Browsing NTNU Open by Author "Ben-Shlomo, Yoav"
Now showing items 1-6 of 6
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Antidepressants in pregnancy: applying causal epidemiological methods to understand service-use outcomes in women and long-term neurodevelopmental outcomes in exposed children
Heuvelman, Hein; Davies, Neil Martin; Ben-Shlomo, Yoav; Emond, Alan; Evans, Jonathan; Gunnell, David; Liebling, Rachel; Morris, Richard; Payne, Rupert; Storey, Claire; Viner, Maria; Rai, Dheeraj (Journal article; Peer reviewed, 2023) -
The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization
Korologou-Linden, Roxanna; Bhatta, Laxmi; Brumpton, Ben Michael; Howe, Laura D.; Millard, Louise A. C.; Kolaric, Katarina; Ben-Shlomo, Yoav; Williams, Dylan M.; Smith, George Davey; Anderson, Emma L.; Stergiakouli, Evie; Davies, Neil Martin (Peer reviewed; Journal article, 2022)Alzheimer’s disease (AD) has no proven causal and modifiable risk factors, or effective interventions. We report a phenome-wide association study (PheWAS) of genetic liability for AD in 334,968 participants of the UK Biobank ... -
Heavier smoking may lead to a relative increase in waist circumference: Evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium
Morris, Richard W.; Taylor, Amy E.; Fluharty, Meg E.; Bjørngaard, Johan Håkon; Åsvold, Bjørn Olav; Gabrielsen, Maiken Elvestad; Campbell, Archie; Marioni, Riccardo; Kumari, Meena; Korhonen, Tellervo; Männistö, Satu; Marques-Vidal, Pedro; Kaakinen, Marika; Cavadino, Alana; Postmus, Iris; Husemoen, Lise Lotte N.; Skaaby, Tea; Ahluwalia, Tarun Veer Singh; Treur, Jorien L.; Willemsen, Gonneke; Dale, Caroline; Wannamethee, S. Goya; Lahti, Jari; Palotie, Aarno; Räikkönen, Katri; McConnachie, Alex; Padmanabhan, Sandosh; Wong, Andrew; Dalgård, Christine; Paternoster, Lavinia; Ben-Shlomo, Yoav; Tyrrell, Jessica; Horwood, John; Fergusson, David M.; Kennedy, Martin A.; Nohr, Ellen A.; Christiansen, Lene; Kyvik, Kirsten Ohm; Kuh, Diana; Watt, Graham; Eriksson, Johan G.; Whincup, Peter H.; Vink, Jacqueline M.; Boomsma, Dorret I.; Smith, George Davey; Lawlor, Debbie; Linneberg, Allan; Ford, Ian; Jukema, J. Wouter; Power, Chris; Hyppönen, Elina; Jarvelin, Marjo-Riitta; Preisig, Martin; Borodulin, Katja; Kaprio, Jaakko; Kivimaki, Mika; Smith, Blair H.; Hayward, Caroline; Romundstad, Pål Richard; Sørensen, Thorkild I.A.; Munafo, Marcus R.; Sattar, Naveed (Journal article; Peer reviewed, 2015)Objectives: To investigate, using a Mendelian randomisation approach, whether heavier smoking is associated with a range of regional adiposity phenotypes, in particular those related to abdominal adiposity. Design: ... -
Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium
Taylor, Amy E; Fluharty, Meg; Bjørngaard, Johan Håkon; Gabrielsen, Maiken Elvestad; Skorpen, Frank; Marioni, Riccardo R.; Campbell, A.; Engmann, J; Mirza, Saira Saeed; Loukola, A.; Laatikainen, Tiina; Partonen, Timo; Kaakinen, Marika; Ducci, Francesca; Cavadino, Alana; Husemoen, Lise Lotte N; Ahluwalia, Tarunveer Singh; Jacobsen, Rikke Kart; Skaaby, Tea; Ebstrup, Jeanette Frost; Mortensen, Erik Lykke; Minica, Camelia C; Vink, Jacqueline; Willemsen, Gonneke; Marques-Vidal, Pedro; Dale, Caroline