• Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform 

      Berges, Natalia; Nawaz, Meh Sameen; Dahl, Tuva Børresdatter; Hagen, Lars; Bjørås, Magnar; Lærdahl, Jon Kristen; Alseth, Ingrun (Journal article; Peer reviewed, 2019)
      Endonuclease V (ENDOV) is a ribonuclease with affinity for inosine which is the deamination product of adenosine. The genomes of most organisms, including human, encode ENDOV homologs, yet knowledge about in vivo functions ...
    • Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma 

      Kong, Xiang Yi; Vik, Erik Sebastian; Nawaz, Meh Sameen; Berges, Natalia; Dahl, Tuva Børresdatter; Vågbø, Cathrine; Suganthan, Rajikala; Segers, Filip; Holm, Sverre; Quiles-Jimenez, Ana; Gregersen, Ida; Fladeby, Cathrine; Aukrust, Pål; Bjørås, Magnar; Klungland, Arne; Halvorsen, Bente; Alseth, Ingrun (Peer reviewed; Journal article, 2020)
      Endonuclease V (EndoV) is a conserved inosine-specific ribonuclease with unknown biological function. Here, we present the first mouse model lacking EndoV, which is viable without visible abnormalities. We show that ...