Blar i NTNU Open på forfatter "Christiansen, Sverre Christian"
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The Artificial Pancreas: Two Alternative Approaches to Achieve a Fully Closed Loop System with Optimal Glucose Control
Åm, Marte Kierulf; Teigen, Ingrid Anna; Riaz, Misbah; Fougner, Anders Lyngvi; Christiansen, Sverre Christian; Carlsen, Sven Magnus (Peer reviewed; Journal article, 2023)Introduction Diabetes mellitus type 1 is a chronic disease that implies mandatory external insulin delivery. The patients must monitor their blood glucose levels and administer appropriate insulin boluses to keep their ... -
The Bihormonal Artificial Pancreas: New Perspectives on the Pharmacokinetics and Pharmacodynamics of Glucagon
Teigen, Ingrid Anna (Doctoral theses at NTNU;2023:106, Doctoral thesis, 2023)Diabetes mellitus type 1 is an autoimmune disease that causes selective destruction of the insulin-producing β-cells in the pancreatic islet of Langerhans. Insulin induces glucose storage and reduces blood glucose ... -
Does AMH Reflect Follicle Number Similarly in Women with and without PCOS?
Christiansen, Sverre Christian; Eilertsen, Tina Bjørsvik; Vanky, Eszter; Carlsen, Sven Magnus (Journal article; Peer reviewed, 2016-01-22)Context: Increased Anti-Mullerian Hormone in polycystic ovary syndrome, may be due to overactive follicles rather than reflect antral follicle count. Objective: Does Anti-Mullerian Hormone reflect antral follicle ... -
The effect of glucagon on local subcutaneous blood flow in non-diabetic volunteers; a proof-of-concept study
Åm, Marte Kierulf; Munkerud, Erlend Yttersian; Berge, Mathilde Hallem; Christiansen, Sverre Christian; Carlsen, Sven Magnus (Peer reviewed; Journal article, 2022)Introduction Glucagon and insulin are the two most important hormones for glucose metabolism and have been incorporated in the dual-hormonal artificial pancreas, a device for automated glucose regulation for people with ... -
Factors influencing on subcutaneous blood circulation
Rindal, Åshild (Master thesis, 2022)Diabetes mellitus er en metabolsk sykdom der sekresjonen eller effekten av insulin er forstyrret. Denne sykdommen har blitt et verdensomspennende helseproblem, og prevalensen av diabetes blant voksne globalt har gått fra ... -
Impact of thyrotropin receptor antibody levels on fetal development in two successive pregnancies in a woman with Graves' Disease
Bjørgaas, Marit Ragnhild Rokne; Farstad, Hanne; Christiansen, Sverre Christian; Blaas, Harm-Gerd Karl (Peer reviewed; Journal article, 2013)Background: Treatment with radioiodine for Graves’ disease regularly increases the level of antithyroid antibodies, and transplacental passage of stimulating thyrotropin receptor antibodies (TRAb) may cause fetal ... -
Intraperitoneal insulin administration - superior choice for an artificial pancreas?
Dirnena-Fusini, Ilze (Doctoral theses at NTNU;2021:334, Doctoral thesis, 2021)The main focus of this thesis is to explore the intraperitoneal (IP) cavity as the location for insulin administration. We hypothesized that IP insulin administration is more physiologic as it mimics endogenous insulin ... -
Intraperitoneal insulin administration in pigs: Effect on circulating insulin and glucose levels
Dirnena-Fusini, Ilze; Åm, Marte Kierulf; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2021)Introduction The effect of intraperitoneal insulin infusion has limited evidence in the literature. Therefore, the aim of the study was to investigate the pharmacokinetics and pharmacodynamics of different intraperitoneal ... -
Performance of intermittently scanned continuous glucose monitoring systems in people with type 1 diabetes: A pooled analysis
Moser, Othmar; Sternad, Christoph; Eckstein, Max L; Szadkowska, Agnieszka; Michalak, Arkadiusz; Mader, Julia K; Ziko, Haris; Elsayed, Hesham; Aberer, Felix; Sola-Gazagnes, Agnes; Larger, Etienne; Fadini, Gian Paolo; Bonora, Benedetta Maria; Bruttomesso, Daniela; Boscari, Federico; Freckmann, Guido; Pleus, Stefan; Christiansen, Sverre Christian; Sourij, Harald (Peer reviewed; Journal article, 2021)Aims: To conduct a pooled analysis to assess the performance of intermittently scanned continuous glucose monitoring (isCGM) in association with the rate of change in sensor glucose in a cohort of children, adolescents, ... -
Pharmacokinetics of Intraperitoneally Delivered Glucagon in Pigs: A Hypothesis of First Pass Metabolism
Teigen, Ingrid Anna; Åm, Marte Kierulf; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2021)Background and Objective Artificial pancreases administering low-dose glucagon in addition to insulin have the scope to improve glucose control in patients with diabetes mellitus type 1. If such a device were to deliver ... -
Physiological effects of intraperitoneal versus subcutaneous insulin infusion in patients with diabetes mellitus type 1: A systematic review and meta-analysis
Dirnena-Fusini, Ilze; Åm, Marte Kierulf; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2021)The intraperitoneal route of administration accounts for less than 1% of insulin treatment regimes in patients with diabetes mellitus type 1 (DM1). Despite being used for decades, a systematic review of various physiological ... -
Severe bradycardia and hypotension in anaesthetized pigs: Possible interaction between octreotide, xylazine, and atropine: A case series
Åm, Marte Kierulf; Teigen, Ingrid Anna; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2023)Pigs are common animal models in diabetes research. Streptozotocin-induced destruction of pancreatic β-cells is used to induce diabetes in conscious pigs. However, in short-term non-recovery experiments, suppression of ... -
The Artificial Pancreas: A Dynamic Challenge
Stavdahl, Øyvind; Fougner, Anders Lyngvi; Kölle, Konstanze; Christiansen, Sverre Christian; Ellingsen, Reinold; Carlsen, Sven Magnus (Journal article; Peer reviewed, 2016)In patients with diabetes mellitus type 1, the pancreatic insulin production ceases, causing raise in blood glucose level (BGL) and potentially severe long-term complications. The “holy grail” of diabetes treatment is the ... -
The effect of subcutaneously injected glucagon on local blood flow
Munkerud, Erlend Yttersian; Berge, Mathilde Hallem (Master thesis, 2021)Bakgrunn Optimal glukosekontroll reduserer langtidskomplikasjonene for diabetes. Den sakte absorbsjonen og den forsinkede effekten av eksogent tilført insulin sammenlignet med den fysiologiske insulinresponsen er et stort ... -
The effect of subcutaneously injected glucagon on local bloow flow
Munkerud, Erlend Yttersian; Berge, Mathilde Hallem (Master thesis, 2021)Bakgrunn Optimal glukosekontroll reduserer langtidskomplikasjonene for diabetes. Den sakte absorbsjonen og den forsinkede effekten av eksogent tilført insulin sammenlignet med den fysiologiske insulinresponsen er et stort ... -
Vasodilatory effects of glucagon: A possible new approach to enhanced subcutaneous insulin absorption in artificial pancreas devices
Teigen, Ingrid Anna; Riaz, Misbah; Åm, Marte Kierulf; Christiansen, Sverre Christian; Carlsen, Sven Magnus (Peer reviewed; Journal article, 2022)Patients with diabetes mellitus type 1 depend on exogenous insulin to keep their blood glucose concentrations within the desired range. Subcutaneous bihormonal artificial pancreas devices that can measure glucose concentrations ...