• Diabetes severity and the role of leisure time physical exercise on cardiovascular mortality: the Nord-Trondelag Health study (HUNT), Norway 

      Moe, Børge; Augestad, Liv Berit; Nilsen, Tom Ivar Lund (Journal article; Peer reviewed, 2013)
      Background Physical activity has been associated with lower cardiovascular mortality in people with diabetes, but how diabetes severity influence this association has not been extensively studied. Methods We prospectively ...
    • Genetic deletion of MMP12 ameliorates cardiometabolic disease by improving insulin sensitivity, systemic inflammation, and atherosclerotic features in mice 

      Amor, Melina; Bianco, Valentina; Buerger, Martin; Lechleitner, Margarete; Vujić, Nemanja; Dobrijević, Anja; Akhmetshina, Alena; Pirchheim, Anita; Schwarz, Birgit; Pessentheiner, Ariane R.; Baumgartner, Franziska; Rampitsch, Katharina; Schauer, Silvia; Klobučar, Iva; Degoricija, Vesna; Pregartner, Gudrun; Kummer, Daniel; Svecla, Monika; Sommer, Gerhard; Kolb, Dagmar; Holzapfel, Gerhard; Hoefler, Gerald; Frank, Saša; Norata, Giuseppe Danilo; Kratky, Dagmar (Journal article; Peer reviewed, 2023)
      Background Matrix metalloproteinase 12 (MMP12) is a macrophage-secreted protein that is massively upregulated as a pro-inflammatory factor in metabolic and vascular tissues of mice and humans suffering from cardiometabolic ...
    • Metabolic syndrome and the plasma proteome: from association to causation 

      Elhadad, Mohamed; Wilson, Rory; Zaghlool, Shaza B; Huth, Cornelia; Gieger, Christian; Grallert, Harald; Graumann, Johannes; Rathmann, Wolfgang; Koenig, Wolfgang; Sinner, Moritz F.; Hveem, Kristian; Suhre, Karsten; Thorand, Barbara; Jonasson, Christian; Waldenberger, Melanie; Peters, Annette (Peer reviewed; Journal article, 2021)
      Background The metabolic syndrome (MetS), defined by the simultaneous clustering of cardio-metabolic risk factors, is a significant worldwide public health burden with an estimated 25% prevalence worldwide. The pathogenesis ...