Blar i NTNU Open på forfatter "Datsomor, Alex Kojo"
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CRISPR/Cas9-mediated editing of Δ5 and Δ6 desaturases impairs Δ8-desaturation and docosahexaenoic acid synthesis in Atlantic salmon (Salmo salar L.)
Datsomor, Alex Kojo; Olsen, Rolf Erik; Madaro, Angelico; Bones, Atle M.; Edvardsen, Rolf Brudvik; Wargelius, Anna; Winge, Per (Journal article; Peer reviewed, 2019)The in vivo functions of Atlantic salmon fatty acyl desaturases (fads2), Δ6fads2-a, Δ6fads2-b, Δ6fads2-c and Δ5fads2 in long chain polyunsaturated fatty acid (LC-PUFA) synthesis in salmon and fish in general remains to be ... -
Molecular Regulation of Biosynthesis of Long Chain Polyunsaturated Fatty Acids in Atlantic Salmon
Datsomor, Alex Kojo; Gillard, Gareth Benjamin; Jin, Yang; Olsen, Rolf Erik; Sandve, Simen Rød (Peer reviewed; Journal article, 2022)Salmon is a rich source of health-promoting omega-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA), such as eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3). The LC-PUFA biosynthetic pathway ... -
Targeted mutagenesis of Δ5 and Δ6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)
Jin, Yang; Datsomor, Alex Kojo; Olsen, Rolf Erik; Vik, Jon Olav; Torgersen, Jacob Seilø; Edvardsen, Rolf Brudvik; Wargelius, Anna; Winge, Per; Grammes, Fabian (Peer reviewed; Journal article, 2020)Background With declining wild fish populations, farmed salmon has gained popularity as a source for healthy long-chain highly unsaturated fatty acids (LC-HUFA). However, the introduction of plant oil in farmed salmon ... -
The molecular basis of long chain polyunsaturated fatty acid (LC-PUFA) biosynthesis in Atlantic salmon (Salmo salar L): In vivo functions, functional redundancy and transcriptional regulation of LC-PUFA biosynthetic enzymes
Datsomor, Alex Kojo (Doctoral theses at NTNU;2019:383, Doctoral thesis, 2019)Farmed Atlantic salmon (Salmo salar L.) is a rich source of the omega-3 fatty acids (ω-3 FA), eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids, which are linked to health benefits in humans including prevention of ...