Blar i NTNU Open på forfatter "Chen, Yue"
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Adiposity and asthma in adults: a bidirectional Mendelian randomization analysis of the HUNT Study
Sun, Yi-Qian; Brumpton, Ben Michael; Langhammer, Arnulf; Chen, Yue; Kvaløy, Kirsti; Mai, Xiao-Mei (Journal article; Peer reviewed, 2019)Background We aimed to investigate the potential causal associations of adiposity with asthma overall, asthma by atopic status or by levels of symptom control in a large adult population and stratified by sex. We also ... -
Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT Study
Sun, Yi-Qian; Richmond, Rebecca C.; Suderman, Matthew; Min, Josine L; Battram, Thomas; Flatberg, Arnar; Beisvag, Vidar; Nøst, Therese Haugdahl; Guida, Florence; Jiang, Lin; Wahl, Sissel Gyrid Freim; Langhammer, Arnulf; Skorpen, Frank; Walker, Rosie M; Bretherick, Andrew D; Zeng, Yanni; Chen, Yue; Johansson, Mattias; Sandanger, Torkjel M; Relton, Caroline L; Mai, Xiao-Mei (Peer reviewed; Journal article, 2021)Background: It is unclear if smoking-related DNA methylation represents a causal pathway between smoking and risk of lung cancer. We sought to identify novel smoking-related DNA methylation sites in blood, with repeated ... -
Associations of serum 25-hydroxyvitamin D level with incidence of lung cancer and histologic types in Norwegian adults: a case-cohort analysis of the HUNT study
Sun, Yi-Qian; Langhammer, Arnulf; Wu, Chunsen; Skorpen, Frank; Chen, Yue; Nilsen, Tom Ivar Lund; Romundstad, Pål Richard; Mai, Xiao-Mei (Journal article, 2017)Background: Previous prospective studies have shown inconsistent associations between serum 25-hydroxyvitamin D [25(OH)D] level and lung cancer incidence. The aim of the present study was to explore the associations of ... -
Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses
Sun, Yi-Qian; Burgess, Stephen; Staley, James R.; Wood, Angela M.; Bell, Steven; Kaptoge, Stephen; Guo, Qi; Bolton, Thomas R.; Mason, Amy M; Butterworth, Adam S.; Di Angelantonio, Emanuele; Vie, Gunnhild Åberge; Bjørngaard, Johan Håkon; Kinge, Jonas Minet; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2019)Objective To investigate the shape of the causal relation between body mass index (BMI) and mortality. Design Linear and non-linear mendelian randomisation analyses. Setting Nord-Trøndelag Health (HUNT) Study (Norway) ... -
Body mass index and incidence of lung cancer in the HUNT study: using observational and Mendelian randomization approaches
Jiang, Lin; Sun, Yi-Qian; Brumpton, Ben Michael; Langhammer, Arnulf; Chen, Yue; Mai, Xiao-Mei (Peer reviewed; Journal article, 2022)Background Traditional observational studies have shown an inverse association between body mass index (BMI) and lung cancer risk. Mendelian randomization (MR) analysis using genetic variants as instruments for BMI may ... -
Cod liver oil intake and incidence of asthma in Norwegian adults-the HUNT study
Mai, Xiao-Mei; Langhammer, Arnulf; Chen, Yue; Camargo, Carlos Arthuro (Journal article; Peer reviewed, 2013)Background Cod liver oil is an important source of vitamin D, but also contains other fat-soluble components such as vitamin A. Before 1999, the cod liver oil formula in Norway contained a high concentration of vitamin A ... -
Comparison of pre‐ and post‐bronchodilator lung function as predictors of mortality: The HUNT Study
Bhatta, Laxmi; Leivseth, Linda; Carslake, David; Langhammer, Arnulf; Mai, Xiao-Mei; Chen, Yue; Henriksen, Anne Hildur; Brumpton, Ben Michael (Peer reviewed; Journal article, 2019)Background and objective Post‐bronchodilator (BD) lung function is recommended for the diagnosis of chronic obstructive pulmonary disease (COPD). However, often only pre‐BD lung function is used in clinical practice or ... -
Cross-Sectional and Prospective Cohort Study of Serum 25-Hydroxyvitamin D Level and Obesity in Adults
Mai, Xiao-Mei; Chen, Yue; Camargo, Carlos Arthuro; Langhammer, Arnulf (Journal article; Peer reviewed, 2012)Experimental studies suggest that vitamin D modulates the activity of adipocytes. The authors examined baseline serum 25-hydroxyvitamin D (25(OH)D) level in relation to prevalent and cumulative incident obesity in Norway. ... -
Determinants of vitamin D supplement use in Canadians
McCormack, Daniel; Mai, Xiao-Mei; Chen, Yue (Journal article; Peer reviewed, 2015)To determine the prevalence of vitamin D supplement use in Canadian adults and associations with demographic and socio-economic variables. Data from the Healthy Aging module of the Canadian Community Health Survey were ... -
Factors associated with vitamin D deficiency in a Norwegian population: the HUNT Study
