Browsing NTNU Open by Author "Carstam, Louise"
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Disulfiram repurposing combined with nutritional copper supplement as add-on to chemotherapy in recurrent glioblastoma (DIRECT): Study protocol for a randomized controlled trial
Jakola, Asgeir S.; Werlenius, Katja; Mudaisi, Munila; Hylin, Sofia; Kinhult, Sara; bartek, Jiri Jr.; Salvesen, Øyvind; Carlsen, Sven Magnus; Strandeus, Michael; Lindskog, Magnus; Lofgren, David; Rydenhaug, Bertil; Carstam, Louise; Gulati, Sasha; Solheim, Ole; Bartek, Jiri; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2018)Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to treat alcoholism since the 1950s. There is now independent preclinical data that supports DSF as an anticancer agent, and ... -
Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study
Rydén, Isabelle; Thurin, Erik; Carstam, Louise; Smits, Anja; Gulati, Sasha; Henriksson, Roger; Salvesen, Øyvind; Jakola, Asgeir Store (Journal article; Peer reviewed, 2021)Background: Low-grade glioma (LGG) is a relatively rare type of brain tumour. The use of antidepressant, sedative and anti-epileptic drugs can reflect the burden of the disease. While epilepsy is well-described in patients ... -
Socioeconomic factors affect treatment delivery for patients with low grade glioma: a Swedish population-based study
Carstam, Louise; Rydén, Isabelle; Gulati, Sasha; Rydenhag, Bertil; Henriksson, Roger; Salvesen, Øyvind; Smits, Anja; Jakola, Asgeir S (Peer reviewed; Journal article, 2019)Background Despite aspirations to achieve equality in healthcare we know that socioeconomic differences exist and may affect treatment and patient outcome, also in serious diseases such as cancer. We investigated ...