Browsing NTNU Open by Author "Davies, Catharina De Lange"
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Contact-mediated intracellular delivery of hydrophobic drugs from polymeric nanoparticles
Snipstad, Sofie; Westrøm, Sara; Mørch, Ýrr Asbjørg; Afadzi, Mercy; Åslund, Andreas; Davies, Catharina De Lange (Journal article; Peer reviewed, 2014)Encapsulation of drugs in nanoparticles can enhance the accumulation of drugs in tumours, reduce toxicity toward healthy tissue, and improve pharmacokinetics compared to administration of free drug. To achieve efficient ... -
Nonlinear optical microscopy of early stage (ICRS Grade-I) osteoarthritic human cartilage
Kumar, Rajesh; Grønhaug, Kirsten Marie; Davies, Catharina De Lange; Drogset, Jon Olav; Lilledahl, Magnus Borstad (Journal article; Peer reviewed, 2015) -
Quantification and Qualitative Effects of Different PEGylations on Poly(butyl cyanoacrylate) Nanoparticles
Åslund, Andreas; Sulheim, Einar; Snipstad, Sofie; von Haartman, Eva; Baghirov, Habib; Starr, Nichola; Løvmo, Mia Kvåle; Lelu, Sylvie; Scurr, David; Davies, Catharina De Lange; Schmid, Ruth; Mørch, Yrr Asbjørg (Journal article, 2017)Protein adsorption on nanoparticles (NPs) used in nanomedicine leads to opsonization and activation of the complement system in blood, which substantially reduces the blood circulation time of NPs. The most commonly used ... -
Quantitative 3-D colocalization analysis as a tool to study the intracellular trafficking and dissociation of pDNA-chitosan polyplexes
Reitan, Nina Kristine; Sporsheim, Bjørnar; Bjørkøy, Astrid; Strand, Sabina P.; Davies, Catharina De Lange (Journal article; Peer reviewed, 2012)Multichannel microscopy is frequently used to study intermolecular interactions and spatial relationships between biomolecules and organelles or vesicles in cells. Based on multichannel images, quantitative colocalization ... -
Quantitative characterization of articular cartilage using Mueller matrix imaging and multiphoton microscopy
Ellingsen, Pål Gunnar; Lilledahl, Magnus Borstad; Aas, Lars Martin Sandvik; Davies, Catharina De Lange; Kildemo, Morten (Journal article; Peer reviewed, 2011)The collagen meshwork in articular cartilage of chicken knee is characterized using Mueller matrix imaging and multiphoton microscopy. Direction and degree of dispersion of the collagen fibers in the superficial layer are ... -
Single Cell Confocal Raman Spectroscopy of Human Osteoarthritic Chondrocytes: A Preliminary Study
Kumar, Rajesh; Singh, Gajendra Pratap; Grønhaug, Kirsten Marie; Afseth, Nils Kristian; Davies, Catharina De Lange; Drogset, Jon Olav; Lilledahl, Magnus Borstad (Journal article; Peer reviewed, 2015)A great deal of effort has been focused on exploring the underlying molecular mechanism of osteoarthritis (OA) especially at the cellular level. We report a confocal Raman spectroscopic investigation on human osteoarthritic ...