Blar i NTNU Open på forfatter "Baracos, Vickie"

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    • A prospective study examining cachexia predictors in patients with incurable cancer 

      Vagnildhaug, Ola Magne; Brunelli, Cinzia; Hjermstad, Marianne Jensen; Strasser, Florian; Baracos, Vickie; Wilcock, Andrew; Nabal, María; Kaasa, Stein; Laird, Barry J; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2019)
      Background Early intervention against cachexia necessitates a predictive model. The aims of this study were to identify predictors of cachexia development and to create and evaluate accuracy of a predictive model based ...

    • Cancer cachexia: Rationale for the MENAC (Multimodal - Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial 

      Solheim, Tora Skeidsvoll; Laird, Barry J. A.; Balstad, Trude Rakel; Bye, Asta; Stene, Guro Birgitte; Baracos, Vickie; Strasser, Florian; Griffiths, Gareth; Maddocks, Matthew; Fallon, Marie; Kaasa, Stein; Fearon, Kenneth (Journal article; Peer reviewed, 2018)
      Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support alone. Cachexia has a high prevalence in cancer and a ...

    • ESPEN guidelines on nutrition in cancer patients 

      Arends, Jann; Bachmann, Peter; Baracos, Vickie; Barthelemy, N; Bertz, H; Bozzetti, Frederico; Fearon, KC; Hütterer, E; Isenring, E; Kaasa, Stein; Krznaric, Z; Laird, Barry J.; Larsson, M; Laviano, A; Mühlebach, S; Muscaritoli, Maurizio; Oldervoll, Line Merethe; Ravasco, Paula; Solheim, Tora Skeidsvoll; Strasser, Florian; de van der Schueren, Marian; Preiser, JC (Journal article; Peer reviewed, 2017)
      Cancers are among the leading causes of morbidity and mortality worldwide, and the number of new cases is expected to rise significantly over the next decades. At the same time, all types of cancer treatment, such as ...

    • Is there a genetic cause of appetite loss? - An explorative study in 1853 cancer patients 

      Solheim, Tora Skeidsvoll; Fayers, Peter; Fladvad, Torill; Tan, Ben; Skorpen, Frank; Fearon, Kenneth C.; Baracos, Vickie; Klepstad, Pål; Strasser, Florian; Kaasa, Stein (Journal article; Peer reviewed, 2012)
      Background Appetite loss has a major impact on cancer patients. It is exceedingly prevalent, is a prognostic indicator and is associated with inferior quality of life. Cachexia is a multi‐factorial syndrome defined by a ...

    • P-selectin genotype is associated with the development of cancer cachexia 

      Tan, Benjamin HL; Fladvad, Torill; Braun, TP; Vigano, Antonio A.L.; Strasser, Florian; Deans, DAC; Skipworth, R.J.; Skeidsvoll, Tora Lång; Damaraju, S; Ross, JA; Kaasa, Stein; Marks, DL; Baracos, Vickie; Skorpen, Frank; Fearon, Kenneth C. (Journal article; Peer reviewed, 2012)
      The variable predisposition to cachexia may, in part, be due to the interaction of host genotype. We analyzed 129 single nucleotide polymorphisms (SNPs) in 80 genes for association with cachexia based on degree of weight ...

    • Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series 

      McDonald, James; Sayers, Judith; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Baracos, Vickie; Brown, Leo; Bye, Asta; Dajani, Olav; Dolan, Ross; Fallon, Marie T.; Fraser, Eilidh; Griel, Christine; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jamal-Hanjani, Mariam; Jakobsen, Gunnhild; Kaasa, Stein; McMillan, Donald; Maddocks, Matthew; Philips, Iain; Ottestad, Inger; Reid, Kieran F.; Sousa, Mariana S.; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Skipworth, Richard J. E.; Solheim, Tora S; Laird, Barry J (Peer reviewed; Journal article, 2023)
      In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, ...