• The Adapted Lifestyle-Integrated Functional Exercise Program for Preventing Functional Decline in Young Seniors: Development and Initial Evaluation 

      Schwenk, Michael; Bergquist, Ronny; Boulton, Elisabeth; Van Ancum, Jeanine M.; Nerz, Corinna; Weber, Michaela; Barz, Carolin; Jonkman, Nini H.; Taraldsen, Kristin; Helbostad, Jorunn L.; Vereijken, Beatrix; Pijnappels, Mirjam; Maier, Andrea B.; Zhang, Wei; Becker, Clemens; Todd, Chris; Clemson, Lindy; Hawley-Hague, H. (Peer reviewed; Journal article, 2019)
      Background: The Lifestyle-integrated Functional Exercise (LiFE) program is an intervention integrating balance and strength activities into daily life, effective at reducing falls in at-risk people ≥70 years. There is ...
    • Assessing real-world gait with digital technology? Validation, insights and recommendations from the Mobilise-D consortium 

      Micó-Amigo, M. Encarna; Bonci, Tecla; Paraschiv-Ionescu, Anisoara; Ullrich, Martin; Kirk, Cameron; Soltani, Abolfazl; Küderle, Arne; Gazit, Eran; Salis, Francesca; Alcock, Lisa; Aminian, Kamiar; Becker, Clemens; Bertuletti, Stefano; Brown, Philip; Buckley, Ellen; Cantu, Alma; Carsin, Anne-Elie; Caruso, Marco; Caulfield, Brian; Cereatti, Andrea; Chiari, Lorenzo; D’Ascanio, Ilaria; Eskofier, Bjoern; Fernstad, Sara; Froehlich, Marcel; Garcia-Aymerich, Judith; Hansen, Clint; Hausdorff, Jeffrey M.; Hiden, Hugo; Hume, Emily; Keogh, Alison; Kluge, Felix; Koch, Sarah; Maetzler, Walter; Megaritis, Dimitrios; Mueller, Arne; Niessen, Martijn; Palmerini, Luca; Schwickert, Lars; Scott, Kirsty; Sharrack, Basil; Sillén, Henrik; Singleton, David; Vereijken, Beatrix; Vogiatzis, Ioannis; Yarnall, Alison J.; Rochester, Lynn; Mazzà, Claudia; Del Din, Silvia (Peer reviewed; Journal article, 2023)
      Background Although digital mobility outcomes (DMOs) can be readily calculated from real-world data collected with wearable devices and ad-hoc algorithms, technical validation is still required. The aim of this paper ...
    • Association between vestibulo-ocular reflex suppression, balance, gait, and fall risk in ageing and neurodegenerative disease: Protocol of a one-year prospective follow-up study 

      Srulijes, Karin; Mack, David J; Klenk, Jochen; Schwickert, Lars; Ihlen, Espen Alexander F.; Schwenk, Michael; Lindemann, Ulrich; Meyer, Miriam; KC, Srijana; Hobert, Markus A; Brockmann, Kathrin; Wurster, Isabel; Pomper, Jörn K; Synofzik, Matthis; Schneider, Erich; Ilg, Uwe; Berg, Daniela; Maetzler, Walter; Becker, Clemens (Peer reviewed; Journal article, 2015)
      Background Falls frequency increases with age and particularly in neurogeriatric cohorts. The interplay between eye movements and locomotion may contribute substantially to the occurrence of falls, but is hardly ...
    • The association of basic and challenging motor capacity with mobility performance and falls in young seniors 

      Gordt, Katharina; Paraschiv-Ionescu, Anisoara; Mikolaizak, A. Stefanie; Taraldsen, Kristin; Mellone, Sabato; Bergquist, Ronny; Van Ancum, Jeanine M.; Nerz, Corinna; Pijnappels, Mirjam; Maier, Andrea B.; Helbostad, Jorunn L.; Vereijken, Beatrix; Becker, Clemens; Aminian, Kamiar; Schwenk, Michael (Peer reviewed; Journal article, 2020)
      Background Understanding the association between motor capacity (MC) (what people can do in a standardized environment), mobility performance (MP) (what people actually do in real-life) and falls is important for early ...
    • Attitudes Towards Adapted Lifestyle-Integrated Functional Exercise Developed for 60-70-Year-Olds: Perceptions of Participants and Trainers 

