• Efficacy, tolerability and pharmacokinetic variability of brivaracetam in adults with difficult-to-treat epilepsy 

      Svendsen, Torleiv; Brodtkorb, Eylert; Linge, Hanna Lande; Burns, Margrete Larsen; Johannessen, Svein Ivar; Nakken, Karl Otto; Lossius, Morten Ingvar; Landmark, Cecilie Johannessen (Peer reviewed; Journal article, 2022)
      Purpose: Brivaracetam (BRV) is one of our latest antiseizure medications (ASMs). It is an analogue of levetiracetam with limited real-life experience. The purpose of this study was to evaluate clinical experience with BRV ...
    • Felles referanseområder for antiepileptika 

      Reimers, Arne; Berg, Jon Andsnes; Burns, Margrete Larsen; Landmark, Cecilie Johannessen (Journal article; Peer reviewed, 2017)
      Antiepileptika er grunnsteinen i behandlingen av epilepsi og brukes også ved en rekke andre indikasjoner. Serumkonsentrasjonsmåling av antiepileptika har hatt lang tradisjon som hjelpemiddel i behandling av epilepsi i ...
    • Pharmacokinetic data on brivaracetam, lacosamide and Perampanel during pregnancy and lactation 

      Landmark, Cecilie Johannessen; Rektorlie, Lene; Burns, Margrete Larsen; Revdal, Eline; Johannessen, Svein Ivar; Brodtkorb, Eylert (Peer reviewed; Journal article, 2021)
      We present pharmacokinetic data during pregnancy and lactation for brivaracetam, lacosamide and perampanel based on two case studies. Patient 1 used brivaracetam as monotherapy and gave birth to twins. Patient 2 used a ...
    • Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines 

      Reimers, Arne; Berg, Jon Andsnes; Burns, Margrete Larsen; Brodtkorb, Eylert; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Journal article; Peer reviewed, 2018)
      Background and objective: Laboratories sometimes use different reference ranges for the same antiepileptic drug (AED), particularly for new and poorly investigated drugs. This may contribute to misunderstandings, concerns ...
    • The Impact of Pharmacokinetic Interactions with Eslicarbazepine Acetate Versus Oxcarbazepine and Carbamazepine in Clinical Practice 

      Landmark, Cecilie Johannessen; Svendsen, Torleiv; Dinarevic, Jasmin; Kufaas, Ruben F.; Reimers, Arne; Brodtkorb, Eylert; Baftiu, Arton; Burns, Margrete Larsen; Johannessen, Svein Ivar (Journal article; Peer reviewed, 2016)
      Background: Eslicarbazepine acetate (ESL) is a new anti-epileptic drug (AED) chemically related to oxcarbazepine (OXC) and carbamazepine (CBZ) and is increasingly used in clinical practice. The purpose of the study was to ...
    • Therapeutic Drug Monitoring of Lacosamide in Norway: Focus on Pharmacokinetic Variability, Efficacy and Tolerability. 

      Svendsen, Torleiv; Brodtkorb, Eylert; Baftiu, Arton; Burns, Margrete Larsen; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Journal article; Peer reviewed, 2017)
      Lacosamide (LCM) is a new antiepileptic drug (AED). Experience from therapeutic drug monitoring (TDM) in clinical practice is limited. The purpose of this study is to evaluate the pharmacokinetic variability of LCM in ...