Browsing NTNU Open by Author "Dille, Morten Johnsen"
Now showing items 1-7 of 7
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Bioactively filled gelatin gels; challenges and opportunities
Dille, Morten Johnsen; Hattrem, Magnus Nergård; Draget, Kurt Ingar (Journal article; Peer reviewed, 2016)Soft, chewable gelatin matrices represent an excellent alternative to traditional oral administration forms (tablets, soft and hard capsules) for pharma- and nutraceuticals; especially for the pediatric and geriatric ... -
Gels and emulsions in oral delivery; Optimization of texture, stability and bioavailability in selected systems
Dille, Morten Johnsen (Doctoral theses at NTNU;2021:165, Doctoral thesis, 2021)Dietary supplements and pharmaceuticals are commonly taken orally as tablets or capsules. However, a significant fraction of the population experience discomfort when swallowing such dosage forms, which can result in poor ... -
Gels and gelled emulsions prepared by acid-induced gelation of mixtures of faba bean (Vicia faba) protein concentrate and λ-carrageenan
Dille, Morten Johnsen; Knutsen, Svein Halvor; Draget, Kurt Ingar (Journal article, 2022)In this study, gels were successfully prepared at room temperature from mixtures of dry fractionated faba bean protein concentrate (FPC) and λ-carrageenan (λ-CGN), through acidification with glucono-δ-lactone (GDL). At ... -
Ibuprofen-in-cyclodextrin-in-W/O/W emulsion - Improving the initial and long-term encapsulation efficiency of a model active ingredient.
Hattrem, Magnus; Kristiansen, Kåre Andre; Aachmann, Finn Lillelund; Dille, Morten Johnsen; Draget, Kurt Ingar (Journal article; Peer reviewed, 2015)A challenge in formulating water-in-oil-in-water (W/O/W) emulsions is the uncontrolled release of the encapsulated compound prior to application. Pharmaceuticals and nutraceuticals usually have amphipathic nature, which ... -
Mechanical properties of 67NR tumours are broadly independent of the immune status of the host mouse
Nordgård, Catherine Taylor; Rao, Shalini Vasudev; Dille, Morten Johnsen; Steigedal, Tonje S.; Draget, Kurt Ingar (Journal article; Peer reviewed, 2017)Tumour stiffness is increasingly seen as a clinically relevant parameter, with increased stiffness being linked to poorer prognosis, but it is also one that is not inherently easy to measure either in vivo or ex vivo. We ... -
Soft, chewable gelatin-based pharmaceutical oral formulations: a technical approach
Dille, Morten Johnsen; Hattrem, Magnus Nergård; Draget, Kurt Ingar (Journal article; Peer reviewed, 2018) -
The Relative Bioavailability of Ibuprofen After Administration With a Novel Soft Chewable Drug Formulation
Hattrem, Magnus Nergård; Dille, Morten Johnsen; Seternes, Tore; Ege, Thorfinn; Draget, Kurt Ingar (Journal article; Peer reviewed, 2017)The first aim of the present study was to evaluate the bioavailability of ibuprofen dispersed in a novel soft chewable formulation compared with a traditional ibuprofen tablet; its second was to map the quality of taste ...