• Ancient and modern genomes unravel the evolutionary history of the rhinoceros family 

      Liu, Shanlin; Westbury, Michael V; Dussex, Nicolas; Mitchell, Kieren J.; Sinding, Mikkel-Holger S.; Heintzman, Peter D.; Duchêne, David A.; Kapp, Joshua D.; von Seth, Johanna; Heiniger, Holly; Sánchez-Barreiro, Fatima; Margaryan, Ashot; André-Olsen, Remi; De Cahsan, Binia; Meng, Guanliang; Yang, Chentao; Chen, Lei; van der Valk, Tom; Moodley, Yoshan; Rookmaaker, Kees; Bruford, Michael W.; Ryder, Oliver; Steiner, Cynthia; Bruins-van Sonsbeek, Linda G. R.; Vartanyan, Sergey; Guo, Chunxue; Cooper, Alan; Kosintsev, Pavel; Kirillova, Irina V.; Lister, Adrian M.; Marques-Bonet, Tomas; Gopalakrishnan, Shyam; Dunn, Robert R.; Lorenzen, Eline D.; Shapiro, Beth; Zhang, Guojie; Antoine, Pierre-Olivier; Dalén, Love; Gilbert, Marcus Thomas Pius (Peer reviewed; Journal article, 2021)
      Only five species of the once-diverse Rhinocerotidae remain, making the reconstruction of their evolutionary history a challenge to biologists since Darwin. We sequenced genomes from five rhinoceros species (three extinct ...
    • The Earth BioGenome Project 2020: Starting the clock 

      Lewin, Harris A.; Richards, Stephen; Aiden, Erez Lieberman; Allende, Miguel L.; Archibald, John M.; Bálint, Miklós; Barker, Katharine B.; Baumgartner, Bridget; Belov, Katherine; Bertorelle, Giorgio; Blaxter, Mark L.; Cai, Jing; Caperello, Nicolette D.; Carlson, Keith; Castilla-Rubio, Juan Carlos; Chaw, Shu-Miaw; Chen, Lei; Childers, Anna K.; Coddington, Jonathan A.; Conde, Dalia A.; Corominas, Montserrat; Crandall, Keith A.; Crawford, Andrew J.; DiPalma, Federica; Durbin, Richard; Ebenezer, ThankGod E.; Edwards, Scott V.; Fedrigo, Olivier; Flicek, Paul; Formenti, Giulio; Gibbs, Richard A.; Gilbert, Marcus Thomas Pius; Goldstein, Melissa M.; Graves, Jennifer Marshall; Greely, Henry T.; Grigoriev, Igor V.; Hackett, Kevin J.; Hall, Neil; Haussler, David; Helgen, Kristofer M.; Hogg, Carolyn J.; Isobe, Sachiko; Jakobsen, Kjetill Sigurd; Janke, Axel; Jarvis, Erich D.; Johnson, Warren E.; Jones, Steven J.M.; Karlsson, Elinor K.; Kersey, Paul J.; Kim, Jin-Hyoung; Kress, W. John; Kuraku, Shigehiro; Lawniczak, Mara K.N.; Leebens-Mack, James H.; Li, Xueyan; Lindblad-Toh, Kerstin; Liu, Xin; Lopez, Jose V.; Marques-Bonet, Tomas; Mazard, Sophie; Mazet, Jonna A.K.; Mazzoni, Camila J.; Myers, Eugene W.; O’Neill, Rachel J.; Paez, Sadye; Park, Hyun; Robinson, Gene E.; Roquet, Cristina; Ryder, Oliver A.; Sabir, Jamal S.M.; Shaffer, H. Bradley; Shank, Timothy M.; Sherkow, Jacob S.; Soltis, Pamela S.; Tang, Boping; Tedersoo, Leho; Uliano-Silva, Marcela; Wang, Kun; Wei, Xiaofeng; Wetzer, Regina; Wilson, Julia L.; Xu, Xun; Yang, Huanming; Yoder, Anne D.; Zhang, Guojie (Peer reviewed; Journal article, 2022)
    • Methotrexate attenuates vascular inflammation through an adenosine- microRNA-dependent pathway 

      Yang, Dafeng; Haemmig, Stefan; Zhou, Haoyang; Pérez-Cremades, Daniel; Sun, Xinghui; Chen, Lei; Li, Jie; Haneo-Mejia, Jorge; Yang, Tianlun; Hollan, Ivana; Feinberg, Mark W. (Peer reviewed; Journal article, 2021)
      Endothelial cell (EC) activation is an early hallmark in the pathogenesis of chronic vascular diseases. MicroRNA-181b (Mir181b) is an important anti-inflammatory mediator in the vascular endothelium affecting endotoxemia, ...
    • A towering genome: Experimentally validated adaptations to high blood pressure and extreme stature in the giraffe 

      Liu, Chang; Gao, Jianbo; Cui, Xinxin; Li, Zhipeng; Chen, Lei; Yuan, Yuan; Zhang, Yaolei; Mei, Liangwei; Zhao, Lan; Cai, Dan; Hu, Mingliang; Zhou, Botong; Li, Zihe; Qin, Tao; Si, Huazhe; Li, Guangyu; Lin, Zeshan; Xu, Yicheng; Zhu, Chenglong; Yin, Yuan; Zhang, Chenzhou; Xu, Wenjie; Li, Qingjie; Wang, Kun; Gilbert, Marcus Thomas Pius; Heller, Rasmus; Wang, Wen; Huang, Jinghui; Qiu, Qiang (Peer reviewed; Journal article, 2021)
      The suite of adaptations associated with the extreme stature of the giraffe has long interested biologists and physiologists. By generating a high-quality chromosome-level giraffe genome and a comprehensive comparison with ...