• Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals 

      Chan, Y; Holmen, Oddgeir; Dauber, A; Vatten, Lars Johan; Havulinna, AS; Skorpen, Frank; Kvaløy, Kirsti; Silander, K; Nguyen, Thutrang T; Willer, C; Boehnke, M; Perola, M; Palotie, A; Salomaa, V; Hveem, Kristian; Frayling, TM; Hirschhorn, JN; Weedon, MN (Journal article; Peer reviewed, 2011)
      Common genetic variants have been shown to explain a fraction of the inherited variation for many common diseases and quantitative traits, including height, a classic polygenic trait. The extent to which common variation ...