Browsing NTNU Open by Author "Denham, Sean Dexter"

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    • Multi-omic detection of Mycobacterium leprae in archaeological human dental calculus 

      Fotakis, Anna K.; Denham, Sean Dexter; Mackie, Meaghan; Orbegozo, Miren Iraeta; Mylopotamitaki, Dorothea; Gopalakrishnan, Shyam; Sicheritz-Pontén, Thomas; Olsen, Jesper V.; Cappellini, Enrico; Zhang, Guojie; Christophersen, Axel; Gilbert, Thomas; Vågene, Åshild J (Peer reviewed; Journal article, 2020)
      Mineralized dental plaque (calculus) has proven to be an excellent source of ancient biomolecules. Here we present a Mycobacterium leprae genome (6.6-fold), the causative agent of leprosy, recovered via shotgun sequencing ...

    • The population genomic legacy of the second plague pandemic 

      Gopalakrishnan, Shyam; Ebenesersdottir, S.Sunna; Lundstrøm, Inge K.C.; Turner-Walker, Gordon; Moore, Kristjan H.S.; Luisi, Pierre; Magaryan, Ashot; Martin, Michael D.; Ellegaard, Martin Rene; Magnusson, Olafur T.; Sigurdsson, Asgeir; Snorradóttir, Steinunn; Magnúsdóttir, Droplaug N.; Laffoon, Jason E.; van Dorp, Lucy; Liu, Xiaodong; Moltke, Ida; Avila-Arcos, María C.; Schraiber, Joshua G.; Rasmussen, Simon; Juan, David; Galabert, Pere; De-Dios, Toni; Fotakis, Anna K.; Iraeta-Orbegozo, Miren; Vågene, Åshild J.; Denham, Sean Dexter; Christophersen, Axel; Stenøien, Hans K.; Vieira, Filipe G.; Liu, Shanlin; Günther, Torsten; Kivisild, Toomas; Moseng, Ole Georg; Skar, Birgitte; Cheung, Christina; Sandoval-Velasco, Marcela; Wales, Nathan; Schroeder, Hannes; Campos, Paula F.; Gudmundsdottir, Valdis B; Sicheritz - Ponten, Thomas; Petersen, Bent; Halgunset, Jostein; Gilbert, Edmund; Cavalleri, Gianpiero L.; Hovig, Eivind; Kockum, Ingrid; Olsson, Tomas; Alfredsson, Lars; Hansen, Thomas F.; Werge, Thomas; Willerslev, Eske; Balloux, Francois; Marquès-Bonet, Tomás; Lalueza-Fox, Carles; Nielsen, Rasmus; Stefánsson, Kári; Helgason, Agnar; Gilbert, Thomas P. (Peer reviewed; Journal article, 2022)
      Human populations have been shaped by catastrophes that may have left long-lasting signatures in their genomes. One notable example is the second plague pandemic that entered Europe in ca. 1,347 CE and repeatedly returned ...