf; Eken, Torsten (Journal article; Peer reviewed, 2019)Objectives: The causal role of the prototype alarmin high mobility group box 1 protein in systemic inflammation and remote organ injury after trauma and shock is established in animal models but not in humans. Our aim ... -
Forskjeller i mortalitet hos traumepasienter
Wisborg, Torben; Dehli, Trond; Eken, Torsten; Brattebø, Guttorm; Johnsen, Lars Gunnar (Peer reviewed; Journal article, 2023)Mortaliteten blant norske traumepasienter i perioden 2015–18 var på linje med de beste resultatene fra andre land, men fortsatt fant vi regionale forskjeller og forskjeller mellom sykehusnivåer. Selv om resultatene er bra, ... -
Increased complement activation 3 to 6 h after trauma is a predictor of prolonged mechanical ventilation and multiple organ dysfunction syndrome: a prospective observational study
Rognes, Ingrid Nygren; Pischke, Søren Erik; Ottestad, William; Røislien, Jo; Berg, Jens Petter; Johnson, Christina; Eken, Torsten; Mollnes, Tom Eirik (Journal article; Peer reviewed, 2021)Background - Complement activation is a central mechanism in systemic inflammation and remote organ dysfunction following major trauma. Data on temporal changes of complement activation early after injury is largely missing. ... -
Injury Prevention and long-term Outcomes following Trauma - The IPOT project: a protocol for prospective nationwide registry-based studies in Norway
Stenehjem, Jo Steinson; Røise, Olav; Nordseth, Trond; Clausen, Thomas; Natvig, Bård; Skurtveit, Svetlana Ondrasova; Eken, Torsten; Kristiansen, Thomas; Gran, Jon Michael; Rosseland, Leiv Arne (Peer reviewed; Journal article, 2021)Introduction Traumatic injuries constitute a major cause of mortality and morbidity. Still, the public health burden of trauma in Norway has not been characterised using nationwide registry data. More knowledge is warranted ... -
Mortality after hospital admission for trauma in Norway: A retrospective observational national cohort study
Dehli, Trond; Wisborg, Torben; Johnsen, Lars Gunnar; Brattebø, Guttorm; Eken, Torsten (Peer reviewed; Journal article, 2023)Background National quality data for trauma care in Norway have not previously been reported. We have therefore assessed crude and risk-adjusted 30-day mortality in trauma cases after primary hospital admission on national ... -
Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study
Sundnes, Olav; Ottestad, William Arne; Schjalm, Camilla; Lundbäck, Peter; La Cour Poulsen, Lars; Mollnes, Tom Eirik; Haraldsen, Guttorm; Eken, Torsten (Journal article; Peer reviewed, 2021)Background Alarmins are considered proximal mediators of the immune response after tissue injury. Understanding their biology could pave the way for development of new therapeutic targets and biomarkers in human disease, ...