• 18F-FACBC PET/MRI in diagnostic assessment and neurosurgery of gliomas 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Hong, Yan Dai; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2019)
      Purpose This pilot study aimed to evaluate the amino acid tracer 18F-FACBC with simultaneous PET/MRI in diagnostic assessment and neurosurgery of gliomas. Materials and Methods Eleven patients with suspected primary or ...
    • 18F-FACBC PET/MRI in the evaluation of human brain metastases: a case report 

      Johannessen, Knut; Berntsen, Erik Magnus; Johansen, Håkon; Solheim, Tora S; Karlberg, Anna Maria; Eikenes, Live (Peer reviewed; Journal article, 2021)
      Abstract Background: Patients with metastatic cancer to the brain have a poor prognosis. In clinical practice, MRI is used to delineate, diagnose and plan treatment of brain metastases. However, MRI alone is limited in ...
    • Angiogenesis and radiological tumor growth in patients with glioblastoma 

      Mikkelsen, Vilde Elisabeth; Stensjøen, Anne Line; Granli, Unn Sophie; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole; Torp, Sverre Helge (Journal article; Peer reviewed, 2018)
      Background The preoperative growth of human glioblastomas (GBMs) has been shown to vary among patients. In animal studies, angiogenesis has been linked to hypoxia and faster growth of GBM, however, its relation to the ...
    • Brain infarctions after glioma surgery: prevalence, radiological characteristics and risk factors 

      Strand, Per Sveino; Berntsen, Erik Magnus; Fyllingen, Even Hovig; Sagberg, Lisa Millgård; Reinertsen, Ingerid; Gulati, Sasha; Bouget, David; Solheim, Ole (Peer reviewed; Journal article, 2021)
      Background: Prevalence, radiological characteristics, and risk factors for peritumoral infarctions after glioma surgery are not much studied. In this study, we assessed shape, volume, and prevalence of peritumoral infarctions ...
    • Diagnostic accuracy of anti-3-[18F]-FACBC PET/MRI in gliomas 

      Karlberg, Anna Maria; Pedersen, Lars Kjelsberg; Vindstad, Benedikte Emilie; Skjulsvik, Anne Jarstein; Johansen, Håkon; Solheim, Ole Skeidsvoll; Skogen, Karoline; Kvistad, Kjell Arne; Bogsrud, Trond; Myrmel, Kristin Smistad; Giskeødegård, Guro F.; Ingebrigtsen, Tor; Berntsen, Erik Magnus; Eikenes, Live (Peer reviewed; Journal article, 2023)
      Purpose - The primary aim was to evaluate whether anti-3-[18F]FACBC PET combined with conventional MRI correlated better with histomolecular diagnosis (reference standard) than MRI alone in glioma diagnostics. The ability ...
    • Diagnostic Value of 18F-FACBC PET/MRI in Brain Metastases 

      Øen, Silje Kjærnes; Johannessen, Knut; Pedersen, Lars Kjelsberg; Berntsen, Erik Magnus; Totland, Jon Andre; Johansen, Håkon; Bogsrud, Trond Velde; Solheim, Tora S; Karlberg, Anna Maria; Eikenes, Live (Peer reviewed; Journal article, 2022)
      Purpose The study aims to evaluate whether combined 18F-FACBC PET/MRI could provide additional diagnostic information compared with MRI alone in brain metastases. Patients and Methods Eighteen patients with newly ...
    • Express Team-Based Learning (eTBL): A Time-Efficient TBL Approach in Neuroradiology 

      Smeby, Susanne Skjervold; Lillebo, Børge; Slørdahl, Tobias Schmidt; Berntsen, Erik Magnus (Peer reviewed; Journal article, 2019)
      Rationale and Objectives Team-based learning (TBL) is a student-centred, teacher-directed instructional method that promotes active learning. The application phase of TBL stimulates group discussion and critical thinking, ...
    • Glioblastoma Segmentation: Comparison of Three Different Software Packages 

      Fyllingen, Even Hovig; Stensjøen, Anne Line; Berntsen, Erik Magnus; Reinertsen, Ingerid; Solheim, Ole (Journal article; Peer reviewed, 2016)
      To facilitate a more widespread use of volumetric tumor segmentation in clinical studies, there is an urgent need for reliable, user-friendly segmentation software. The aim of this study was therefore to compare three ...
    • Intraoperative 3D ultrasound-guided resection of diffuse low-grade gliomas: radiological and clinical results 

      Bø, Hans Kristian; Solheim, Ole; Kvistad, Kjell Arne; Berntsen, Erik Magnus; Torp, Sverre Helge; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Iversen, Daniel Høyer; Unsgård, Geirmund; Jakola, Asgeir S (Peer reviewed; Journal article, 2019)
      OBJECTIVE Extent of resection (EOR) and residual tumor volume are linked to prognosis in low-grade glioma (LGG) and there are various methods for facilitating safe maximal resection in such patients. In this prospective ...
    • Is the anatomical distribution of low-grade gliomas linked to regions of gliogenesis? 

