Browsing NTNU Open by Author "Beisland, Christian"
Now showing items 1-6 of 6
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Expanding the utilization of formalin-fixed, paraffin-embedded archives: Feasibility of miR-Seq for disease exploration and biomarker development from biopsies with clear cell renal cell Carcinoma
Strauss, Philipp; Marti, Hans-Peter; Beisland, Christian; Scherer, Andreas; Lysne, Vegard; Leh, Sabine Maria; Flatberg, Arnar; Koch, Even Evjen; Beisvag, Vidar; Landolt, Lea Zoe; Skogstrand, Trude; Eikrem, Øystein Solberg (Journal article; Peer reviewed, 2018)Novel predictive tools for clear cell renal cell carcinoma (ccRCC) are urgently needed. MicroRNAs (miRNAs) have been increasingly investigated for their predictive value, and formalin-fixed paraffin-embedded biopsy archives ... -
Fine needle aspirates of kidneys: A promising tool for RNA sequencing in native and transplanted kidneys
Eikrem, Øystein Solberg; Walther, Tedd Christian; Flatberg, Arnar; Beisvag, Vidar; Strauss, Philipp; Farstad, Magnus; Beisland, Christian; Koch, Even; Mueller, Thomas F.; Marti, Hans-Peter (Journal article; Peer reviewed, 2018)Background Transcriptome analysis is emerging as emerging as a promising tool to enhance precision of diagnosis and monitoring in solid organ transplantation. Clinical progress has however been hampered by the current ... -
Identifying possible biomarkers of lower urinary tract symptoms using metabolomics and partial least square regression
Hopland-Nechita, Florin Vasile; Andersen, John Roger; Rajalahti, Tarja; Andreassen, Trygve; Beisland, Christian (Peer reviewed; Journal article, 2023)Introduction The objective of this study was to explore potential novel biomarkers for moderate to severe lower urinary tract symptoms (LUTS) using a metabolomics-based approach, and statistical methods with significant ... -
Impact of prebiopsy MRI on prostate cancer staging: Results from the Norwegian Prostate Cancer Registry
Haug, Erik Skaaheim; Myklebust, Tor Åge; Juliebø-Jones, Patrick; Reisæter, Lars Anders Rokne; Aas, Kirsti; Berg, Arne Stenrud; Muller, Christoph Rainer; Hofmann, Bjørn Morten; Størkersen, Øystein; Nilsen, Kim L.; Johannessen, Tom Børge; Beisland, Christian (Peer reviewed; Journal article, 2023)The aim of this study is to evaluate the 2015 introduction of prebiopsy magnetic resonance imaging of the prostate (MRI-P) as the standard of care for diagnosing prostate cancer (PCa) by the Norwegian public health care ... -
A multiomics disease progression signature of low-risk ccRCC
Strauss, Philipp; Rivedal, Mariell; Scherer, Andreas; Eikrem, Øystein Solberg; Nakken, Sigrid; Beisland, Christian; Bostad, Leif; Flatberg, Arnar; Skandalou, Eleni; Beisvag, Vidar; Furriol, Jessica; Marti, Hans Peter (Peer reviewed; Journal article, 2022)Clear cell renal cell carcinoma (ccRCC) is the most common renal cancer. Identification of ccRCC likely to progress, despite an apparent low risk at the time of surgery, represents a key clinical issue. From a cohort of ... -
Transcriptome sequencing (RNAseq) enables utilization of formalin-fixed, paraffin-embedded biopsies with clear cell renal cell carcinoma for exploration of disease biology and biomarker development
Hjelle, Karin Margrethe; Landolt, Lea Zoe; Leh, Sabine Maria; Marti, Hans-Peter; Beisland, Christian; Scherer, Andreas; Skogstrand, Trude; Beisvag, Vidar; Eikrem, Øystein Solberg; Flatberg, Arnar (Journal article; Peer reviewed, 2016)Formalin-fixed, paraffin-embedded (FFPE) tissues are an underused resource for molecular analyses. This proof of concept study aimed to compare RNAseq results from FFPE biopsies with the corresponding RNAlater® (Qiagen, ...