      Boulton, Elisabeth; Weber, Michaela; Hawley-Hague, Helen; Bergquist, Ronny; Van Ancum, Jeanine M.; Jonkman, Nini H.; Taraldsen, Kristin; Helbostad, Jorunn L.; Maier, Andrea B.; Becker, Clemens; Todd, Chris; Clemson, Lindy; Schwenk, Michael (Journal article; Peer reviewed, 2019)
      Background: Time commitments, limited access, or unwillingness to join a group are some of the many reasons for low adherence to structured exercise in older adults. A promising alternative approach is integrating exercise ...
    • Change of physical activity parameters of hip and pelvic fracture patients during inpatient rehabilitation and after discharge: analysis of global and in-depth parameters 

      Kampe, Karin; Pfeiffer, Klaus; Lindemann, Ulrich; Schoene, Daniel; Taraldsen, Kristin; Rapp, Kilian; Becker, Clemens; Klenk, Jochen (Peer reviewed; Journal article, 2021)
      Background A growing number of older adults suffer hip and pelvic fractures leading to hospital admission. They often result in reduced physical activity (PA) and impaired mobility. PA can be objectively measured with ...
    • Concurrent validity and reliability of the Community Balance and Mobility Scale in young-older adults. 

      Weber, Michaela; Van Ancum, Jeanine M.; Bergquist, Ronny; Taraldsen, Kristin; Gordt, Katharina; Mikolaizak, A. Stefanie; Nerz, Corinna; Pijnappels, Mirjam; Jonkman, Nini H.; Maier, Andrea B.; Helbostad, Jorunn L.; Vereijken, Beatrix; Becker, Clemens; Schwenk, Michael (Journal article; Peer reviewed, 2018)
      Background With the growing number of young-older adults (baby-boomers), there is an increasing demand for assessment tools specific for this population, which are able to detect subtle balance and mobility deficits. ...
    • Connecting real-world digital mobility assessment to clinical outcomes for regulatory and clinical endorsement–the Mobilise-D study protocol 

      Mikolaizak, A. Stefanie; Rochester, Lynn; Maetzler, Walter; Sharrack, Basil; Demeyer, Heleen; Mazzà, Claudia; Caulfield, Brian; Garcia-Aymerich, Judith; Vereijken, Beatrix; Arnera, Valdo; Miller, Ram; Piraino, Paolo; Ammour, Nadir; Gordon, Mark Forrest; Troosters, Thierry; Yarnall, Alison J.; Alcock, Lisa; Gaßner, Heiko; Winkler, Jürgen; Klucken, Jochen; Schlenstedt, Christian; Watz, Henrik; Kirsten, Anne-Marie; Vogiatzis, Ioannis; Chynkiamis, Nikolaos; Hume, Emily; Megaritis, Dimitrios; Nieuwboer, Alice; Ginis, Pieter; Buckley, Ellen; Brittain, Gavin; Comi, Giancarlo; Leocani, Letizia; Helbostad, Jorunn L.; Johnsen, Lars Gunnar; Taraldsen, Kristin; Blain, Hubert; Driss, Valérie; Frei, Anja; Puhan, Milo A.; Polhemus, Ashley; de Basea, Magda Bosch; Gimeno, Elena; Hopkinson, Nicholas S.; Buttery, Sara C.; Hausdorff, Jeffrey M.; Mirelman, Anat; Evers, Jordi; Neatrour, Isabel; Singleton, David; Schwickert, Lars; Becker, Clemens; Jansen, Carl-Philipp (Peer reviewed; Journal article, 2022)
      Background The development of optimal strategies to treat impaired mobility related to ageing and chronic disease requires better ways to detect and measure it. Digital health technology, including body worn sensors, ...
    • Creating and Validating a Shortened Version of the Community Balance and Mobility Scale for Application in People Who Are 61 to 70 Years of Age 

