Browsing NTNU Open by Author "Brækhus, Anne"

Now showing items 1-11 of 11

    • Cohort profile: the Norwegian Registry of Persons Assessed for Cognitive Symptoms (NorCog) - a national research and quality registry with a biomaterial collection 

      Medbøen, Ingrid Tøndel; Persson, Karin Ester Torun; Nåvik, Marit; Totland, Torunn Holm; Bergh, Sverre; Treviño, Cathrine Selnes; Ulstein, Ingun; Engedal, Knut; Knapskog, Anne Brita; Brækhus, Anne; Øksengård, Anne Rita; Horndalsveen, Peter Otto; Saltvedt, Ingvild; Lyngroth, Anne Liv; Ranhoff, Anette Hylen; Skrettingland, Dagny B; Naik, Mala; Soares, Jelena Zugic; Johnsen, Bente; Selbæk, Geir (Peer reviewed; Journal article, 2022)
      Purpose The Norwegian Registry of Persons Assessed for Cognitive Symptoms (NorCog) was established to harmonise and improve the quality of diagnostic practice across clinics assessing persons with cognitive symptoms in ...

    • Cortisol levels among older people with and without depression and dementia 

      Barca, Maria Lage; Eldholm, Rannveig Sakshaug; Persson, Karin Ester Torun; Björklöf, Guro Hanevold; Borza, Tom; Telenius, Elisabeth Wiken; Knapskog, Anne-Brita; Brækhus, Anne; Saltvedt, Ingvild; Selbæk, Geir; Engedal, Knut (Journal article; Peer reviewed, 2018)
      Cortisol dysregulation has been reported in dementia and depression. Cortisol levels and its associates were investigated among older people living at home and in nursing homes, in a cross-sectional study. A sample of 650 ...

    • Current and Future Prevalence Estimates of Mild Cognitive Impairment, Dementia, and Its Subtypes in a Population-Based Sample of People 70 Years and Older in Norway: The HUNT Study 

      Gjøra, Linda; Strand, Bjørn Heine; Bergh, Sverre; Borza, Tom; Brækhus, Anne; Engedal, Knut Arne; Johannessen, Aud; Kvello-Alme, Marte; Krokstad, Steinar; Livingston, Gill; Matthews, Fiona E; Myrstad, Christian; Skjellegrind, Håvard; Thingstad, Pernille; Aakhus, Eivind; Aam, Stina; Selbæk, Geir (Peer reviewed; Journal article, 2021)
      Background: Having accurate, up-to-date information on the epidemiology of mild cognitive impairment (MCI) and dementia is imperative. Objective: To determine the prevalence of MCI and dementia in Norway using data ...

    • Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease 

      Creese, Byron; Vassos, Evangelos; Bergh, Sverre; Athanasiu, Lavinia; Johar, Iskandar; Rongve, Arvid; Medbøen, Ingrid Tøndel; Da Silva, Miguel Vasconcelos; Aakhus, Eivind; Andersen, Fred; Bettella, Francesco; Brækhus, Anne; Djurovic, Srdjan; Paroni, Giulia; Proitsi, Petroula; Saltvedt, Ingvild; Seripa, Davide; Stordal, Eystein; Fladby, Tormod; Aarsland, Dag; Andreassen, Ole Andreas; Ballard, Clive; Selbæk, Geir (Journal article; Peer reviewed, 2019)
      Psychosis (delusions or hallucinations) in Alzheimer’s disease (AD + P) occurs in up to 50% of individuals and is associated with significantly worse clinical outcomes. Atypical antipsychotics, first developed for ...

    • Factors that influence the levels of cerebrospinal fluid biomarkers in memory clinic patients 

      Knapskog, Anne Brita; Eldholm, Rannveig Sakshaug; Brækhus, Anne; Engedal, Knut; Saltvedt, Ingvild (Journal article; Peer reviewed, 2017)
      Background The cerebrospinal fluid (CSF) biomarkers amyloid β (Aβ), phospho tau (P-tau) and total tau (T-tau) are used increasingly to support a clinical diagnosis of Alzheimer’s disease. The diagnostic power of these ...

    • Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk 

      Jansen, Iris E.; Savage, Jeanne E.; Watanabe, Kyoko; Bryois, Julien; Williams, Dylan M.; Steinberg, Stacy; Sealock, Julia; Karlsson, Ida K.; Hägg, Sara; Athanasiu, Lavinia; Voyle, Nicola; Proitsi, Petroula; Witoelar, Aree; Stringer, Sven; Aarsland, Dag; Almdahl, Ina Selseth; Andersen, Fred; Bergh, Sverre; Bettella, Francesco; Björnsson, Sigurbjörn; Brækhus, Anne; Bråthen, Geir; de Leeuw, Christiaan A.; Desikan, Rahul S.; Djurovic, Srdjan; Dumitrescu, Logan; Fladby, Tormod; Hohman, Timothy J.; Jónsson, Pálmi V.; Kiddle, Steven J; Rongve, Arvid; Saltvedt, Ingvild; Sando, Sigrid Botne; Selbæk, Geir; Shoai, Maryam; Skene, Nathan G.; Snædal, Jón G.; Stordal, Eystein; Ulstein, Ingun; Wang, Yunpeng; White, Linda Rosemary; Hardy, John; Hjerling-Leffler, Jens; Sullivan, Patrick; van der Flier, Wiesje M.; Dobson, Richard; Davis, Lea K; Stefánsson, Hreinn; Stefánsson, Kári; Pedersen, Nancy L; Ripke, Stephan; Andreassen, Ole Andreas; Posthuma, Danielle (Journal article; Peer reviewed, 2019)
      Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20 disease-associated genomic loci. Yet these only explain a small proportion of the genetic variance, indicating that undiscovered loci ...

