Browsing NTNU Open by Journals "Basic & Clinical Pharmacology & Toxicology"
Now showing items 1-6 of 6
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Antihistamine use during breastfeeding with focus on breast milk transfer and safety in humans: A systematic literature review
(Journal article; Peer reviewed, 2021)Current data on use of antihistamines during breastfeeding and risks to the breastfed infant are insufficient. The aim of this systematic review was to provide an overview of studies measuring the levels of antihistamines ... -
Direct oral anticoagulant concentrations and adherence in stroke patients
(Journal article; Peer reviewed, 2023)No therapeutic ranges linking drug concentrations of apixaban and rivaroxaban to clinical outcomes have been defined. We investigated whether direct oral anticoagulant (DOAC) concentrations among patients admitted to ... -
Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications
(Peer reviewed; Journal article, 2024)Background A considerable inter-individual variability has been reported in the relationship between methadone doses applied and serum concentrations achieved in methadone maintenance treatment. However, the underlying ... -
Neurotoxic effects of mercury exposure in dental personnel
(Peer reviewed; Journal article, 2019)Numerous studies have reported neurobehavioural effects in dental personnel occupationally exposed to chronic low levels of mercury (Hg). Hg exposure from dental work may also induce various chronic conditions such as ... -
Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project
(Peer reviewed; Journal article, 2023)Data on drug transfer into human breast milk are sparse. This study aimed to quantify concentrations of cetirizine and levocetirizine in breast milk and to estimate drug exposure to infants. Breastfeeding women at least ... -
Transfer of triptans into human breast milk and estimation of infant drug exposure through breastfeeding
(Peer reviewed; Journal article, 2021)Clinical data on the transfer of triptans into human breast milk remain scarce. In a lactation study including 19 breastfeeding women with migraine, we examined the excretion of six different triptans into milk. Following ...