Larose, Tricia L; Chen, Yue; Camargo, Carlos Arthuro; Langhammer, Arnulf; Romundstad, Pål Richard; Mai, Xiao-Mei (Journal article; Peer reviewed, 2014)Vitamin D deficiency occurs worldwide. Winter season and high Body Mass Index (BMI) are associated with low levels of serum 25-hydroxyvitamin D (25(OH)D). We estimated the prevalence of vitamin D deficiency in a Norwegian ... -
General and abdominal obesity and incident asthma in adults: the HUNT study
Brumpton, Ben Michael; Langhammer, Arnulf; Romundstad, Pål Richard; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2013)Measures of body mass index (BMI) and waist circumference define general obesity and abdominal obesity respectively. While high BMI has been established as a risk factor for asthma in adults, waist circumference has seldom ... -
GOLD Classifications, COPD Hospitalization, and All-Cause Mortality in Chronic Obstructive Pulmonary Disease: The HUNT Study
Bhatta, Laxmi; Leivseth, Linda; Mai, Xiao-Mei; Henriksen, Anne Hildur; Carslake, David; Chen, Yue; Langhammer, Arnulf; Brumpton, Ben Michael (Peer reviewed; Journal article, 2020)Purpose: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published three classifications of COPD from 2007 to 2017. No studies have investigated the ability of these classifications to predict ... -
Intake of multivitamin supplements and incident asthma in Norwegian adults: the HUNT study
Jiang, Lin; Brumpton, Ben Michael; Langhammer, Arnulf; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2015)Although intake of multivitamin supplements is becoming increasingly popular, the relationship between intake of multivitamin supplements and incident asthma remains unclear. Prospective studies in adults with long-term ... -
Metabolic syndrome and incidence of asthma in adults: the HUNT study
Brumpton, Ben Michael; Camargo, Carlos; Romundstad, Pål Richard; Langhammer, Arnulf; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2013)Obesity is a risk factor for incident asthma in adults, and obesity is a major component of metabolic syndrome. This study aimed to explore the associations of metabolic syndrome and its components with the cumulative ... -
Mixed evidence for the relationship between periodontitis and Alzheimer’s disease: A bidirectional Mendelian randomization study
Sun, Yi-Qian; Richmond, Rebecca C.; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2020)Recent experimental studies indicated that a periodontitis-causing bacterium might be a causal factor for Alzheimer’s disease (AD). We applied a two-sample Mendelian randomization (MR) approach to examine the potential ... -
Physical Activity and Incident Asthma in Adults: The HUNT Study, Norway.
Brumpton, Ben Michael; Langhammer, Arnulf; Ferreira, Manuel A R; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2016)Objective: We aimed to investigate the associations of physical activity and change in physical activity with incident asthma in a cohort of Norwegian adults. Design: We conducted a prospective cohort study using ... -
Potential causal associations of serum 25-hydroxyvitamin D with lipids: a Mendelian randomization approach of the HUNT study
Mai, Xiao-Mei; Videm, Vibeke; Sheehan, Nuala A.; Chen, Yue; Langhammer, Arnulf; Sun, Yi-Qian (Journal article; Peer reviewed, 2018)Background: Observational studies have shown consistent associations between higher circulating 25-hydroxyvitamin D [25(OH)D] levels and favorable serum lipids. We sought to investigate if such associations were causal. ... -
Prolonged Sitting, Its Combination With Physical Inactivity and Incidence of Lung Cancer: Prospective Data From the HUNT Study
Jiang, Lin; Sun, Yi-Qian; Brumpton, Ben Michael; Langhammer, Arnulf; Chen, Yue; Nilsen, Tom Ivar Lund; Mai, Xiao-Mei (Journal article; Peer reviewed, 2019)Background: Prolonged sitting as a major sedentary behavior potentially contributes to illness, but its relation with lung cancer risk is unclear. Prolonged sitting can be presented in physically active or inactive ... -
Reproductive factors in relation to incidence of lung and colorectal cancers in a Norwegian women cohort: the HUNT Study
Denos, Marion; Sun, Yi-Qian; Brumpton, Ben Michael; Langhammer, Arnulf; Chen, Yue; Mai, Xiao-Mei (Peer reviewed; Journal article, 2022)Context: The roles of reproductive factors in the etiology of lung and colorectal cancers, among the most common cancers in women, are unclear. Objective: We aimed to explore whether female reproductive factors were ... -
Serum 25-hydroxyvitamin D level in relation to weight change and the risk of weight gain in adults of normal weight at baseline: the Norwegian HUNT cohort study
Heitz, Adaline; Mai, Xiao-Mei; Chen, Yue; Sun, Yi-Qian (Peer reviewed; Journal article, 2020)Objective We sought to investigate the relationship of serum 25-hydroxyvitamin D (25(OH)D) level with weight change and the risk of weight gain in an adult population who had normal weight at baseline and were followed up ...