Browsing NTNU Open by Author "Aass, Nina Kathrine"
Now showing items 1-19 of 19
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A comparison of CT based measures of skeletal muscle mass and density from the Th4 and L3 levels in patients with advanced non-small-cell lung cancer
Grønberg, Bjørn Henning; Sjøblom, Bjørg; Wentzel-Larsen, Tore; Baracos, Vickie Elaine; Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Bremnes, Roy M.; Fløtten, Øystein; Bye, Asta; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2018)Background: Muscle mass and density assessed from CT-images at the L3 level are prognostic for survival and predict toxicity in cancer patients. However, L3 is not always included on routine CT-scans. We aimed to investigate ... -
Are emergency admissions in palliative cancer care always necessary? Results from a descriptive study
Hjermstad, Marianne Jensen; Kolflaath, Jan; Løkken, Aud Oddny; Hanssen, Sjur Bjørnar; Normann, Are Peder; Aass, Nina Kathrine (Journal article; Peer reviewed, 2013)Objectives: Patients with advanced cancer are often admitted to hospital as emergency cases. This may not always be medically indicated. Study objectives were to register the reasons for the emergency admissions, to examine ... -
Benefits of Study Participation for Patients with Advanced Cancer Receiving Radiotherapy: A Prospective Observational Study
Bye, Asta; Bjerkeset, Ellen; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Klepstad, Pål; Habberstad, Ragnhild H; Kaasa, Stein; Aass, Nina Kathrine (Peer reviewed; Journal article, 2022)Background: Patients with advanced cancer and bone metastases may have unmet palliative care (PC) needs that go unnoticed during clinical oncological practice. This observational study describes interventions that were ... -
Clinical Predictors for Analgesic Response to Radiotherapy in Patients with Painful Bone Metastases
Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Bjerkeset, Gunnhild; Abramova, Tatiana Mikhailovna; Garcia-Alonso, Elena; Caputo, Mariangela; Rossi, Romina; Boland, Jason W.; Brunelli, Cinzia; Lund, Jo-Åsmund; Kaasa, Stein; Klepstad, Pål (Peer reviewed; Journal article, 2021)Background Radiotherapy (RT) reduces pain in about 60% of patients with painful bone metastases, leaving many patients without clinical benefit. This study assesses predictors for RT effectiveness in patients with painful ... -
Correction to: Norwegian reference values for the Short-Form Health Survey 36: development over time
Jacobsen, Ellisiv Lærum; Bye, Asta; Aass, Nina Kathrine; Fosså, Sophie Dorothea; Grotmol, Kjersti Støen; Kaasa, Stein; Loge, Jon Håvard; Moum, Torbjørn Åge; Hjermstad, Marianne Jensen (Journal article; Peer reviewed, 2017) -
Depression-A Major Contributor to Poor Quality of Life in Patients With Advanced Cancer
Grotmol, Kjersti Støen; Lie, Hanne Cathrine; Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Currow, David; Kaasa, Stein; Moum, Torbjørn Åge; Pigni, Alessandra; Loge, Jon Håvard (Journal article, 2017)Context Quality of life (QoL) and depression are important patient-reported outcomes in cancer care. However, the relative importance of depression severity in predicting QoL remains unclear because of few methodologically ... -
Inflammatory Markers and Radiotherapy Response in Patients With Painful Bone Metastases
Habberstad, Ragnhild H; Aass, Nina Kathrine; Mollnes, Tom Eirik; Damås, Jan Kristian; Brunelli, Cinzia; Rossi, Romina; Garcia-Alonso, Elena; Kaasa, Stein; Klepstad, Pål (Peer reviewed; Journal article, 2022)Context Inflammation is proposed to influence tumor response in radiotherapy (RT). Clinical studies to investigate the relationship between inflammatory markers and RT response is warranted to understand the variable RT ... -
Muscle mass and association to quality of life in non-small cell lung cancer patients
Bye, Asta; Sjøblom, Bjørg; Wentzel-Larsen, Tore; Grønberg, Bjørn Henning; Baracos, Vickie E.; Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Bremnes, Roy M.; Fløtten, Øystein; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2017)Background Cancer wasting is characterized by muscle loss and may contribute to fatigue and poor quality of life (QoL). Our aim was to investigate associations between skeletal muscle index (SMI) and skeletal muscle ... -
Norwegian reference values for the Short-Form Health Survey 36: development over time
Jacobsen, Ellisiv Lærum; Bye, Asta; Aass, Nina Kathrine; Fosså, Sophie Dorothea; Grotmol, Kjersti Støen; Kaasa, Stein; Loge, Jon Håvard; Moum, Torbjørn Åge; Hjermstad, Marianne Jensen (Journal article; Peer reviewed, 2017)Purpose Reference values for patient-reported outcome measures are useful for interpretation of results from clinical trials. The study aims were to collect Norwegian SF-36 reference values and compare with data from 1996 ... -
Overall survival after initial radiotherapy for brain metastases; a population based study of 2140 patients with non-small cell lung cancer
Karlsson, Astrid Telhaug; Hjermstad, Marianne Jensen; Omdahl, Therese; Aass, Nina Kathrine; Skovlund, Eva; Hellebust, Taran Paulsen; Johansen, Safora; Kaasa, Stein; Yri, Olav Erich (Peer reviewed; Journal article, 2021)Background Brain metastases (BM) occur in about 30% of all patients with non-small cell lung cancer (NSCLC). BM treatment guidelines recommend more frequent use of stereotactic radiotherapy (SRT). Overall, studies report ... -
