Browsing NTNU Open by Author "Bush, Nigel"

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Acoustic Cluster Therapy (ACT) - pre-clinical proof of principle for local drug delivery and enhanced uptake.

van Wamel, Annemieke; Healey, Andrew; Sontum, Per C.; Kvåle, Svein; Bush, Nigel; Bamber, Jeffrey; Davies, Ruth Catharina de Lange (Journal article; Peer reviewed, 2016)

Proof of principle for local drug delivery with Acoustic Cluster Therapy (ACT) was demonstrated in a human prostate adenocarcinoma growing in athymic mice, using near infrared (NIR) dyes as model molecules. A dispersion ...
Acoustic Cluster Therapy (ACT) enhances the therapeutic efficacy of paclitaxel and Abraxane® for treatment of human prostate adenocarcinoma in mice

van Wamel, Annemieke; Sontum, Per C.; Healey, Andrew; Kvåle, Svein; Bush, Nigel; Bamber, Jeffrey; Davies, Ruth Catharina de Lange (Journal article; Peer reviewed, 2016)

Acoustic cluster therapy (ACT) is a novel approach for ultrasound mediated, targeted drug delivery. In the current study, we have investigated ACT in combination with paclitaxel and Abraxane® for treatment of a subcutaneous ...