• Estrogen receptor α promotes breast cancer by reprogramming choline metabolism 

      Jia, Min; Andreassen, Trygve; Jensen, Lasse; Bathen, Tone Frost; Sinha, Indranil; Gao, Hui; Zhao, Chunyan; Haldosen, Lars-Arne; Cao, Yihai; Girnita, Leonard; Moestue, Siver Andreas; Dahlman-Wright, Karin (Journal article; Peer reviewed, 2016)
      Estrogen receptor α (ERα) is a key regulator of breast growth and breast cancer development. Here, we report how ERα impacts these processes by reprogramming metabolism in malignant breast cells. We employed an integrated ...
    • MRI Imaging of the Hemodynamic Vasculature of Neuroblastoma Predicts Response to Antiangiogenic Treatment 

      Zormpas-Petridis, Konstantinos; Jerome, Neil Peter; Blackledge, Matthew D.; Carceller, Fernando; Poon, Evon; Clarke, Matthew; McErlean, Ciara; Barone, Guiseppe; Koers, Alexander; Vaidya, Sucheta; Marshall, Lynley; Pearson, Andrew D. J.; Moreno, Lucas; Anderson, John; Sebire, Neil; McHugh, Kieran; Koh, Dow-Mu; Yuan, Yinyin; Chesler, Louis; Robinson, Simon; Jamin, Yann (Journal article; Peer reviewed, 2019)
      Childhood neuroblastoma is a hypervascular tumor of neural origin, for which antiangiogenic drugs are currently being evaluated; however, predictive biomarkers of treatment response, crucial for successful delivery of ...