      Gordt, Katharina; Mikolaizak, A. Stefanie; Taraldsen, Kristin; Bergquist, Ronny; Van Ancum, Jeanine M.; Nerz, Corinna; Pijnappels, Mirjam; Maier, Andrea B.; Helbostad, Jorunn L.; Vereijken, Egberta; Becker, Clemens; Schwenk, Michael (Peer reviewed; Journal article, 2020)
      Background The Community Balance and Mobility Scale (CBM) has been shown to be reliable and valid for detecting subtle balance and mobility deficits in people who are 61 to 70 years of age. However, item redundancy and ...
    • Design and validation of a multi-task, multi-context protocol for real-world gait simulation 

      Scott, Kirsty; Bonci, Tecla; Salis, Francesca; Alcock, Lisa; Buckley, Ellen; Gazit, Eran; Hansen, Clint; Schwickert, Lars; Aminian, Kamiar; Bertuletti, Stefano; Caruso, Marco; Chiari, Lorenzo; Sharrack, Basil; Maetzler, Walter; Becker, Clemens; Hausdorff, Jeffrey M.; Vogiatzis, Ioannis; Brown, Philip; Del Din, Silvia; Eskofier, Björn; Paraschiv-Ionescu, Anisoara; Keogh, Alison; Kirk, Cameron; Kluge, Felix; Micó-Amigo, Encarna M.; Mueller, Arne; Neatrour, Isabel; Niessen, Martijn; Palmerini, Luca; Sillen, Henrik; Singleton, David; Ullrich, Martin; Vereijken, Beatrix; Froehlich, Marcel; Brittain, Gavin; Caulfield, Brian; Koch, Sarah; Carsin, Anne-Elie; Garcia-Aymerich, Judith; Kuederle, Arne; Yarnall, Alison; Rochester, Lynn; Cereatti, Andrea; Mazzà, Claudia (Peer reviewed; Journal article, 2022)
      Background Measuring mobility in daily life entails dealing with confounding factors arising from multiple sources, including pathological characteristics, patient specific walking strategies, environment/context, and ...
    • Digital technology to deliver a lifestyle-integrated exercise intervention in young seniors – the PreventIT feasibility randomised controlled trial 

      Taraldsen, Kristin; Mikolaizak, A. Stefanie; Maier, Andrea B.; Mellone, Sabato; Boulton, Elisabeth; Aminian, Kamiar; Becker, Clemens; Chiari, Lorenzo; Follestad, Turid; Gannon, Brenda; Ionescu, Anisoara; Pijnappels, Mirjam; Saltvedt, Ingvild; Schwenk, Michael; Todd, Chris; Yang, Fan Bella; Zacchi, Anna; Van Ancum, Jeanine M.; Vereijken, Beatrix; Helbostad, Jorunn L. (Peer reviewed; Journal article, 2020)
      Background: Behavioral change is the key to alter individuals’ lifestyle from sedentary to active. The aim was to assess the feasibility of delivering a Lifestyle-integrated Functional Exercise programme and evaluate the ...
    • Ecological validity of a deep learning algorithm to detect gait events from real-life walking bouts in mobility-limiting diseases 