Overall Survival after Radiotherapy for Brain Metastases According to ECOG Status—A Prospective Study of 294 NSCLC Patients
Karlsson, Astrid Telhaug; Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Skovlund, Eva; Kaasa, Stein; Yri, Olav Erich (Journal article; Peer reviewed, 2024)Up to 40% of non-smallcell lung cancer (NSCLC) patients develop brain metastases (BMs). The potential benefits of radiotherapy (RT) in patients with poor performance status (PS) are questionable, with considerable risk for ... -
PALLiative care in ONcology (PALLiON): A cluster-randomised trial investigating the effect of palliative care on the use of anticancer treatment at the end of life
Hjermstad, Marianne Jensen; Pirnat, Aleksandra; Aass, Nina Kathrine; Andersen, Sigve; Astrup, Guro Lindviksmoen; Dajani, Olav; Garresori, Herish; Guldhav, Kristin Vassbotn; Hamre, Hanne Mari; Haukland, Ellinor Christin; Jordal, Frode; Lundeby, Tonje; Løhre, Erik Torbjørn; Mjåland, Svein; Paulsen, Ørnulf; Semb, Karin; Staff, Erik Schistad; Wester, Torunn Elin; Kaasa, Stein (Journal article; Peer reviewed, 2024)Background: Effects on anticancer therapy following the integration of palliative care and oncology are rarely investigated. Thus, its potential effect is unknown. Aim: To investigate the effects of the complex intervention ... -
PALLiON - PALLiative care Integrated in ONcology: Study protocol for a Norwegian national cluster-randomized control trial with a complex intervention of early integration of palliative care
Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Andersen, Sigve; Brunelli, Cinzia; Dajani, Olav; Ahmed, Herish; Hamre, Hanne Mari; Haukland, Ellinor Christin; Holmberg, Mats; Jordal, Frode; Krogstad, Hilde; Lundeby, Tonje; Løhre, Erik T; Mjåland, Svein; Nordbø, Arve; Paulsen, Ørnulf; Staff, Erik Schistad; Wester, Torunn; Kaasa, Stein; Loge, Jon Håvard (Peer reviewed; Journal article, 2020)Background - Several publications have addressed the need for a systematic integration of oncological care focused on the tumor and palliative care (PC) focused on the patient with cancer. The exponential increase in ... -
Patients with advanced cancer and depression report a significantly higher symptom burden than non-depressed patients
Grotmol, Kjersti Støen; Lie, Hanne Cathrine; Loge, Jon Håvard; Aass, Nina Kathrine; Haugen, Dagny Faksvåg; Stone, Patrick C; Kaasa, Stein; Hjermstad, Marianne Jensen (Journal article; Peer reviewed, 2018)Objective Clinical observations indicate that patients with advanced cancer and depression report higher symptom burden than nondepressed patients. This is rarely examined empirically. Study aim was to investigate the ... -
The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial
Jakobsen, Gunnhild; Engstrøm, Morten; Hjermstad, Marianne Jensen; Rosland, Jan Henrik; Aass, Nina Kathrine; Albert, Eva; Kaasa, Stein; Fayers, Peter; Klepstad, Pål; Paulsen, Ørnulf (Peer reviewed; Journal article, 2020)Purpose: Although corticosteroids are frequently used in patients with advanced cancer, few studies have examined the impact of these drugs on patient-reported sleep. We aimed to examine the short-term impact of ... -
Surgery for brain metastases – real-world prognostic factors’ association with survival
Rootwelt, Rebecca; Vik-Mo, Einar Osland; Yri, Olav Erich; Aass, Nina Kathrine; Kaasa, Stein; Skovlund, Eva; Helseth, Eirik; Hjermstad, Marianne Jensen (Journal article, 2021)Background Surgical resection of brain metastases (BM) improves overall survival (OS) in selected patients. Selecting those patients likely to benefit from surgery is challenging. The Graded Prognostic Assessment (GPA) ... -
Surgery for brain metastases—impact of the extent of resection
Winther, Rebecca Rootwelt; Hjermstad, Marianne Jensen; Skovlund, Eva; Aass, Nina Kathrine; Helseth, Eirik; Kaasa, Stein; Yri, Olav Erich; Vik-Mo, Einar O. (Peer reviewed; Journal article, 2022)Background Surgical resection of brain metastases improves symptoms and survival in selected patients. The benefit of gross total resection is disputed, as most patients are believed to succumb from their non-CNS tumor ... -
The Palliative Radiotherapy and Inflammation Study (PRAIS) - Protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain 11 Medical and Health Sciences 1103 Clinical Sciences
Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Abramova, Tatiana Mikhailovna; Baas, Theo; Mørkeset, Siri Tessem; Caraceni, Augusto; Laird, Barry J; Boland, Jason W.; Rossi, Romina; Garcia-Alonso, Elena; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Bjerkeset, Ellen; Bye, Asta; Lund, Jo-Åsmund; Solheim, Tora Skeidsvoll; Vagnildhaug, Ola Magne; Brunelli, Cinzia; Damås, Jan Kristian; Mollnes, Tom Eirik; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2018)Background Radiation therapy (RT) results in pain relief for about 6 of 10 patients with cancer induced bone pain (CIBP) caused by bone metastases. The high number of non-responders, the long median time from RT to pain ... -
The relationship between pro-inflammatory cytokines and pain, appetite and fatigue in patients with advanced cancer
Paulsen, Ørnulf; Laird, Barry J; Aass, Nina Kathrine; Lea, Tor Erling; Fayers, Peter; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2017)Background Systemic inflammation is associated with reduced quality of life and increased symptoms in patients with advanced cancer. The aims of this study were to examine the relationships between inflammatory biomarkers ...