E; Amuzu, Antoinette; Lennon, Lucy; Lahti, J; Palotie, Aarno; Räikkönen, K; Wong, Andrew; Paternoster, Lavinia; Wong, Angelita Pui-Yee; Horwood, L John; Murphy, Michael; Johnstone, Elaine; Kennedy, Martin A; Pausova, Zdenka; Paus, Tomas; Ben-Shlomo, Yoav; Nohr, Ellen A; Kuh, Diana; Kivimaki, Mika; Eriksson, Johan G; Morris, Richard W; Casas, Juan Pablo; Preisig, Martin; Boomsma, Dorret I; Linneberg, Allan; Power, Chris; Hypponen, Elina; Veijola, J; Järvelin, Marjo-Riitta; Korhonen, T.; Tiemeier, H; Kumari, Meena; Porteous, David J.; Hayward, Caroline; Romundstad, Pål Richard; Smith, George Davey; Munafo, Marcus R (Journal article; Peer reviewed, 2014)Objectives: To investigate whether associations of smoking with depression and anxiety are likely to be causal, using a Mendelian randomisation approach. Design: Mendelian randomisation meta-analyses using a genetic ... -
Is disrupted sleep a risk factor for Alzheimer's disease? Evidence from a two-sample Mendelian randomization analysis
Anderson, Emma L.; Richmond, Rebecca C.; Jones, Samuel E.; Hemani, Gibran; Wade, Kaitlin H; Dashti, Hassan S.; Lane, Jaqueline; Wang, Heming; Saxena, Richa; Brumpton, Ben Michael; Korologou-Linden, Roxanna; Nielsen, Jonas Bille; Åsvold, Bjørn Olav; Abecasis, Goncalo; Coulthard, Elizabeth; Kyle, Simon D.; Beaumont, Robin N.; Tyrell, Jessica; Frayling, Timothy M; Munafo, Marcus R; Wood, Andrew R; Ben-Shlomo, Yoav; Howe, Laura D; Lawlor, Deborah A.; Weedon, Michael N; Smith, George Davey (Peer reviewed; Journal article, 2020)Background It is established that Alzheimer’s disease (AD) patients experience sleep disruption. However, it remains unknown whether disruption in the quantity, quality or timing of sleep is a risk factor for the onset ... -
Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers
Taylor, Amy E; Morris, Richard W; Fluharty, Meg; Bjørngaard, Johan Håkon; Åsvold, Bjørn Olav; Gabrielsen, Maiken Elvestad; Campbell, A.; Marioni, Riccardo R.; Kumari, Meena; Hällfors, Jenni; Männistö, Satu; Marques-Vidal, Pedro; Kaakinen, Marika; Cavadino, Alana; Postmus, Iris; Husemoen, Lise Lotte N; Skaaby, Tea; Ahluwalia, Tarunveer Singh; Treur, Jorien L; Willemsen, Gonneke; Dale, Caroline; Wannamethee, SG; Lahti, J; Palotie, Aarno; Räikkönen, K; Kisialiou, Aliaksei; McConnachie, Alex; Padmanabhan, Sandosh; Wong, Andrew; Dalgård, Christine; Paternoster, Lavinia; Ben-Shlomo, Yoav; Tyrrell, Jessica; Horwood, John; Fergusson, D; Kennedy, Martin A; Frayling, T; Nohr, Ellen A; Christiansen, Lene; Ohm Kyvik, K; Kuh, Diana; Watt, Graham; Eriksson, Johan; Whincup, Peter H; Vink, JM; Boomsma, Dorret I; Davey Smith, George; Lawlor, Debbie A; Linneberg, Allan; Ford, Ian; Jukema, J Wouter; Power, C; Hyppönen, E; Jarvelin, Marjo-Riitta; Preisig, Martin; Borodulin, Katja; Kaprio, Jaakko; Kivimaki, Mika; Smith, BH; Hayward, Caroline; Romundstad, Pål Richard; Sørensen, Thorkild I.A.; Munafo, Marcus R; Sattar, Naveed (Journal article; Peer reviewed, 2014)We previously used a single nucleotide polymorphism (SNP) in the CHRNA5-A3-B4 gene cluster associated with heaviness of smoking within smokers to confirm the causal effect of smoking in reducing body mass index (BMI) in a ...