Browsing NTNU Open by Journals "Genes"

Now showing items 1-10 of 10

    • An ‛Aukward’ tale: a genetic approach to discover the whereabouts of the last Great Auks 

      Thomas, Jessica E; Carvalho, Gary R.; Haile, James; Martin, Michael David; Castruita, Jose A. Samaniego; Niemann, Jonas; Sinding, Mikkel Holger Strander; Sandoval-Velasco, Marcela; Rawlence, Nicolas J.; Fuller, Errol; Fjeldså, Jon; Hofreiter, Michael; Stewart, John R; Gilbert, Marcus Thomas Pius; Knapp, Michael (Journal article; Peer reviewed, 2017)
      One hundred and seventy-three years ago, the last two Great Auks, Pinguinus impennis, ever reliably seen were killed. Their internal organs can be found in the collections of the Natural History Museum of Denmark, but the ...

    • APOE Polymorphism and Endocrine Functions in Subjects with Morbid Obesity Undergoing Bariatric Surgery 

      Farup, Per Grønaas; Jansen, Aina; Hestad, Knut; Aaseth, Jan; Rootwelt, Helge (Peer reviewed; Journal article, 2022)
      Background: Obesity is an interplay between genes and the environment, including lifestyle. The genetics of obesity is insufficiently understood. Apolipoprotein E (APOE) genetic polymorphism has been associated with a wide ...

    • APOE Polymorphism Is Associated with Changes in the Kynurenine Pathway 

      Farup, Per Grønaas; Rootwelt, Helge; Hestad, Knut (Peer reviewed; Journal article, 2023)
      Abstract: Background: APOE polymorphism and the Kynurenine pathway (KP) are associated with many disorders, but little is known about associations between APOE polymorphism and the KP. This study explored the associations ...

    • Comparative Mitogenome Analysis of Two Native Apple Snail Species (Ampullariidae, Pomacea) from Peruvian Amazon 

      Mendivil, Alejandro; Ramírez, Rina; Morin Lagos, Jaime Gerardo; Ramirez, Jorge L.; Siccha-Ramirez, Raquel; Britzke, Ricardo; Rivera, Fátima; Ampuero, Andre; Oliveros, Nilda; Congrains, Carlos (Peer reviewed; Journal article, 2023)
      Apple snails of the genus Pomacea Perry, 1810 (Mollusca: Caenogastropoda: Ampullariidae) are native to the Neotropics and exhibit high species diversity, holding cultural and ecological significance as an important protein ...

    • Functional Analyses of Rare Germline Missense BRCA1 Variants Located within and outside Protein Domains with Known Functions 

      Hovland, Henrikke Nilsen; Mchaina, Eunice Kabanyana; Vetti, Hildegunn Høberg; Ariansen, Sarah Louise; Sjursen, Wenche; Van Ghelue, Marijke; Haukanes, Bjørn Ivar; Knappskog, Per Morten; Aukrust, Ingvild; Berge, Elisabet Ognedal (Peer reviewed; Journal article, 2023)
      The BRCA1 protein is implicated in numerous important cellular processes to prevent genomic instability and tumorigenesis, and pathogenic germline variants predispose carriers to hereditary breast and ovarian cancer (HBOC). ...

    • Genetic Rescue of the Highly Inbred Norwegian Lundehund 

      Melis, Claudia; Pertoldi, Cino; Ludington, William Basil; Beuchat, Carol; Qvigstad, Gunnar; Stronen, Astrid Vik (Journal article; Peer reviewed, 2022)
      Augmenting the genetic diversity of small, inbred populations by the introduction of new individuals is often termed “genetic rescue“. An example is the Norwegian Lundehund, a small spitz dog with inbreeding-related health ...

    • Genomic Consequences of Fragmentation in the Endangered Fennoscandian Arctic Fox (Vulpes lagopus) 

      Cockerill, Christopher A.; Hasselgren, Malin; Dussex, Nicolas; Dalén, Love; von Seth, Johanna; Angerbjörn, Anders; Wallén, Johan F.; Landa, Arild; Eide, Nina Elisabeth; Flagstad, Øystein; Ehrich, Dorothee; Sokolov, Aleksandr; Sokolova, Natalya; Norén, Karin (Peer reviewed; Journal article, 2022)
      Accelerating climate change is causing severe habitat fragmentation in the Arctic, threatening the persistence of many cold-adapted species. The Scandinavian arctic fox (V. lagopus) is highly fragmented, with a once ...

    • Low maternal microbiota sharing across gut, breast milk and vagina, as revealed by 16s rRNA gene and reduced metagenomic sequencing 

      Avershina, Ekaterina; Angell, Inga Leena; Simpson, Melanie Rae; Storrø, Ola; Øien, Torbjørn; Johnsen, Roar; Rudi, Knut (Journal article; Peer reviewed, 2018)
      The maternal microbiota plays an important role in infant gut colonization. In this work we have investigated which bacterial species are shared across the breast milk, vaginal and stool microbiotas of 109 women shortly ...

    • PML regulates the epidermal differentiation complex and skin morphogenesis during mouse embryogenesis 

      Polec, Anna; Rowe, Alexander D.; Blicher, Pernille; Suganthan, Rajikala; Bjørås, Magnar; Bøe, Stig Ove (Peer reviewed; Journal article, 2020)
      The promyelocytic leukemia (PML) protein is an essential component of nuclear compartments called PML bodies. This protein participates in several cellular processes, including growth control, senescence, apoptosis, and ...

    • The Relationships between Dopaminergic, Glutamatergic, and Cognitive Functioning in 22q11.2 Deletion Syndrome: A Cross-Sectional, Multimodal 1H-MRS and 18F-Fallypride PET Study 

      van Hooijdonk, Carmen F. M.; Tse, Desmond H. Y.; Roosenschoon, Julia; Ceccarini, Jenny; Booij, Jan; van Amelsvoort, Therese A. M. J.; Vingerhoets, Claudia (Peer reviewed; Journal article, 2022)
      Background: Individuals with 22q11.2 deletion syndrome (22q11DS) are at increased risk of developing psychosis and cognitive impairments, which may be related to dopaminergic and glutamatergic abnormalities. Therefore, in ...