    • Meta-analysis of Alzheimer’s disease on 9,751 samples from Norway and IGAP study identifies four risk loci 

      Witoelar, Aree; Rongve, Arvid; Almdahl, Ina Selseth; Ulstein, Ingun; Engvig, Andreas; White, Linda Rosemary; Selbæk, Geir; Stordal, Eystein; Andersen, Fredrik; Brækhus, Anne; Saltvedt, Ingvild; Engedal, Knut; Hughes, Timothy; Bergh, Sverre; Bråthen, Geir; Bogdanovic, Nenad; Bettella, Francesco; Wang, Yunpeng; Athanasiu, Lavinia; Bahrami, Shahram; Le Hellard, Stephanie; Giddaluru, Sudheer; Dale, Anders M; Sando, Sigrid Botne; Steinberg, Stacy; Stefansson, Hreinn; Snaedal, Jon; Desikan, Rahul S; Stefansson, Kari; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2018)
      A large fraction of genetic risk factors for Alzheimer’s Disease (AD) is still not identified, limiting the understanding of AD pathology and study of therapeutic targets. We conducted a genome-wide association study (GWAS) ...

    • MRI-assessed atrophy subtypes in Alzheimer’s disease and the cognitive reserve hypothesis 

      Persson, Karin; Eldholm, Rannveig Sakshaug; Barca, Maria Lage; Cavallin, Lena; Ferreira, Daniel; Knapskog, Anne Brita; Selbæk, Geir; Brækhus, Anne; Saltvedt, Ingvild; Westman, Eric; Engedal, Knut (Journal article; Peer reviewed, 2017)
      Background/Aims MRI assessment of the brain has demonstrated four different patterns of atrophy in patients with Alzheimer’s disease dementia (AD): typical AD, limbic-predominant AD, hippocampal-sparing AD, and a subtype ...

    • Progression of Alzheimer's Disease: A Longitudinal Study in Norwegian Memory Clinics 

      Eldholm, Rannveig Sakshaug; Barca, Maria Lage; Persson, Karin; Knapskog, Anne-Brita; Kersten, Hege; Engedal, Knut; Selbæk, Geir; Brækhus, Anne; Skovlund, Eva; Saltvedt, Ingvild (Journal article; Peer reviewed, 2017)
      Background: The course of Alzheimer’s disease (AD) varies considerably between individuals. There is limited evidence on factors important for disease progression. Objective: The primary aim was to study the progression ...

    • Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations 

      Motazedi, Ehsan; Cheng, Weiqiu; Thomassen, Jesper Qvist; Frei, Oleksandr; Rongve, Arvid; Athanasiu, Lavinia; Bahrami, Shahram; Shadrin, Alexey; Ulstein, Ingun; Stordal, Eystein; Brækhus, Anne; Saltvedt, Ingvild; Sando, Sigrid Botne; O'Connell, Kevin Sean; Hindley, Guy; van der Meer, Dennis; Bergh, Sverre; Nordestgaard, Børge G.; Tybjærg-Hansen, Anne; Bråthen, Geir; Philstrøm, Lasse; Djurovic, Srdjan; Frikke-Schmidt, Ruth; Fladby, Tormod; Aarsland, Dag; Selbæk, Geir; Seibert, Tyler Michael; Dale, Anders; Fan, Chun C.; Andreassen, Ole (Journal article; Peer reviewed, 2022)

    • Visual Evaluation of Medial Temporal Lobe Atrophy as a Clinical Marker of Conversion from Mild Cognitive Impairment to Dementia and for Predicting Progression in Patients with Mild Cognitive Impairment and Mild Alzheimer's Disease 

      Persson, Karin; Barca, Maria Lage; Eldholm, Rannveig Sakshaug; Cavallin, Lena; Saltyte Benth, Jurate; Selbæk, Geir; Brækhus, Anne; Saltvedt, Ingvild; Engedal, Knut (Journal article; Peer reviewed, 2017)
      Background/Aims: To evaluate whether visual assessment of medial temporal lobe atrophy (vaMTA) can predict 2-year conversion from mild cognitive impairment (MCI) to dementia and progression of MCI and Alzheimer's disease ...