Browsing NTNU Open by Author "Dalheim, Marianne Øksnes"

Now showing items 1-8 of 8

    • Chemically modified alginates and chitosans Lateral and terminal functionalization by reductive amination 

      Dalheim, Marianne Øksnes (Doctoral theses at NTNU;2016:274, Doctoral thesis, 2016)
      ENGLISH: Polysaccharides with added functions and/or modified properties are of increasing interest in preparing new materials suitable for both industrial applications and more advanced applications within biomedical ...

    • Degradation kinetics of peptide-coupled alginates prepared via the periodate oxidation reductive amination route 

      Dalheim, Marianne Øksnes; Ulset, Ann-Sissel Teialeret; Jenssen, Ina Beate; Christensen, Bjørn E. (Journal article; Peer reviewed, 2017)
      Biomaterials based on peptide-coupled alginates must provide both optimal biological environments and tuneable stability/degradation profiles. The present work investigates the degradation pattern and kinetics of peptide-coupled ...

    • Efficient functionalization of alginate biomaterials 

      Dalheim, Marianne Øksnes; Vanacker, Julie; Najmi, Maryam A.; Aachmann, Finn Lillelund; Strand, Berit Løkensgard; Christensen, Bjørn E. (Journal article; Peer reviewed, 2016)
      Peptide coupled alginates obtained by chemical functionalization of alginates are commonly used as scaffold materials for cells in regenerative medicine and tissue engineering. We here present an alternative to the commonly ...

    • Efficient Grafting of Cyclodextrin to Alginate and Performance of the Hydrogel for Release of Model Drug 

      Omtvedt, Line Aanerud; Dalheim, Marianne Øksnes; Nielsen, Thorbjørn T.; Larsen, Kim; Strand, Berit Løkensgard; Aachmann, Finn Lillelund (Journal article; Peer reviewed, 2019)
      Controlling the rate of release of molecules from a hydrogel is of high interest for various drug delivery systems and medical devices. A strategy to alter the release profiles of soluble and poorly soluble active ingredients ...

    • Influence of amino acids, buffers, and pH on the γ-irradiation-induced degradation of alginates 

      Ulset, Ann-Sissel Teialeret; Mori, Hideki; Dalheim, Marianne Øksnes; Hara, Masayuki; Christensen, Bjørn E. (Journal article; Peer reviewed, 2014)
      Alginate-based biomaterials and medical devices are commonly subjected to γ-irradiation as a means of sterilization, either in the dry state or the gel (hydrated) state. In this process the alginate chains degrade randomly ...

    • Mechanical Properties of Ca-Saturated Hydrogels with Functionalized Alginate 

      Dalheim, Marianne Øksnes; Omtvedt, Line Aanerud; Bjørge, Isabel M.; Akbarzadeh, Anita; Mano, Joao F.; Aachmann, Finn Lillelund; Strand, Berit Løkensgard (Journal article; Peer reviewed, 2019)
      In this work, the mechanical properties and stability of alginate hydrogels containing functionalized alginates (peptide and β-cyclodextrin) were studied. There is an increasing interest in the modification of alginates ...

    • Periodate oxidation and macromolecular compaction of hyaluronan 

      Kristiansen, Kåre Andre; Dalheim, Marianne Øksnes; Christensen, Bjørn E. (Journal article; Peer reviewed, 2013)
      Partial periodate oxidation of hyaluronan leads to ring opening of the 4-linked D-glucuronate (GlcA) residues, providing a particularly flexible element within otherwise semi-flexible chains. This leads to compaction of ...

    • Single-Molecule Pair Studies of RGD-Coupled Alginate and Integrin 

      Lee, Hye Won (Master thesis, 2014)