Browsing NTNU Open by Author "Antignano, Frann"

Now showing items 1-2 of 2

    • Intestinal Epithelial Cell-Intrinsic Deletion of Setd7 Identifies Role for Developmental Pathways in Immunity to Helminth Infection 

      Oudhoff, Menno; Antignano, Frann; Chenery, Alistair L; Burrows, Kyle; Redpath, Stephen A; Braam, Mitchell J; Perona-Wright, Georgia; Zaph, Colby (Journal article; Peer reviewed, 2016)
      The intestine is a common site for a variety of pathogenic infections. Helminth infections continue to be major causes of disease worldwide, and are a significant burden on health care systems. Lysine methyltransferases ...

    • SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling 

      Oudhoff, Menno; Braam, Mitchell JS; Freeman, Spencer A; Wong, Denise; Rattray, David G; Wang, Jia; Antignano, Frann; Snyder, Kimberly; Refaeli, Ido; Hughes, Michael R; McNagny, Kelly M; Gold, Michael R; Arrowsmith, Cheryl H; Sato, Toshiro; Rossi, Fabio MV; Tatlock, John H; Owen, Dafydd R; Brown, Peter J; Zaph, Colby (Journal article; Peer reviewed, 2016)
      Intestinal tumorigenesis is a result of mutations in signaling pathways that control cellular proliferation, differentiation, and survival. Mutations in the Wnt/β-catenin pathway are associated with the majority of intestinal ...