      Skjulsvik, Anne Jarstein; Bø, Hans Kristian; Jakola, Asgeir S; Berntsen, Erik Magnus; Bø, Lars Eirik; Reinertsen, Ingerid; Myrmel, Kristin Smistad; Sjåvik, Kristin; Åberg, Kristin; Berg, Thomas; Hong, Yan Dai; Kloster, Roar; Torp, Sverre Helge; Solheim, Ole (Peer reviewed; Journal article, 2020)
      Introduction According to the stem cell theory, two neurogenic niches in the adult human brain may harbor cells that initiate the formation of gliomas: The larger subventricular zone (SVZ) and the subgranular zone (SGZ) ...
    • MGMT Promoter Methylation Status Is Not Related to Histological or Radiological Features in IDH Wild-type Glioblastomas 

      Mikkelsen, Vilde Elisabeth; Hong, Yan Dai; Stensjøen, Anne Line; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole; Torp, Sverre Helge (Peer reviewed; Journal article, 2020)
      O6-methylguanine DNA methyltransferase (MGMT) promoter methylation is an important favorable predictive marker in patients with glioblastoma (GBM). We hypothesized that MGMT status could be a surrogate marker of pretreatment ...
    • Multimodal 18F-Fluciclovine PET/MRI and Ultrasound-Guided Neurosurgery of an Anaplastic Oligodendroglioma 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Myrthue, Mariane Olesen; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Esmaeili, Morteza; Dai, Hong Yan; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2017)
      Background Structural magnetic resonance imaging (MRI) and histopathologic tissue sampling are routinely performed as part of the diagnostic workup for patients with glioma. Because of the heterogeneous nature of gliomas, ...
    • Normative Data for Brainstem Structures, the Midbrain-to-Pons Ratio, and the Magnetic Resonance Parkinsonism Index 

      Ruiz, Sofia Tønnessen; Bakklund, Rannveig Vangen; Håberg, Asta Kristine; Berntsen, Erik Magnus (Peer reviewed; Journal article, 2022)
      BACKGROUND AND PURPOSE: Imaging biomarkers derived from different brainstem structures are suggested to differentiate among parkinsonian disorders, but clinical implementation requires normative data. The main objective ...
    • Normative data for pituitary size and volume in the general population between 50 and 66 years 

      Berntsen, Erik Magnus; Haukedal, Matias Daleng; Håberg, Asta (Journal article; Peer reviewed, 2021)
      Purpose The main aim of this study was to provide normative data for pituitary height and volume in persons between 50 and 66 years in the general population. The secondary aim was to establish a convenient surrogate marker ...
    • PET/MRI: Performance Characteristics and Diagnostic Assessment in Cerebral Gliomas 

      Karlberg, Anna (Doctoral theses at NTNU;2019:125, Doctoral thesis, 2019)
      Norsk sammendrag Det første positronemisjonstomografi (PET)/magnetisk resonans (MR) systemet i Norge ble installert i Trondheim i september 2013. Dette var en gave til St. Olavs hospital/ Norges teknisk-naturvitenskapelige ...
    • Preoperative Planning and Functional Neuronavigation: with Functional MRI and Diffusion Tensor Tractography in Patients with Brain Lesions 

      Berntsen, Erik Magnus (Doktoravhandlinger ved NTNU, 1503-8181; 2009:242, Doctoral thesis, 2009)
      Blood-Oxygenation-Level-Dependent functional Magnetic-Resonance-Imaging (BOLD fMRI) og Diffusion Tensor Imaging (DTI) er spesialiserte MR-teknikker for avbildning av henholdsvis funksjonelle områder i grå substans og ...
    • Quality learning in undergraduate medical education - Improving teaching and assessment practices 

      Martinsen, Susanne Skjervold Smeby (Doctoral theses at NTNU;2024:88, Doctoral thesis, 2024)
      Although there have been significant advancements in our understanding of human learning over the last century, many educational practices within the medical field have not integrated educational research findings. ...
    • Quantitative and clinical impact of MRI-based attenuation correction methods in[18F]FDG evaluation of dementia 

      Øen, Silje Kjærnes; Keil, Thomas; Berntsen, Erik Magnus; Aanerud, Joel Fredrik; Schwarzlmüller, Thomas; Ladefoged, Claes Nøhr; Karlberg, Anna Maria; Eikenes, Live (Journal article; Peer reviewed, 2019)
      Background Positron emission tomography/magnetic resonance imaging (PET/MRI) is a promising diagnostic imaging tool for the diagnosis of dementia, as PET can add complementary information to the routine imaging examination ...
    • Quantitative texture analysis in the prediction of IDH status in low-grade gliomas 

      Jakola, Asgeir Store; Zang, YH; Skjulsvik, Anne Jarstein; Solheim, Ole; Bø, Hans Kristian; Berntsen, Erik Magnus; Reinertsen, Ingerid; Gulati, Sasha; Förander, Petter; Brismar, Torkel B. (Journal article; Peer reviewed, 2017)
      Objectives Molecular markers provide valuable information about treatment response and prognosis in patients with low-grade gliomas (LGG). In order to make this important information available prior to surgery the aim of ...
    • Radiological considerations in 3D ultrasound guided diffuse low-grade glioma surgery 

      Bø, Hans Kristian (Doctoral theses at NTNU;2019:257, Doctoral thesis, 2019)