Browsing NTNU Open by Author "Coron, Abba Elizabeth"
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Alginate Beads for the Treatment of Diabetes - Development of Larger Beads with Various Compartments
Kjesbu, Joachim Sebastian (Master thesis, 2016)Some diseases lead to the loss of specific types of cells and their associated products, notably type 1 diabetes, an autoimmune disease which causes the loss of the insulin producing β-cells native to the pancreas. Cell ... -
Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation
Ørning, Mathias Pontus; Hoem, Kine Samseth; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund; Mollnes, Tom Eirik; Brekke, Ole Lars; Espevik, Terje; Rokstad, Anne Mari (Journal article; Peer reviewed, 2016)The inflammatory potential of 12 types of alginate-based microspheres was assessed in a human whole blood model. The inflammatory potential could be categorized from low to high based on the four main alginate microsphere ... -
Current and Future Perspectives on Alginate Encapsulated Pancreatic Islet
Strand, Berit Løkensgard; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund (Journal article; Peer reviewed, 2017)Transplantation of pancreatic islets in immune protective capsules holds the promise as a functional cure for type 1 diabetes, also about 40 years after the first proof of principal study. The concept is simple in using ... -
Gel Beads of Alginate from Laminaria Hyperborea Leaf - Stability related to size and polymer distribution
Coron, Abba Elizabeth (Master thesis, 2015)Alginate microbeads have through many years of research shown great potential as an immunoisolation system for the entrapment of insulin-producing cells. However, one of the main challenges in the use of alginate gels as ... -
Strategies for Stabilising Gel Beads of Alginate from Laminaria Hyperborea Leaf by using Strontium as Gelling Ion
Bakken, Helene (Master thesis, 2018)Alginate microbeads have shown great promise as immunoisolating material for the encapsulation of living cells, such as insulin-producing cells for the treatment of diabetes. However, one of the main challenges related to ...