Browsing NTNU Open by Author "Bækkerud, Fredrik Hjulstad"

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    • Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial 

      Smenes, Benedikte; Bækkerud, Fredrik Hjulstad; Slagsvold, Katrine Hordnes; Hassel, Erlend; Wohlwend, Martin; Pinho, Maria; Høydal, Morten; Wisløff, Ulrik; Rognmo, Øivind; Wahba, Alexander (Journal article; Peer reviewed, 2018)
      OBJECTIVES During open-heart surgery, the myocardium experiences ischaemia–reperfusion injury. A single bout of moderate, 30-min exercise induces preconditioning and protects the heart from ischaemia–reperfusion injury ...

    • Effect of 5 years of exercise training on the cardiovascular risk profile of older adults: the Generation 100 randomized trial 

      Letnes, Jon Magne; Berglund, Ida Johnsen; Johnson, Kristin Espolin; Dalen, Håvard; Nes, Bjarne; Lydersen, Stian; Viken, Hallgeir; Hassel, Erlend; Steinshamn, Sigurd Loe; Vesterbekkmo, Elisabeth Kleivhaug; Støylen, Asbjørn; Reitlo, Line Skarsem; Zisko, Nina; Bækkerud, Fredrik Hjulstad; Tari, Atefe R; Ingebrigtsen, Jan Erik; Bucher Sandbakk, Silvana; Carlsen, Trude; Anderssen, Sigmund Alfred; Singh, Maria A. Fiatarone; Coombes, Jeff S.; Helbostad, Jorunn L.; Rognmo, Øivind; Wisløff, Ulrik; Stensvold, Dorthe (Peer reviewed; Journal article, 2021)
      Aims The aim of this study was to compare the effects of 5 years of supervised exercise training (ExComb), and the differential effects of subgroups of high-intensity interval training (HIIT) and moderate-intensity continuous ...

    • Effect of exercise training for five years on all cause mortality in older adults-The Generation 100 study: Randomised controlled trial 

      Stensvold, Dorthe; Viken, Hallgeir; Steinshamn, Sigurd Loe; Dalen, Håvard; Støylen, Asbjørn; Loennechen, Jan Pål; Reitlo, Line Skarsem; Zisko, Nina; Bækkerud, Fredrik Hjulstad; Tari, Atefe R; Bucher Sandbakk, Silvana; Carlsen, Trude; Ingebrigtsen, Jan Erik; Lydersen, Stian; Mattsson, Erney; Anderssen, Sigmund Alfred; Singh, Maria A. Fiatarone; Coombes, Jeff S.; Skogvoll, Eirik; Vatten, Lars Johan; Helbostad, Jorunn L.; Rognmo, Øivind; Wisløff, Ulrik (Peer reviewed; Journal article, 2020)
      Objective To evaluate the effect of five years of supervised exercise training compared with recommendations for physical activity on mortality in older adults (70-77 years). Design Randomised controlled trial. Setting ...

    • Exercise training reveals inflexibility of the diaphragm in an animal model of patients with obesity-driven heart failure with a preserved ejection fraction 

      Bowen, T Scott; Brauer, Dominic; Rolim, Natale Pinheiro Lage; Bækkerud, Fredrik Hjulstad; Kricke, Angela; Berre, Anne Marie Ormbostad; Fischer, Tina; Linke, Axel; Silva, Gustavo Jose Justo; Wisløff, Ulrik; Adams, Volker (Journal article; Peer reviewed, 2017)
      Background Respiratory muscle weakness contributes to exercise intolerance in patients with heart failure with a preserved ejection fraction (HFpEF)—a condition characterized by multiple comorbidities with few proven ...

    • High intensity interval training ameliorates mitochondrial dysfunction in the left ventricle of mice with type 2 diabetes 

      Bækkerud, Fredrik Hjulstad; Salerno, Simona; Ceriotti, Paola; Morland, Cecilie; Storm-Mathisen, Jon; Bergersen, Linda Hildegard; Høydal, Morten; Catalucci, Daniele; Stølen, Tomas (Journal article; Peer reviewed, 2019)
      UNIKARD (Project Number 217777/H10)

    • How to Be 80 Year Old and Have a VO2max of a 35 Year Old 

      Karlsen, Trine; Leinan, Ingeborg Megård; Bækkerud, Fredrik Hjulstad; Lundgren, Kari Margrethe; Tari, Atefe R; Steinshamn, Sigurd Loe; Støylen, Asbjørn; Rognmo, Øivind (Peer reviewed; Journal article, 2015)
      Background. To discuss the cardiovascular and pulmonary physiology and common risk factors of an 80-year-old man with a world record maximal oxygen uptake of 50 mL·kg−1·min−1. Methods. Case report. Results. His maximal ...

    • Mitochondrial Function and Exercise in Cardiovascular Diseases 

      Bækkerud, Fredrik Hjulstad (Doctoral theses at NTNU;2019:221, Doctoral thesis, 2019)
      Kardiovaskulær sykdom er den vanligste dødsårsaken i verden, men epidemiologiske undersøkelser indikerer at trening kan redusere denne dødeligheten. Mekanismene bak den positive effekten av trening på kardiovaskulær helse ...