      Romijnders, Robbin; Salis, Francesca; Hansen, Clint; Küderle, Arne; Paraschiv-Ionescu, Anisoara; Cereatti, Andrea; Alcock, Lisa; Aminian, Kamiar; Becker, Clemens; Bertuletti, Stefano; Bonci, Tecla; Brown, Philip; Buckley, Ellen; Cantu, Alma; Carsin, Anne-Elie; Caruso, Marco; Caulfield, Brian; Chiari, Lorenzo; D'Ascanio, Ilaria; Del Din, Silvia; Eskofier, Björn; Fernstad, Sara Johansson; Fröhlich, Marceli Stanislaw; Garcia Aymerich, Judith; Gazit, Eran; Hausdorff, Jeffrey M.; Hiden, Hugo; Hume, Emily; Keogh, Alison; Kirk, Cameron; Kluge, Felix; Koch, Sarah; Mazzà, Claudia; Megaritis, Dimitrios; Micó-Amigo, Encarna; Müller, Arne; Palmerini, Luca; Rochester, Lynn; Schwickert, Lars; Scott, Kirsty; Sharrack, Basil; Singleton, David; Soltani, Abolfazl; Ullrich, Martin; Vereijken, Beatrix; Vogiatzis, Ioannis; Yarnall, Alison; Schmidt, Gerhard; Maetzler, Walter (Peer reviewed; Journal article, 2023)
      Introduction: The clinical assessment of mobility, and walking specifically, is still mainly based on functional tests that lack ecological validity. Thanks to inertial measurement units (IMUs), gait analysis is shifting ...
    • The FARSEEING real-world fall repository: a large-scale collaborative database to collect and share sensor signals from real-world falls 

      Klenk, Jochen; Schwickert, Lars; Palmerini, Luca; Mellone, Sabato; Bourke, Alan; Ihlen, Espen Alexander F.; Kerse, Ngaire; Hauer, Klaus; Pijnappels, Mirjam; Synofzik, Matthis; Srulijes, Karin; Maetzler, Walter; Helbostad, Jorunn L.; Zijlstra, Wiebren; Aminian, Kamiar; Todd, Christopher; Chiari, Lorenzo; Becker, Clemens (Peer reviewed; Journal article, 2016)
      Background Real-world fall events objectively measured by body-worn sensors can improve the understanding of fall events in older people. However, these events are rare and hence challenging to capture. Therefore, the ...
    • Impact of adherence to a lifestyle-integrated programme on physical function and behavioural complexity in young older adults at risk of functional decline: a multicentre RCT secondary analysis 

      Mikolaizak, A Stefanie; Taraldsen, Kristin; Boulton, Elisabeth; Gordt, Katharina; Maier, Andrea Britta; Mellone, Sabato; Hawley-Hague, Helen; Aminian, Kamiar; Chiari, Lorenzo; Paraschiv-Ionescu, Anisoara; Pijnappels, Mirjam; Todd, Chris; Vereijken, Beatrix; Helbostad, Jorunn L.; Becker, Clemens (Peer reviewed; Journal article, 2022)
      Context Long-term adherence to physical activity (PA) interventions is challenging. The Lifestyle-integrated Functional Exercise programmes were adapted Lifestyle-integrated Functional Exercise (aLiFE) to include more ...
    • Inertial sensor based analysis of lie-to-stand transfers in younger and older adults 

      Schwickert, Lars; Boos, Ronald; Klenk, Jochen; Bourke, Alan; Becker, Clemens; Zijlstra, Wiebren (Journal article; Peer reviewed, 2016)
      Many older adults lack the capacity to stand up again after a fall. Therefore, to analyse falls it is relevant to understand recovery patterns, including successful and failed attempts to get up from the floor in general. ...
    • Laboratory and free-living gait performance in adults with COPD and healthy controls 

