Browsing NTNU Open by Author "Eckelt, Sarah"

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    • Potent and selective EGFR inhibitors based on 5-aryl-7H-pyrrolopyrimidin-4-amines 

      Reiersølmoen, Ann Christin; Aarhus, Thomas Ihle; Eckelt, Sarah; Nørsett, Kristin Gabestad; Sundby, Eirik; Hoff, Bård Helge (Journal article; Peer reviewed, 2019)
      The epidermal growth factor receptor represents an important target in cancer therapy, and low molecular weight inhibitors based on quinazolines have reached the marked. Herein we report on a new scaffold, 5-aryl-7H-pyrr ...