Browsing NTNU Open by Author "Boyartchuk, Victor"
Now showing items 1-6 of 6
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Exploring the interplay between lipid metabolism and inflammation
Tande, Erlend Bjørkøy (Doctoral theses at NTNU;2025:42, Doctoral thesis, 2025) -
Human metapneumovirus driven IFN-β production antagonizes macrophage transcriptional induction of IL1-β in response to bacterial pathogens
Loevenich, Simon; Montaldo, Nicola Pietro; Wickenhagen, Arthur; Sherstova, Tatyana; van Loon, Barbara; Boyartchuk, Victor; Anthonsen, Marit Walbye (Journal article; Peer reviewed, 2023) -
Human Metapneumovirus Induces IRF1 via TANK-Binding Kinase 1 and Type I IFN
Loevenich, Simon; Spahn, Alix Saskia; Rian, Kristin; Boyartchuk, Victor; Anthonsen, Marit Walbye (Peer reviewed; Journal article, 2021)The innate immune and host-protective responses to viruses, such as the airway pathogen human metapneumovirus (HMPV), depend on interferons (IFNs) that is induced through TANK-binding kinase 1 (TBK1) and IFN regulatory ... -
Investigating the Role of TRIM37 and CD5L in Osteoarthritis: A Study on Chondrocyte Dysfunction
Ortega, Carolina Gómez (Master thesis, 2023)Osteoarthritis (OA) is a chronic joint disease that affects millions of people worldwide. OA represents a substantial burden, not only in terms of patient quality of life but also in healthcare costs. Despite its high ... -
Role of CD5L in control of human innate immune function
Moharrami, Neda Nejati (Doctoral theses at NTNU;2018:395, Doctoral thesis, 2018)Innate immune signaling has numerous ways to sense changes in cellular metabolism to ensure appropriate response to threatening agents. For instance, cholesterol metabolites act as ligands for nuclear receptor transcription ... -
RORα controls inflammatory state of human macrophages
Nejati Moharrami, Neda; Tande, Erlend Bjørkøy; Ryan, Liv; Espevik, Terje; Boyartchuk, Victor (Journal article; Peer reviewed, 2018)ROR family of nuclear receptor transcription factors forms nodes connecting metabolic and inflammatory signaling pathways. The RORα members of the family have intrinsic transcriptional activity and they are involved in ...