      Buekers, Joren; Megaritis, Dimitrios; Koch, Sarah; Alcock, Lisa; Ammour, Nadir; Becker, Clemens; Bertuletti, Stefano; Bonci, Tecla; Brown, Philip; Buckley, Ellen; Buttery, Sara C.; Caulfied, Brian; Cereatti, Andrea; Chynkiamis, Nikolaos; Demeyer, Heleen; Echevarria, Carlos; Frei, Anja; Hansen, Clint; Hausdorff, Jeffrey M.; Hopkinson, Nicholas S.; Hume, Emily; Kuederle, Arne; Maetzler, Walter; Mazzà, Claudia; Micó-Amigo, Encarna M.; Mueller, Arne; Palmerini, Luca; Salis, Francesca; Scott, Kirsty; Troosters, Thierry; Vereijken, Beatrix; Watz, Henrik; Rochester, Lynn; Din, Silvia Del; Vogiatzis, Ioannis; Garcia-Aymerich, Judith (Peer reviewed; Journal article, 2023)
      Background Gait characteristics are important risk factors for falls, hospitalisations and mortality in older adults, but the impact of COPD on gait performance remains unclear. We aimed to identify differences in gait ...
    • Mobile health applications to promote active and healthy ageing 

      Helbostad, Jorunn L.; Vereijken, Beatrix; Becker, Clemens; Todd, Chris; Taraldsen, Kristin; Pijnappels, Mirjam; Aminian, Kamair; Mellone, Sabato (Journal article; Peer reviewed, 2017)
      The European population is ageing, and there is a need for health solutions that keep older adults independent longer. With increasing access to mobile technology, such as smartphones and smartwatches, the development and ...
    • A multi-sensor wearable system for the assessment of diseased gait in real-world conditions 

      Salis, Francesca; Bertuletti, Stefano; Bonci, Tecla; Caruso, Marco; Scott, Kirsty; Alcock, Lisa; Buckley, Ellen; Gazit, Eran; Hansen, Clint; Schwickert, Lars; Aminian, Kamiar; Becker, Clemens; Brown, Philip; Carsin, Anne-Elie; Caulfield, Brian; Chiari, Lorenzo; D’Ascanio, Ilaria; Del Din, Silvia; Eskofier, Bjoern M.; Garcia-Aymerich, Judith; Hausdorff, Jeffrey M.; Hume, Emily C.; Kirk, Cameron; Kluge, Felix; Koch, Sarah; Kuederle, Arne; Maetzler, Walter; Micó-Amigo, Encarna M.; Mueller, Arne; Neatrour, Isabel; Paraschiv-Ionescu, Anisoara; Palmerini, Luca; Yarnall, Alison J.; Rochester, Lynn; Sharrack, Basil; Singleton, David; Vereijken, Beatrix; Vogiatzis, Ioannis; Della Croce, Ugo; Mazzà, Claudia; Cereatti, Andrea (Peer reviewed; Journal article, 2023)
      Introduction: Accurately assessing people’s gait, especially in real-world conditions and in case of impaired mobility, is still a challenge due to intrinsic and extrinsic factors resulting in gait complexity. To improve ...
    • On the use of wearable sensors as mobility biomarkers in the marketing authorization of new drugs: A regulatory perspective 

      Viceconti, Marco; Tome, M.; Dartee, Wim P; Knezevic, I.; Hernandez Penna, S.; Mazzà, Claudia; Caulfield, Brian; Garcia-Aymerich, Judith; Becker, Clemens; Maetzler, Walter; Troosters, Thierry; Sharrack, Basil; Davico, Giorgio; Corriol-Rohou, Solange; Rochester, Lynn; Mobilise-D, Consortium; Vereijken, Beatrix (Peer reviewed; Journal article, 2022)
      The loss of mobility is a common trait in multiple health conditions (e.g., Parkinson's disease) and is associated with reduced quality of life. In this context, being able to monitor mobility in the real world, is important. ...
    • Predicting Advanced Balance Ability and Mobility with an Instrumented Timed Up and Go Test 

      Bergquist, Ronny; Nerz, Corinna; Taraldsen, Kristin; Mellone, Sabato; Ihlen, Espen Alexander F.; Vereijken, Beatrix; Helbostad, Jorunn L.; Becker, Clemens; Mikolaizak, A. Stefanie (Peer reviewed; Journal article, 2020)
      Extensive test batteries are often needed to obtain a comprehensive picture of a person’s functional status. Many test batteries are not suitable for active and healthy adults due to ceiling effects, or require a lot of ...