Browsing NTNU Open by Author "Bofin, Anna Mary"
Now showing items 1-11 of 11
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Androgen receptor expression in breast cancer subtypes
Kraby, Maria Ryssdal (Master thesis, 2016)Background The androgen receptor (AR) is frequently expressed in breast cancer, and associated with good prognosis in ER-positive breast cancers. Due to its high prevalence, AR is also a possible target for therapeutic ... -
Breast Cancer Awareness Among Women Employed at Dhulikhel Hospital and its Outreach Centres
Waarum, Petter; Moosmayer, Jonas Haugstad (Master thesis, 2023) -
Breast Cancer Awareness Among Women Employed at Dhulikhel Hospital and its Outreach Centres
Waarum, Petter; Moosmayer, Jonas Haugstad (Master thesis, 2023) -
Collagen patterns in breast cancer
Brabrand, Anders; Kariuki, Ian Irura (Master thesis, 2013)Background: Research on breast cancer has largely been dominated by research on the epithelial component of the tumour. However, recent studies have shed light on the role the stroma plays in both the development and ... -
Expression of Transforming growth factor beta in Breast Cancer Subtypes
Brabrand, Lotte (Master thesis, 2017)Background: Normally, transforming growth factor beta (TGF-b) functions as a tumorsuppressor. But, during carcinogenesis, malignant cells become insensitive to TGF-b´s growth inhibitory abilities, and the traits of TGF-b ... -
FastPathology: An open-source platform for deep learning-based research and decision support in digital pathology
Pedersen, André; Valla, Marit; Bofin, Anna Mary; Perez de Frutos, Javier; Reinertsen, Ingerid; Smistad, Erik (Peer reviewed; Journal article, 2021)Deep convolutional neural networks (CNNs) are the current state-of-the-art for digital analysis of histopathological images. The large size of whole-slide microscopy images (WSIs) requires advanced memory handling to read, ... -
MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes
Klæstad, Elise; Opdahl, Signe; Engstrøm, Monica J; Ytterhus, Borgny; Wik, Elisabeth; Bofin, Anna Mary; Valla, Marit (Peer reviewed; Journal article, 2020)Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 ... -
PD-L1 Protein Expression in Breast Cancer
Saastad, Sigurd August; Skjervold, Anette Hansen; Ytterhus, Borgny; Engstrøm, Monica Jernberg; Bofin, Anna Mary (Master thesis, 2023)Tumorcellers evne til å unngå destruksjon av immunforsvaret, har blitt foreslått som et av de nye kjennetegnene til kreft av Hanahan og Weinberg i 2011. Både T-celler, B-celler, makrofager, polymorfonukleære celler, naturlige ... -
PHH3 in breast cancer - Using immunohistochemistry to visualize mitoses
Hansen, Michelle (Master thesis, 2016)Mitotic activity is an independent prognostic indicator in breast cancer and is one of the three morphological characteristics assessed when determining histopathological grade. However, mitotic counts carried out on ... -
Proliferation in molecular subtypes of breast cancer
Klæstad, Elise (Doctoral theses at NTNU;2023:30, Doctoral thesis, 2023)Breast cancer is a heterogeneous disease. Using immunohistochemistry (IHC) and in situ hybridization (ISH) breast cancers can be divided into molecular subtypes with different prognosis and response to treatment. Increased ... -
Visual and digital assessment of Ki-67 in breast cancer tissue - a comparison of methods
Skjervold, Anette Hansen; Pettersen, Henrik P Sahlin; Valla, Marit; Opdahl, Signe; Bofin, Anna Mary (Peer reviewed; Journal article, 2022)Background In breast cancer (BC) Ki-67 cut-off levels, counting methods and inter- and intraobserver variation are still unresolved. To reduce inter-laboratory differences, it has been proposed that cut-off levels for ...