• 18F-FACBC PET/MRI in diagnostic assessment and neurosurgery of gliomas 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Hong, Yan Dai; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2019)
      Purpose This pilot study aimed to evaluate the amino acid tracer 18F-FACBC with simultaneous PET/MRI in diagnostic assessment and neurosurgery of gliomas. Materials and Methods Eleven patients with suspected primary or ...
    • Angiogenesis and radiological tumor growth in patients with glioblastoma 

      Mikkelsen, Vilde Elisabeth; Stensjøen, Anne Line; Granli, Unn Sophie; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole; Torp, Sverre Helge (Journal article; Peer reviewed, 2018)
      Background The preoperative growth of human glioblastomas (GBMs) has been shown to vary among patients. In animal studies, angiogenesis has been linked to hypoxia and faster growth of GBM, however, its relation to the ...
    • Glioblastoma Segmentation: Comparison of Three Different Software Packages 

      Fyllingen, Even Hovig; Stensjøen, Anne Line; Berntsen, Erik Magnus; Reinertsen, Ingerid; Solheim, Ole (Journal article; Peer reviewed, 2016)
      To facilitate a more widespread use of volumetric tumor segmentation in clinical studies, there is an urgent need for reliable, user-friendly segmentation software. The aim of this study was therefore to compare three ...
    • Intraoperative 3D ultrasound-guided resection of diffuse low-grade gliomas: radiological and clinical results. 

      Bø, Hans Kristian; Solheim, Ole; Kvistad, Kjell Arne; Berntsen, Erik Magnus; Torp, Sverre Helge; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Iversen, Daniel Høyer; Unsgård, Geirmund; Jakola, Asgeir S (Peer reviewed; Journal article, 2019)
      OBJECTIVE Extent of resection (EOR) and residual tumor volume are linked to prognosis in low-grade glioma (LGG) and there are various methods for facilitating safe maximal resection in such patients. In this prospective ...
    • MGMT Promoter Methylation Status Is Not Related to Histological or Radiological Features in IDH Wild-type Glioblastomas 

      Mikkelsen, Vilde Elisabeth; Hong, Yan Dai; Stensjøen, Anne Line; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole; Torp, Sverre Helge (Peer reviewed; Journal article, 2020)
      O6-methylguanine DNA methyltransferase (MGMT) promoter methylation is an important favorable predictive marker in patients with glioblastoma (GBM). We hypothesized that MGMT status could be a surrogate marker of pretreatment ...
    • Multimodal 18F-Fluciclovine PET/MRI and Ultrasound-Guided Neurosurgery of an Anaplastic Oligodendroglioma 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Myrthue, Mariane Olesen; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Esmaeili, Morteza; Dai, Hong Yan; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2017)
      Background Structural magnetic resonance imaging (MRI) and histopathologic tissue sampling are routinely performed as part of the diagnostic workup for patients with glioma. Because of the heterogeneous nature of gliomas, ...
    • PET/MRI: Performance Characteristics and Diagnostic Assessment in Cerebral Gliomas 

      Karlberg, Anna (Doctoral theses at NTNU;2019:125, Doctoral thesis, 2019)
      Norsk sammendrag Det første positronemisjonstomografi (PET)/magnetisk resonans (MR) systemet i Norge ble installert i Trondheim i september 2013. Dette var en gave til St. Olavs hospital/ Norges teknisk-naturvitenskapelige ...
    • Preoperative Planning and Functional Neuronavigation: with Functional MRI and Diffusion Tensor Tractography in Patients with Brain Lesions 

      Berntsen, Erik Magnus (Doktoravhandlinger ved NTNU, 1503-8181; 2009:242, Doctoral thesis, 2009)
      Blood-Oxygenation-Level-Dependent functional Magnetic-Resonance-Imaging (BOLD fMRI) og Diffusion Tensor Imaging (DTI) er spesialiserte MR-teknikker for avbildning av henholdsvis funksjonelle områder i grå substans og ...
    • Quantitative and clinical impact of MRI-based attenuation correction methods in[18F]FDG evaluation of dementia 

      Øen, Silje Kjærnes; Keil, Thomas; Berntsen, Erik Magnus; Aanerud, Joel Fredrik; Schwarzlmüller, Thomas; Ladefoged, Claes Nøhr; Karlberg, Anna Maria; Eikenes, Live (Journal article; Peer reviewed, 2019)
      Background Positron emission tomography/magnetic resonance imaging (PET/MRI) is a promising diagnostic imaging tool for the diagnosis of dementia, as PET can add complementary information to the routine imaging examination ...
    • Quantitative texture analysis in the prediction of IDH status in low-grade gliomas 

      Jakola, Asgeir Store; Zang, YH; Skjulsvik, Anne Jarstein; Solheim, Ole; Bø, Hans Kristian; Berntsen, Erik Magnus; Reinertsen, Ingerid; Gulati, Sasha; Förander, Petter; Brismar, Torkel B. (Journal article; Peer reviewed, 2017)
      Objectives Molecular markers provide valuable information about treatment response and prognosis in patients with low-grade gliomas (LGG). In order to make this important information available prior to surgery the aim of ...
    • Radiological considerations in 3D ultrasound guided diffuse low-grade glioma surgery 

      Bø, Hans Kristian (Doctoral theses at NTNU;2019:257, Doctoral thesis, 2019)
    • Radiologisk vekstmåling av glioblastomer 

      Langlo, Maren Staurset; Simonsen, Solveig Quam (Master thesis, 2016)
      Bakgrunn: Anbefalt metode for bedømming av vekst av glioblastomer er i dag todimensjonale mål i henhold til RANO-kriteriene. En viktig svakhet ved denne metoden er at den bruker todimensjonale mål på en irregulær tredimensjonal ...
    • Surgically acquired deficits and diffusion weighted MRI changes after glioma resection - A matched case-control study with blinded neuroradiological assessment 

      Jakola, Asgeir S; Berntsen, Erik Magnus; Christensen, Pål; Gulati, Sasha; Unsgård, Geirmund; Kvistad, Kjell Arne; Solheim, Ole (Journal article; Peer reviewed, 2014)
      Background: Acquired deficits following glioma resection may not only occur due to accidental resection of normal brain tissue. The possible importance of ischemic injuries in causing neurological deficits after brain ...
    • The Direction of Tumour Growth in Glioblastoma Patients 

      Esmaeili, Morteza; Stensjøen, Anne Line; Berntsen, Erik Magnus; Solheim, Ole; Reinertsen, Ingerid (Journal article; Peer reviewed, 2018)
      Generating MR-derived growth pattern models for glioblastoma multiforme (GBM) has been an attractive approach in neuro-oncology, suggesting a distinct pattern of lesion spread with a tendency in growing along the white ...